Cutting-Edge Basic Research Awards (PAR-03-017)

2003 ◽  
Author(s):  
Keyword(s):  
10.29007/tgc4 ◽  
2019 ◽  
Author(s):  
Fred Freitas

DL reasoners were developed with cutting-edge performance, implementing plenty of specific optimization techniques over tableaux-based methods, which took over the field. However, promising methods may have been neglected in such a scenario, in which the tough competition is often focused on gains through optimizations. Therefore, perhaps there is still room available for “basic research” on DL reasoning. The purpose of this work is to stimulate research on trying out DL calculi other than tableaux. Such endeavors should be carried out by making a careful, detailed comparison between tableaux and other inference methods in a systematic way: first starting with simpler languages (like ALC) without any optimizations. Then gradually including optimizations and comparing them; and continuing these interactive steps: enhancing language expressivity, including optimizations, and testing until reaching the most expressive DL fragments such as SROIQ. The comparison can also be done by in terms memory usage and algorithm asymptotic analysis, with worst and average cases, etc. The rationale is identifying whether there are fragments which are more suitable to certain inference methods, as well as which aspects or constructs (e.g., the costliest combinations, which usually involve inverses, nominals, equalities, etc) are sensitive to which calculus.


Homeopathy ◽  
2017 ◽  
Vol 107 (01) ◽  
pp. 050-054
Author(s):  
Angelina Mosley ◽  
E. Roberts ◽  
Hazel Partington ◽  
Katharina Gaertner ◽  
Peter Fisher ◽  
...  

AbstractThe third international conference on “Cutting Edge Research in Homeopathy” organised by the Homeopathy Research Institute (HRI) was held on the inspiring and historic island of Malta from 9th to 11th of June, 2017. One hundred and two abstracts underwent peer review by the HRI Scientific Advisory Committee and external experts to produce the programme of 36 oral presentations and 37 posters, presented by researchers from 19 countries. The 2.5-day programme covered a diverse range of topics, including quantitative and qualitative clinical research, basic research, veterinary research, and provings. These intensive plenary and parallel sessions were interspersed with multiple opportunities for delegates to discuss and exchange ideas, in particular through interactive panel discussions and a pre-conference workshop. The continuing commitment of the homeopathy research community to generate high-quality studies in this rapidly evolving field was clear. In this conference report, we present highlights from this memorable event.


Author(s):  
Jong Min An ◽  
Youngwon Ju ◽  
Jeong Hee Kim ◽  
Hyein Lee ◽  
Yuna Jung ◽  
...  

Nanozymes are nanostructure-based materials which mimic the enzymatic characteristics of natural enzyme. Biological applications of nanozymes have been highlighted in basic research, industry, and translational medicine as a new cutting-edge...


Author(s):  
Hardip Kaur Dhillon ◽  
Beatrice Low Wei Jin

Evidence-based medicine (EBM) is now considered a fundamental basis for clinical practices globally. There is an enormous necessity of going beyond merely reading research articles to actually applying research studies to solve patient management problems on a day to day basis. In order to have a cutting edge in a very competitive, international trade of education, Monash University Malaysia encourages Year 1 and 2 undergraduates to engage in various research projects, available within the School of Medicine during their semester breaks. This paper demonstrates a student’s use of experiential learning, reflective journaling and blended Learning while engaging in a research project. The basic research skills acquired early in the undergraduate MBBS curriculum is expected to achieve advance level research skills as the medical student completes the fifth year of the course. Hence, today’s cutting edge of developing research skills early increases the chances of tomorrow’s employability and employment in evidence based health care settings.


Author(s):  
J. Temple Black

The output of the ultramicrotomy process with its high strain levels is dependent upon the input, ie., the nature of the material being machined. Apart from the geometrical constraints offered by the rake and clearance faces of the tool, each material is free to deform in whatever manner necessary to satisfy its material structure and interatomic constraints. Noncrystalline materials appear to survive the process undamaged when observed in the TEM. As has been demonstrated however microtomed plastics do in fact suffer damage to the top and bottom surfaces of the section regardless of the sharpness of the cutting edge or the tool material. The energy required to seperate the section from the block is not easily propogated through the section because the material is amorphous in nature and has no preferred crystalline planes upon which defects can move large distances to relieve the applied stress. Thus, the cutting stresses are supported elastically in the internal or bulk and plastically in the surfaces. The elastic strain can be recovered while the plastic strain is not reversible and will remain in the section after cutting is complete.


Author(s):  
M. Nishigaki ◽  
S. Katagiri ◽  
H. Kimura ◽  
B. Tadano

The high voltage electron microscope has many advantageous features in comparison with the ordinary electron microscope. They are a higher penetrating efficiency of the electron, low chromatic aberration, high accuracy of the selected area diffraction and so on. Thus, the high voltage electron microscope becomes an indispensable instrument for the metallurgical, polymer and biological specimen studies. The application of the instrument involves today not only basic research but routine survey in the various fields. Particularly for the latter purpose, the performance, maintenance and reliability of the microscope should be same as those of commercial ones. The authors completed a 500 kV electron microscope in 1964 and a 1,000 kV one in 1966 taking these points into consideration. The construction of our 1,000 kV electron microscope is described below.


Author(s):  
M.J. Hennessy ◽  
E. Kwok

Much progress in nuclear magnetic resonance microscope has been made in the last few years as a result of improved instrumentation and techniques being made available through basic research in magnetic resonance imaging (MRI) technologies for medicine. Nuclear magnetic resonance (NMR) was first observed in the hydrogen nucleus in water by Bloch, Purcell and Pound over 40 years ago. Today, in medicine, virtually all commercial MRI scans are made of water bound in tissue. This is also true for NMR microscopy, which has focussed mainly on biological applications. The reason water is the favored molecule for NMR is because water is,the most abundant molecule in biology. It is also the most NMR sensitive having the largest nuclear magnetic moment and having reasonable room temperature relaxation times (from 10 ms to 3 sec). The contrast seen in magnetic resonance images is due mostly to distribution of water relaxation times in sample which are extremely sensitive to the local environment.


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