Examining cognitive speed and accuracy dysfunction in youth and young adults with pediatric-onset multiple sclerosis using a computerized neurocognitive battery.

2021 ◽  
Vol 35 (4) ◽  
pp. 388-398
Author(s):  
Emily Barlow-Krelina ◽  
Tracy L. Fabri ◽  
Julia O'Mahony ◽  
Ruben C. Gur ◽  
Raquel E. Gur ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Young Adults ◽  
Youth And Young Adults ◽  
Cognitive Speed ◽  
Speed And Accuracy ◽  
Pediatric Onset

scholarly journals 7T MRI Visualization of Cortical Lesions in Adolescents and Young Adults with Pediatric-Onset Multiple Sclerosis

2017 ◽  
Vol 27 (5) ◽  
pp. 447-452 ◽  
Author(s):  
Ritobrato Datta ◽  
Varun Sethi ◽  
Sophia Ly ◽  
Amy T. Waldman ◽  
Sona Narula ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Young Adults ◽  
Adolescents And Young Adults ◽  
Cortical Lesions ◽  
Pediatric Onset

scholarly journals No Evidence for Impairment of Venous Hemodynamics in Children or Young Adults with Pediatric-Onset Multiple Sclerosis

2013 ◽  
Vol 34 (12) ◽  
pp. 2366-2372 ◽  
Author(s):  
S. Laughlin ◽  
C.K. Macgowan ◽  
J. Traubici ◽  
K. Chan ◽  
S. Khan ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Young Adults ◽  
Pediatric Onset

scholarly journals Quality of Life, Cognition and Mood in Adults with Pediatric Multiple Sclerosis

2016 ◽  
Vol 43 (3) ◽  
pp. 368-374 ◽  
Author(s):  
Kristen M. Krysko ◽  
Paul O’Connor
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Young Adults ◽  
Cognitive Function ◽  
Physical Disability ◽  
Normative Data ◽  
Short Form ◽  
Physical Hrqol ◽  
Pediatric Onset

AbstractBackground: Pediatric onset multiple sclerosis (MS) negatively affects cognitive function, mood and health related quality of life (HRQOL). We aimed to explore the cognitive, psychological and HRQOL impacts of pediatric MS on young adults and to explore the relationships between disability, disease duration, cognition, mood and HRQOL in this hypotheses generating study. Methods: Thirty-four young adults with pediatric onset MS at St. Michael’s Hospital in Toronto were included in this cross-sectional study (mean age 21.3 years, 56% female). Participants completed assessments of physical disability (Expanded Disability Status Scale (EDSS)), cognitive function (Symbol Digit Modalities Test (SDMT)), mood (Beck Depression Inventory II (BDI-II)), and HRQOL (Short Form Health Survey (SF-36v2)). Findings were compared to age- and gender- matched normative data. Results: Individuals with pediatric MS performed worse on the SDMT compared to normative data, with 53% demonstrating cognitive impairment. There was no difference in BDI-II scores from normative data, but 21% showed at least mild depression. There was a non-significant impairment in physical HRQOL compared to normative data. Decreased physical HRQOL was related to disability (EDSS), while mental HRQOL was related to depression (BDI-II). Conclusions: Young adults with pediatric MS have reduced cognitive function. Non-significant reductions in HRQOL may be partly attributed to physical disability and depression. These factors should be addressed in the care of adults with pediatric MS. Further studies including control groups and longitudinal design are needed to confirm these findings.

805-P: Barriers and Facilitators of Participation in Clinical Trials among Youth and Young Adults with Type 1 Diabetes and Their Caregivers

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 805-P
Author(s):  
SARAH C. WESTEN ◽  
LINDSAY M. ANDERSON ◽  
SAMANTHA A. BARRY ◽  
SYDNEY LOOK ◽  
STEFANIA PINTO ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Type 1 Diabetes ◽  
Young Adults ◽  
Barriers And Facilitators ◽  
Youth And Young Adults
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