scholarly journals Using the Cigarette Purchase Task to examine the relative reinforcing value of cigarettes among mothers with versus without opioid dependence.

2020 ◽  
Vol 28 (6) ◽  
pp. 706-713 ◽  
Author(s):  
Tyler D. Nighbor ◽  
Sulamunn R. M. Coleman ◽  
Janice Y. Bunn ◽  
Michael J. DeSarno ◽  
Adam L. Morehead ◽  
...  
2020 ◽  
Vol 28 (3) ◽  
pp. 291-298 ◽  
Author(s):  
Alba González-Roz ◽  
Roberto Secades-Villa ◽  
Sara Weidberg ◽  
José Muñiz ◽  
James MacKillop

2020 ◽  
Vol 22 (10) ◽  
pp. 1851-1859 ◽  
Author(s):  
Rachel N Cassidy ◽  
Victoria Long ◽  
Jennifer W Tidey ◽  
Suzanne M Colby

Abstract Introduction Behavioral economic purchase tasks are used to estimate the reinforcing value of drugs by asking participants how much they would purchase across a range of increasing prices. We sought to validate such a task for e-cigarettes in experienced users of advanced generation, tank-style devices. Methods Dual users of cigarettes and e-cigarettes (N = 54) and exclusive e-cigarette users (N = 59) attended one session during which they completed assessments including two versions of the E-cigarette Purchase Task: one that asked how many puffs of their e-cigarette they would purchase in 24 hours at varying prices and one that asked how many mLs of e-liquid they would purchase. We correlated purchase task outcomes with other measures of e-cigarette use. We also compared the tasks across dual and exclusive users. Results Indices derived from the mLs-based task were more likely to be correlated with self-reported use rates, e-cigarette dependence, and cotinine levels than the puffs-based task. Exclusive users showed greater demand on than dual users only on the mLs version when using an F-test comparison method, while multivariate analysis of variance (MANOVA) results showed that dual users showed greater demand only on the puffs task. Conclusions Results indicate that the mLs version had greater validity than the puffs version in terms of clinical indices. Dual users may still be on a trajectory to fully switching to e-cigarettes; thus, puffs as a measure may be more intuitive, as this measure is shared by cigarettes and e-cigarettes. For exclusive users, the unit they purchase their e-liquid in may be the most relevant unit and better capture their demand for that product. Implications Behavioral economic purchase tasks have been widely used to understand nicotine use. We have developed two versions of a purchase task for e-cigarette use and compared the two versions in users of advanced generation e-cigarette devices. We found that the mLs version of the task better-reflected use patterns relative to a puffs version, which suggests that participants struggle to place monetary value on a unit of consumption (ie, puffs). Validated measures of e-cigarette reinforcement will be important as researchers and regulators determine which features of these products contribute to reinforcing efficacy.


2013 ◽  
Author(s):  
Sean M. Murphy ◽  
Paul A. Fishman ◽  
Sterling M. McPherson ◽  
Dennis G. Dyck ◽  
John M. Roll

2007 ◽  
Author(s):  
Ryan K. Lanier ◽  
Joseph A. Harrison ◽  
Elie S. Nuwayser ◽  
Annie Umbricht ◽  
George E. Bigelow

2014 ◽  
Vol 21 (1) ◽  
pp. 86-90
Author(s):  
Robertas Badaras ◽  
Gabija Dragelytė ◽  
Indrė Vaitekonytė ◽  
Juozas Ivaškevičius ◽  
Jūratė Šipylaitė

Materials and Methods. Published articles on the opioid abuse and methods of opioid detoxification were identified by searching medical databases, using corresponding literature and were also searched manually for applicable papers. The search was limited to articles published from 1985 through 2014. Results. Opioid dependence determine pathophysiologic changes in the dopaminergic pathways of the organism, as well as the alterations in the stress-responsive hypothalamic-pituitary-adrenal axis. The usage of opioid antagonists in the early stages of withdrawal, can lead the effectiveness of opioid detoxification to 100%. Rapid opioid detoxification do not remove all the symptoms of abstinence. Negative aspects, concerning the procedure, while using prevention, can be reduced to the minimum risk. Rapid opioid detoxification, comparing it with Ultrarapid opioid detoxification procedure, diverges as less financial resources and a lower risk containing technique. Conclusions. Use of antagonists may reduce the duration of withdrawal, thus reducing the overall severity of withdrawal and increasing the chances of successful completion. This technique facilitates commencement of naltrexone treatment. Dosing regimens used in clinical trials vary. Subsequent results do not correlate with the methods of detoxification.


2002 ◽  
Author(s):  
Shuyuan Yu ◽  
Li Ying
Keyword(s):  

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