Discrimination of temporal regularity in rats (Rattus norvegicus) and humans (Homo sapiens).

2020 ◽  
Vol 134 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Alexandre Celma-Miralles ◽  
Juan M. Toro
Keyword(s):  
Rattus Norvegicus ◽  
Homo Sapiens ◽  
Temporal Regularity

scholarly journals The easy-to-hard effect in human (Homo sapiens) and rat (Rattus norvegicus) auditory identification.

2008 ◽  
Vol 122 (2) ◽  
pp. 132-145 ◽  
Author(s):  
Estella H. Liu ◽  
Eduardo Mercado ◽  
Barbara A. Church ◽  
Itzel Orduña
Keyword(s):  
Rattus Norvegicus ◽  
Homo Sapiens

scholarly journals Thermophilic, Reversible γ-Resorcylate Decarboxylase from Rhizobium sp. Strain MTP-10005: Purification, Molecular Characterization, and Expression

2004 ◽  
Vol 186 (20) ◽  
pp. 6855-6863 ◽  
Author(s):  
Masahiro Yoshida ◽  
Nobuhiro Fukuhara ◽  
Tadao Oikawa
Keyword(s):  
Rattus Norvegicus ◽  
Homo Sapiens ◽  
Polyacrylamide Gel Electrophoresis ◽  
Sodium Dodecyl ◽  
Gel Filtration ◽  
Hypothetical Protein ◽  
Cell Extract ◽  
Amino Acid Residues ◽  
Sequence Identities ◽  
Rhizobium Sp

ABSTRACT We found the occurrence of thermophilic reversible γ-resorcylate decarboxylase (γ-RDC) in the cell extract of a bacterium isolated from natural water, Rhizobium sp. strain MTP-10005, and purified the enzyme to homogeneity. The molecular mass of the enzyme was determined to be about 151 kDa by gel filtration, and that of the subunit was 37.5 kDa by sodium dodecyl sulfate-polyacrylamide gel electrophoresis; in other words, the enzyme was a homotetramer. The enzyme was induced specifically by the addition of γ-resorcylate to the medium. The enzyme required no coenzyme and did not act on 2,4-dihydroxybenzoate, 2,5-dihydroxybenzoate, 3,4-dihydroxybenzoate, 3,5-dihydroxybenzoate, 2-hydroxybenzoate, or 3-hydroxybenzoate. It was relatively thermostable to heat treatment, and its half-life at 50°C was estimated to be 122 min; furthermore, it catalyzed the reverse carboxylation of resorcinol. The values of k cat/Km (mΜ−1 · s−1) for γ-resorcylate and resorcinol at 30°C and pH 7 were 13.4 and 0.098, respectively. The enzyme contains 327 amino acid residues, and sequence identities were found with those of hypothetical protein AGR C 4595p from Agrobacterium tumefaciens strain C58 (96% identity), 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (32%), and 2-amino-3-carboxymuconate-6-semialdehyde decarboxylases from Bacillus cereus ATCC 10987 (26%), Rattus norvegicus (26%), and Homo sapiens (25%). The genes (graA [1,230 bp], graB [888 bp], and graC [1,056 bp]) that are homologous to those in the resorcinol pathway also exist upstream and downstream of the γ-RDC gene. Judging from these results, the resorcinol pathway also exists in Rhizobium sp. strain MTP-10005, and γ-RDC probably catalyzes a reaction just before the hydroxylase in it does.

scholarly journals Navigating with fingers and feet: Analysis of human (Homo sapiens) and rat (Rattus norvegicus) movement organization during nonvisual spatial tasks.

2010 ◽  
Vol 124 (4) ◽  
pp. 381-394 ◽  
Author(s):  
Douglas G. Wallace ◽  
Jenny R. Köppen ◽  
Jeana L. Jones ◽  
Shawn S. Winter ◽  
Steve J. Wagner
Keyword(s):  
Rattus Norvegicus ◽  
Homo Sapiens ◽  
Movement Organization ◽  
Spatial Tasks

scholarly journals SmProt: a reliable repository with comprehensive annotation of small proteins identified from ribosome profiling

2021 ◽  
Author(s):  
Yanyan Li ◽  
Honghong Zhou ◽  
Xiaomin Chen ◽  
Yu Zheng ◽  
Quan Kang ◽  
...  
Keyword(s):  
Genetic Variants ◽  
Rattus Norvegicus ◽  
Homo Sapiens ◽  
Ribosome Profiling ◽  
Open Reading Frames ◽  
Small Proteins ◽  
Data Volume ◽  
Reading Frames ◽  
Disease Specific ◽  
Small Open Reading Frames

Small proteins specifically refer to proteins consisting of less than 100 amino acids translated from small open reading frames (sORFs), which were usually missed in previous genome annotation. The significance of small proteins has been revealed in current years, along with the discovery of their diverse functions. However, systematic annotation of small proteins is still insufficient. SmProt was specially developed to provide valuable information on small proteins for scientific community. Here we present the update of SmProt, which emphasizes reliability of translated sORFs, genetic variants in translated sORFs, disease-specific sORFs translation events or sequences, and significantly increased data volume. More components such as non-AUG translation initiation, function, and new sources are also included. SmProt incorporated 638,958 unique small proteins curated from 3,165,229 primary records, which were computationally predicted from 419 ribosome profiling (Ribo-seq) datasets and collected from the literature and other sources originating from 370 cell lines or tissues in 8 species (Homo sapiens, Mus musculus, Rattus norvegicus, Drosophila melanogaster, Danio rerio, Saccharomyces cerevisiae, Caenorhabditis elegans, and Escherichia coli). In addition, small protein families identified from human microbiomes were collected. All datasets in SmProt are free to access, and available for browse, search, and bulk downloads at http://bigdata.ibp.ac.cn/SmProt/.

scholarly journals A catalog of CasX genome editing sites in common model organisms

2019 ◽  
Author(s):  
Elisha D.O. Roberson
Keyword(s):  
Genome Editing ◽  
Danio Rerio ◽  
Rattus Norvegicus ◽  
Reference Strain ◽  
Homo Sapiens ◽  
Model Organisms ◽  
Dna Endonuclease ◽  
Unique Site ◽  
Reference Genomes ◽  
Per Gene

AbstractDpbCasX, also called Cas12e, is an RNA-guided DNA endonuclease isolated from Deltaproteobacteria. In this paper I characterized the CasX-compatible genome editing sites in the reference genomes of yeast (Saccharomyces cerevisiae), flatworms (Caenorhabditis elegans), flies (Drosophila melanogaster), zebrafish (Danio rerio), mouse (Mus musculus), rats (Rattus norvegicus), and humans (Homo sapiens). Across those genomes there were >27,000 CasX sites per megabase on average. More than 90% of genes in each genome had at least one unique site overlapping an exon, with median unique sites per gene of 6 – 45. I also annotated sites in the GRCm38 reference and 15 additional mouse strain genomes. The presence of specific guide sequences varied amongst the strains, with CAST/EiJ and PWK/PhJ showing the greatest divergence from the reference strain. The high density of CasX sites and number of exon overlapping sites suggests that CasX has the potential to be used as a common genome editor.

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