Review of Families, illness, and disability: An integrative treatment model.

1995 ◽  
Vol 13 (3-4) ◽  
pp. 405-407
Author(s):  
Jeri Hepworth
Keyword(s):  
Treatment Model ◽  
Integrative Treatment ◽  
Integrative Treatment Model

Need-Adapted Treatment of Schizophrenia: Family Interventions

1994 ◽  
Vol 164 (S23) ◽  
pp. 89-96 ◽  
Author(s):  
Klaus Lehtinen
Keyword(s):  
Social Functioning ◽  
Therapeutic Process ◽  
Treatment Model ◽  
Integrative Treatment ◽  
Family Interventions ◽  
Starting Point ◽  
The Family ◽  
Integrative Treatment Model ◽  
Network Therapy

Need-adapted treatment of schizophrenia is an integrative treatment model developed in the Turku Schizophrenia Project. It is based on the interactional viewpoint and understanding on the interactional level. Experience of family and network therapy has shown that immediate interactions-oriented intervention is an essential starting-point for the treatment. It creates the possibility for the treatment as a whole to become a therapeutic process. For clinical purposes, it has seemed logical to divide the patients into three groups; the methods and focus of the family-oriented work differ somewhat between the groups. The main separator between these is the level of social functioning before the psychosis.

Molecular biomarkers to track clinical improvement following an integrative treatment model in autistic toddlers

2021 ◽  
pp. 1-18
Author(s):  
Ignazio S. Piras ◽  
Filippo Manti ◽  
Anna Costa ◽  
Valentina Carone ◽  
Bruna Scalese ◽  
...  
Keyword(s):  
Gene Expression ◽  
Therapeutic Intervention ◽  
Speech Therapy ◽  
Autism Spectrum ◽  
Treatment Model ◽  
Cognitive Behavioral Intervention ◽  
Clinical Scales ◽  
Integrative Treatment Model ◽  
One Year ◽  
Disease Specific

Abstract Objective: Identifying an objective, laboratory-based diagnostic tool (e.g., changes in gene expression), when used in conjunction with disease-specific clinical assessment, could increase the accuracy of the effectiveness of a therapeutic intervention. Methods: We assessed the association between treatment outcome and blood RNA expression before the therapeutic intervention to post-treatment (after one year) of five Autism Spectrum Disorder (ASD) toddlers who underwent an intensive cognitive-behavioral intervention integrated with psychomotor and speech therapy. Results: We found 113 significant Differentially Expressed genes (DEGs) enriched for the nervous system, immune system, and transcription and translation-related pathways. Some of these genes, as MALAT-1, TSPO, and CFL1, appear to be promising candidates. Conclusion: Our findings show that changes in peripheral gene expression could be used in conjunction with clinical scales to monitor a rehabilitation intervention’s effectiveness in toddlers affected by ASD. These results need to be validated in a larger cohort.

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