Affective instability, family history of mood disorders, and neurodevelopmental disturbance.

2011 ◽  
Vol 2 (3) ◽  
pp. 220-229 ◽  
Author(s):  
Howard Berenbaum ◽  
Keith Bredemeier ◽  
M. Tyler Boden ◽  
Renee J. Thompson ◽  
Melissa Milanak
Keyword(s):  
Family History ◽  
Mood Disorders ◽  
Affective Instability ◽  
History Of

Obtaining a Family Psychiatric History: Is it Worth the Effort?

1993 ◽  
Vol 38 (9) ◽  
pp. 590-594 ◽  
Author(s):  
Ronald A. Remick ◽  
Adele D. Sadovnick ◽  
Boris Gimbarzevsky ◽  
Raymond W. Lam ◽  
Athanasios P. Zis ◽  
...  
Keyword(s):  
Family History ◽  
Psychiatric Disorder ◽  
Mood Disorder ◽  
Mood Disorders ◽  
Medical Records ◽  
Psychiatric History ◽  
First Degree Relatives ◽  
History Of ◽  
Generated Family ◽  
Index Cases

The purpose of this study was to determine whether, for first-degree relatives of patients presenting to a mood disorders clinic, family history information on psychiatric conditions collected by a psychiatrist and incorporated into the patient's medical records is as informative as that gathered during an interview specifically designed to collect family history data. The study group consisted of 472 first-degree relatives of 78 randomly selected index cases from a large mood disorders genetic database. Family history of psychiatric disorders recorded in regular psychiatric medical records (“clinician history”), and data obtained by a genetic counsellor administering specific family psychiatric history questionnaires to patients and multiple family informants (“family history”) were compared using a kappa statistic. Good agreement between the two methods on the presence or absence of a psychiatric disorder was found among first-degree relatives of index cases, but poor agreement was found with respect to the presence or absence of a specific mood disorder diagnosis(es) in a relative. The results suggest that a clinician-generated family psychiatric history is sensitive to the presence or absence of a psychiatric disorder when compared to a more structured detailed genetic interview. However, for research purposes, a clinician-generated family psychiatric history of a specific mood disorder diagnosis, without supporting collateral information, may not be reliable for use in supporting a mood disorder diagnosis in a patient and/or his relatives.

scholarly journals Acute secondary mania due to amoxicillin use in a patient with family history of mood disorders

2011 ◽  
Vol 1 (2) ◽  
pp. 72
Author(s):  
Bahadir Bakim ◽  
Gokay Alpak ◽  
Hakan Sengul ◽  
Nilay Kahraman ◽  
Onur Tankaya ◽  
...  
Keyword(s):  
Family History ◽  
Mood Disorders ◽  
History Of ◽  
Secondary Mania

Family History of Suicidal Behavior and Mood Disorders in Probands With Mood Disorders

2005 ◽  
Vol 162 (9) ◽  
pp. 1672-1679 ◽  
Author(s):  
J. John Mann ◽  
Jonathan Bortinger ◽  
Maria A. Oquendo ◽  
Dianne Currier ◽  
Shuhua Li ◽  
...  
Keyword(s):  
Family History ◽  
Mood Disorders ◽  
Suicidal Behavior ◽  
History Of

scholarly journals Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND

2019 ◽  
Vol 91 (3) ◽  
pp. 245-253 ◽  
Author(s):  
Caroline A McHutchison ◽  
Danielle Jane Leighton ◽  
Andrew McIntosh ◽  
Elaine Cleary ◽  
Jon Warner ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Family History ◽  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Frontotemporal Dementia ◽  
Mood Disorders ◽  
Behavioural Change ◽  
Neuropsychiatric Disorders ◽  
Neuropsychiatric Disorder ◽  
History Of

