Interhemispheric transfer of extinction of the active avoidance reaction in rats.

1975 ◽  
Vol 89 (5) ◽  
pp. 427-432
Author(s):  
S. Islam ◽  
J. Bures ◽  
O. Buresova
2013 ◽  
Vol 11 (2) ◽  
pp. 26-30
Author(s):  
Denis Vladimirovich Sosin ◽  
Andrey Viktorovich Yevseyev ◽  
Vitaliy Andreyevich Pravdivtsev ◽  
Marina Anatolyevna Yevseyeva ◽  
Petr Dmitriyevich Shabanov

The dynamic of active avoidance reaction in consist of a defense conditioned reflex after intragastric administration of new selenium-containing metal-complex substances πQ1983 (100 mg/kg) possessing protective action during development of acute exogenous hypoxia in animal have been studied in experiments on mice. Timing data of the active avoidance reaction in experiments on formerly trained mice under action of this substance used in same doze were analyzed. It was established that substance πQ1983 blocks formation of conditioned reflex. In the group of trained mice antihypoxant πQ1983 increases a latent period of the avoidance reaction and decreases the avoidance time. All found effects provided by intragastric administration of the antihypoxant were short-term (15– 20 h) and reversible. The results were compared with effects of antihypoxant amthizole.


1992 ◽  
Vol 48 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Eugeniusz Nikolaev ◽  
Tomasz Werka ◽  
Leszek Kaczmarek

2015 ◽  
Vol 45 (2) ◽  
pp. 173-178 ◽  
Author(s):  
A. N. Inozemtsev ◽  
A. E. Agapitova ◽  
S. B. Bokieva ◽  
N. Yu. Glazova ◽  
N. G. Levitskaya ◽  
...  

2000 ◽  
Vol 59 (3) ◽  
pp. 150-158 ◽  
Author(s):  
Nadia Ortiz ◽  
Michael Reicherts ◽  
Alan J. Pegna ◽  
Encarni Garran ◽  
Michel Chofflon ◽  
...  

Patients suffering from Multiple Sclerosis (MS) have frequently been found to suffer from damage to callosal fibers. Investigations have shown that this damage is associated with signs of hemisphere disconnections. The aim of our study was to provide evidence for the first signs of interhemispheric dysfunction in a mildly disabled MS population. Therefore, we explored whether the Interhemispheric Transfer (IT) deficit is multi-modal and sought to differentiate two MS evolution forms, on the basis of an interhemispheric disconnection index. Twenty-two patients with relapsing-remitting form of MS (RRMS) and 14 chronic-progressive (CPMS) were compared with matched controls on four tasks: a tachistoscopic verbal and non-verbal decision task, a dichotic listening test, cross tactile finger localization and motor tapping. No overall impairment was seen. The dichotic listening and lexical decision tasks were the most sensitive to MS. In addition, CPMS patients' IT was more impaired and was related to the severity of neurological impairment. The different sizes of the callosal fibers, which determine their vulnerability, may explain the heterogeneity of transfer through the Corpus Callosum. Therefore, evaluation of IT may be of value as an index of evolution in MS.


Sign in / Sign up

Export Citation Format

Share Document