Green Tea Extract on Body Weight and Activity of Naive Long-Evans Rats

2011 ◽  
Author(s):  
Jenna M. Bell ◽  
Joanne R. Knox ◽  
Venita S. Oliver
Oncotarget ◽  
2017 ◽  
Vol 8 (58) ◽  
pp. 99093-99103 ◽  
Author(s):  
Nagi B. Kumar ◽  
Roshni Patel ◽  
Julio Pow-Sang ◽  
Philippe E. Spiess ◽  
Raoul Salup ◽  
...  

2013 ◽  
Vol 386 (8) ◽  
pp. 733-745 ◽  
Author(s):  
Jae-Hyung Park ◽  
Yoon Jung Choi ◽  
Yong Woon Kim ◽  
Sang Pyo Kim ◽  
Ho-Chan Cho ◽  
...  

2012 ◽  
Vol 9 (1) ◽  
pp. 41
Author(s):  
Alpha Olivia Hidayati ◽  
Wiryatun Lestariana ◽  
Emy Huriyati

Background: Overweight and obesity were risk factors of various degenerative diseases. Green tea extract contains polyphenol compounds, particularly catechins which act as antioxidants, fat dissolvent and aid lipolysis. Thus, it is necessary to study the use of green tea as an alternative treatment to overcome overweight.Objective: To identify the effect of green tea extract supplementation on body weight and malondialdehide (MDA) level of overweight women in Yogyakarta District Health Office.Method: This was an experimental study with double-blind randomized controlled trial design. Subject of the study were divided into two groups; one group consumed green tea extract capsules and the other consumed placebo. Weight, 6 times 24 hours recall, and level of MDA were measured on every subject.Results: The results revealed that green tea extract has a weight-reducing effect and decrease MDA level of overweight women, though the reduction of weight and MDA level was not significant (p>0,05). Weight loss of 1.3% was observed in the treatment group, whereas the control group has an increase of 0.6% body weight, but the weight change was not significant (p=0.501, p=0.620). Changes in body weight after 12 weeks of treatment showed a significant disparity between the two groups (p=0.000). MDA level decreased by 10% in the treatment group compared to 8.3% in the control group. MDA levels pre and post intervention was significantly different in the treatment group (p=0.006), whereas in the control group there was no significant discrepancy observed (p=0.123). However, changes in MDA levels after 12 weeks of treatment showed no significant differences among groups (p=0.278). The mean nutrient intakes of subjects were still below the recommended dietary allowance (RDA), except for protein.Conclusion: Green tea extract had a weight-reducing effect and decrease MDA level of overweight women in Yogyakarta District Health Office, though the reduction was not statistically significant.


2019 ◽  
pp. 1-5
Author(s):  
Nahla S. El-Shenawy ◽  
Reham Z. Hamza ◽  
Fawziah A. Al-Salmi

Monosodium glutamate (MSG) is used worldwide as a food additive, the survey has disclosed some of MSG's deleterious effects on various organs and tissues of rats. This research was achieved to determine the impact of MSG on the albino rats' antioxidant and histology of cardiac tissue. 48 male rats were divided into six groups of eight rats each. Group one used for monitoring and normal saline, whereas rats of group two were given the lower dosage of MSG 6 mg/Kg, rats in group three received 17.5 m/kg body weight of MSG, while rats in group four were given 10 mg/kg body weight of zinc oxide nanoparticles /green tea extract (ZnO NPs/GTE) complex, the fifth and sixth groups were treated with the lower and the higher doses of MSG with ZnO NP/GTE complex for 30 days. Each animal was sacrificed at the end of the treatment period and the heart was thoroughly separated, determining the antioxidant parameter and the histopathological changes. MSG administration to the rats has shown a substantial rise in peroxidation of cardiac heart tissue, decline in the activities of catalase, superoxide dismutase, and glutathione peroxidase beside the decrease in the glutathione level as compared to those in the control animals. The treatment the induced-rats with MSG using complex showed some degree of recovery by a reduction in LPO of the heart and enhancement of antioxidant enzymes. The findings suggested that the intrinsic antioxidant of the heart tissue can significantly be alternated with the use of MSG in a dose-dependent manner and these changes could be improved by using the green ZnO NPs complex. This complex acts as a factor to decrease the histological damage that could be happening by the induction of MSG.


2011 ◽  
Vol 23 (3) ◽  
Author(s):  
Dhona Afriza

This research aimed to identify the effect of inhaling mercury on the hepar cells of white mice and the role of green tea extract as an antioxidant on such hepar cells having exposed to mercury histopathologically. It was an experimental research by using 48 male white mice (Mus musculus) as the sample. The sample was divided into 8 groups i.e.: A, B, C, and D, which were given treatment for 3 and 6 weeks. Each group consisted of 6 mice. A group was a negative control which did not get any treatment. Group B as a positive control group was exposed to mercury. Group C was exposed to mercury and was given green tea extract at dosage 0.52 mg/20 gr of body weight. Group D was exposed by mercury and was given green tea extract at dosage 1.04 mg/ 20 gr of body weight. All white mice in the group B, C, and D were exposed to mercury through inhalation for 4 hours daily. To identified the effect of mercury, the hepar cells in all 4 groups were examined at the 3rd and 6th week by making histopathologic preparation in the Histopathology Laboratory Faculty of Medicine Universitas Andalas. Then, the preparation was examined through Binocular Light Microscope in ordered to see the deficient occurred. The data obtained were analyzed by ANOVA method and independent T-test with confidence level = 95%. It was revealed that the hepar cells that were being exposed to mercury regularly were being degenerates. Then, the amount of green tea extract given reduces the degeneration occurred.


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