ObjectiveIn this population-based study, we aimed to determine whether neuropsychiatric history, medication or family history of neuropsychiatric disorders predicted cognitive and/or behavioural impairment in motor neuron disease (MND).MethodsPeople with MND (pwMND) on the Scottish Clinical, Audit, Research and Evaluation of MND (CARE-MND) register, diagnosed from January 2015 to January 2018, with cognitive and/or behavioural data measured using the Edinburgh Cognitive and Behavioural ALS Screen were included. Data were extracted on patient neuropsychiatric, medication and family history of neuropsychiatric disorders. We identified patients with cognitive impairment (motor neuron disease with cognitive impairment (MNDci)), behavioural impairment (motor neuron disease with behavioural impairment (MNDbi), both (motor neuron disease with cognitive and behavioural impairment (MNDcbi)) or motor neuron disease–frontotemporal dementia (MND-FTD).ResultsData were available for 305 pwMND (mean age at diagnosis=62.26 years, SD=11.40), of which 60 (19.7%) had a neuropsychiatric disorder. A family history of neuropsychiatric disorders was present in 36/231 (15.58%) of patients. Patient premorbid mood disorders were associated with increased apathy (OR=2.78, 95% CI 1.083 to 7.169). A family history of any neuropsychiatric disorder was associated with poorer visuospatial scores, MNDbi (OR=3.14, 95% CI 1.09 to 8.99) and MND-FTD (OR=5.08, 95% CI 1.26 to 20.40). A family history of mood disorders was associated with poorer overall cognition (exp(b)=0.725, p=0.026), language, verbal fluency and visuospatial scores, and MND-FTD (OR=7.57, 95% CI 1.55 to 46.87). A family history of neurotic disorders was associated with poorer language (exp(b)=0.362, p<0.001), visuospatial scores (exp(b)=0.625, p<0.009) and MND-FTD (OR=13.75, 95% CI 1.71 to 110.86).ConclusionNeuropsychiatric disorders in patients and their families are associated with cognitive and behavioural changes post-MND diagnosis, with many occurring independently of MND-FTD and C9orf72 status. These findings support an overlap between MND, frontotemporal dementia and neuropsychiatric disorders, particularly mood disorders.

Family History of Mood Disorders is Associated With Lifetime Suicide Attempt in Patients With Bipolar Disorder

2020 ◽  
Vol 87 (9) ◽  
pp. S289
Author(s):  
Valeria Cuellar ◽  
Alexandre Paim Diaz ◽  
Flavio Silva ◽  
Elizabeth Vinson ◽  
Sudhakar Selvaraj ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Suicide Attempt ◽  
Mood Disorders ◽  
History Of

scholarly journals Predictors of postconcussion syndrome after sports-related concussion in young athletes: a matched case-control study

2015 ◽  
Vol 15 (6) ◽  
pp. 589-598 ◽  
Author(s):  
Clinton D. Morgan ◽  
Scott L. Zuckerman ◽  
Young M. Lee ◽  
Lauren King ◽  
Susan Beaird ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Mood Disorders ◽  
Psychiatric Illness ◽  
Case Control Study ◽  
Case Control ◽  
Young Athletes ◽  
History Of ◽  
Matched Case ◽  
Control Study

OBJECT Sport-related concussion (SRC) is a major public health problem. Approximately 90% of SRCs in high school athletes are transient; symptoms recover to baseline within 1 week. However, a small percentage of patients remain symptomatic several months after injury, with a condition known as postconcussion syndrome (PCS). The authors aimed to identify risk factors for PCS development in a cohort of exclusively young athletes (9–18 years of age) who sustained SRCs while playing a sport. METHODS The authors conducted a retrospective case-control study by using the Vanderbilt Sports Concussion Clinic database. They identified 40 patients with PCS and matched them by age at injury and sex to SRC control patients (1 PCS to 2 control). PCS patients were those experiencing persistent symptoms at 3 months after an SRC. Control patients were those with documented resolution of symptoms within 3 weeks of an SRC. Data were collected in 4 categories: 1) demographic variables; 2) key medical, psychiatric, and family history; 3) acute-phase postinjury symptoms (at 0–24 hours); and 4) subacute-phase postinjury features (at 0–3 weeks). The chi-square Fisher exact test was used to assess categorical variables, and the Mann-Whitney U-test was used to evaluate continuous variables. Forward stepwise regression models (Pin = 0.05, Pout = 0.10) were used to identify variables associated with PCS. RESULTS PCS patients were more likely than control patients to have a concussion history (p = 0.010), premorbid mood disorders (p = 0.002), other psychiatric illness (p = 0.039), or significant life stressors (p = 0.036). Other factors that increased the likelihood of PCS development were a family history of mood disorders, other psychiatric illness, and migraine. Development of PCS was not predicted by race, insurance status, body mass index, sport, helmet use, medication use, and type of symptom endorsement. A final logistic regression analysis of candidate variables showed PCS to be predicted by a history of concussion (OR 1.8, 95% CI 1.1–2.8, p = 0.016), preinjury mood disorders (OR 17.9, 95% CI 2.9–113.0, p = 0.002), family history of mood disorders (OR 3.1, 95% CI 1.1–8.5, p = 0.026), and delayed symptom onset (OR 20.7, 95% CI 3.2–132.0, p < 0.001). CONCLUSIONS In this age- and sex-matched case-control study of risk factors for PCS among youth with SRC, risk for development of PCS was higher in those with a personal and/or family history of mood disorders, other psychiatric illness, and migraine. These findings highlight the unique nature of SRC in youth. For this population, providers must recognize the value of establishing the baseline health and psychiatric status of children and their primary caregivers with regard to symptom reporting and recovery expectations. In addition, delayed symptom onset was an unexpected but strong risk factor for PCS in this cohort. Delayed symptoms could potentially result in late removal from play, rest, and care by qualified health care professionals. Taken together, these results may help practitioners identify young athletes with concussion who are at a greater danger for PCS and inform larger prospective studies for validation of risk factors from this cohort.

