Attack behavior in mice: Implication of the steroid sulfatase gene mapped on the pairing region of the X-Y-chromosomes

2000 ◽  
Author(s):  
P. L. Roubertoux ◽  
S. Mortaud ◽  
L. Nicolas ◽  
I. Le Roy ◽  
S. Tordjma
Nature ◽  
1984 ◽  
Vol 311 (5983) ◽  
pp. 259-261 ◽  
Author(s):  
H. J. Cooke ◽  
W. A. R. Brown ◽  
G. A. Rappold
Keyword(s):  

Genetics ◽  
1987 ◽  
Vol 116 (3) ◽  
pp. 465-468
Author(s):  
Elisabeth A Keitges ◽  
Daniel F Schorderet ◽  
Stanley M Gartler

ABSTRACT Dosage studies and the inheritance pattern of the gene for steroid sulfatase (Sts) in the mouse have previously provided indirect evidence for a functional Y-linked allele which recombines obligatorily with its X-linked allele in male meiosis. In this study, we have investigated the linkage relationship of Sts and the sex-reversed mutation (Sxr), a gene which is known to reside in the pairing region of the Y chromosome. The results clearly demonstrate that Sxr and Sts are linked in a region of obligatory recombination and Sts maps proximal to Sxr with most recombinants occurring proximal to the two genes.


2017 ◽  
Vol 152 (3) ◽  
pp. 137-147 ◽  
Author(s):  
Roberta B. Sciurano ◽  
Geraldine De Luca ◽  
I. Mónica Rahn ◽  
Alberto J. Solari

The heteromorphic X and Y chromosomes behave in a special way in mammalian spermatocytes; they form the XY body and synapse only partially. The aim of this article was to study the origin and the role of the special differentiations in the XY pair of the domestic cat during pachytene by analyzing its fine structural characteristics and the immunolocalization of the main meiotic proteins SYCP3, SYCP1, SYCE3, SMC3, γ-H2AX, BRCA1, H3K27me3, and MLH1. The cat XY body shows particularly striking structures: an extreme degree of axial fibrillation in late pachynema and a special location of SYCP3-containing fibrils, bridging different regions of the main X axis, as well as one bridge at the inner end of the pairing region that colocalizes with the single mandatory MLH1 focus. There are sequential changes, first bullous expansions, then subdivision into fibrils, all involving axial thickening. The chromatin of the XY body presents the usual features of meiotic sex chromosome inactivation. An analysis of the XY body of many eutherians and metatherians suggests that axial thickenings are primitive features. The sequential changes in the mass and location of SYCP3-containing fibers vary among the clades because of specific processes of axial assembly/disassembly occurring in different species.


2019 ◽  
Vol 13 (4) ◽  
pp. 325-333
Author(s):  
Xu Liu ◽  
Xiaoqiang Di ◽  
Jinqing Li ◽  
Huamin Yang ◽  
Ligang Cong ◽  
...  

Background: User behavior models have been widely used to simulate attack behaviors in the security domain. We revised all patents related to response to attack behavior models. How to decide the protected target against multiple models of attack behaviors is studied. Methods: We utilize one perfect rational and three bounded rational behavior models to simulate attack behaviors in cloud computing, and then investigate cloud provider’s response based on Stackelberg game. The cloud provider plays the role of defender and it is assumed to be intelligent enough to predict the attack behavior model. Based on the prediction accuracy, two schemes are built in two situations. Results: If the defender can predict the attack behavior model accurately, a single-objective game model is built to find the optimal protection strategy; otherwise, a multi-objective game model is built to find the optimal protection strategy. Conclusion: The numerical results prove that the game theoretic model performs better in the corresponding situation.


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