Multiple sclerosis and alcohol: a study of problem drinking

2004 ◽  
Vol 10 (2) ◽  
pp. 197-201 ◽  
Author(s):  
Susan Quesnel ◽  
Anthony Feinstein
Keyword(s):  
Multiple Sclerosis ◽  
Mental Illness ◽  
Family History ◽  
Suicidal Ideation ◽  
Mood Disorders ◽  
Problem Drinking ◽  
Positive Family History ◽  
Lifetime Prevalence ◽  
Increased Risk ◽  
History Of

Multiple sclerosis (MS) patients are known to be at increased risk from mood disorders and suicidal ideation. A lthough these are often associated with alcohol disorders, the drinking habits of MS patients have not been well studied to date. O ur study assessed drinking patterns in 140 MS patients, focusing on a possible link between problem drinking and mood and anxiety disorders. Lifetime psychiatric diagnoses were ascertained using the Structured C linical Interview for DSM-IV disorders (SCID-IV). Results demonstrate that one in six MS patients drink to excess over the course of their lifetime. Those with a history of problem drinking display a higher lifetime prevalence of anxiety (P =0.006), but not mood disorders. There were also significant associations between problem drinking and a lifetime prevalence of suicidal ideation (P =0.006), substance abuse (P =0.001), and a family history of mental illness (P =0.008). C linicians should be aware of the possibility of problem drinking in MS patients, and how this may complicate the course of their disease. C lues to problem drinking in MS patients are the presence of a positive family history of mental illness and prominent anxiety.

Association between family history of mood disorders and clinical characteristics of bipolar disorder: Results from the Brazilian bipolar research network

2014 ◽  
Vol 161 ◽  
pp. 104-108 ◽  
Author(s):  
Mariangeles Berutti ◽  
Fabiano G. Nery ◽  
Rodrigo Sato ◽  
Angela Scippa ◽  
Flavio Kapczinski ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Mood Disorders ◽  
Clinical Characteristics ◽  
Research Network ◽  
History Of

DSM outcomes of psychotic experiences and associated risk factors: 6-year follow-up study in a community-based sample

2018 ◽  
Vol 49 (08) ◽  
pp. 1346-1356 ◽  
Author(s):  
Umut Kırlı ◽  
Tolga Binbay ◽  
Marjan Drukker ◽  
Hayriye Elbi ◽  
Bülent Kayahan ◽  
...  
Keyword(s):  
Family History ◽  
Mood Disorders ◽  
Psychotic Disorder ◽  
Psychotic Disorders ◽  
Composite International Diagnostic Interview ◽  
Risk Indicator ◽  
Psychotic Experiences ◽  
Sampling Frame ◽  
History Of

AbstractBackgroundPsychotic experiences (PEs) may predict a range of common, non-psychotic disorders as well as psychotic disorders. In this representative, general population-based cohort study, both psychotic and non-psychotic disorder outcomes of PE were analysed, as were potential moderators.MethodsAddresses were contacted in a multistage clustered probability sampling frame covering 11 districts and 302 neighbourhoods at baseline (n = 4011). Participants were interviewed with the Composite International Diagnostic Interview (CIDI) both at baseline and at 6-year follow-up. Participants with PE at baseline were clinically re-interviewed with the SCID-I at follow-up. The role of socio-demographics, characteristics of PE, co-occurrence of mood disorders and family history of mental disorders were tested in the association between baseline PE and follow-up diagnosis.ResultsIn the participants with baseline PE, the psychotic disorder diagnosis rate at follow up was 7.0% – much lower than the rates of DSM-IV mood disorders without psychotic features (42.8%) and other non-psychotic disorders (24.1%). Within the group with baseline PE, female sex, lower socio-economic status, co-occurrence of mood disorders, family history of a mental disorder and persistence of PE predicted any follow-up DSM diagnosis. Furthermore, onset of psychotic v. non-psychotic disorder was predicted by younger age (15–30 years), co-presence of delusional and hallucinatory PE and family history of severe mental illness.ConclusionThe outcome of PE appears to be a consequence of baseline severity of multidimensional psychopathology and familial risk. It may be useful to consider PE as a risk indicator that has trans-diagnostic value.

Sign in / Sign up

Export Citation Format

Share Document