Family history of anxiety and mood disorders in anorexia nervosa: Review of the literature

2008 ◽  
Vol 13 (1) ◽  
pp. 1-13 ◽  
Author(s):  
F. Perdereau ◽  
S. Faucher ◽  
J. Wallier ◽  
S. Vibert ◽  
N. Godart
Keyword(s):  
Anorexia Nervosa ◽  
Family History ◽  
Mood Disorders ◽  
Review Of The Literature ◽  
History Of

Gallbladder Paraganglioma: A Case Report With Review of the Literature

2005 ◽  
Vol 129 (4) ◽  
pp. 523-526 ◽  
Author(s):  
Shveta Mehra ◽  
Moonja Chung-Park
Keyword(s):  
Case Report ◽  
Retrospective Study ◽  
Family History ◽  
Gastrointestinal Bleeding ◽  
Biliary System ◽  
Rare Tumor ◽  
Review Of The Literature ◽  
Quadrant Pain ◽  
Endocrine Neoplasia ◽  
History Of

Abstract We report a case of gallbladder paraganglioma that was discovered during nonrelated surgery. Retrospective study disclosed a family history of pheochromocytoma. The occurrence of gallbladder paraganglioma in the presence of family history of endocrine neoplasia supports that gallbladder paraganglioma may indeed occur as a part of the multiple endocrine neoplasm syndrome. Gallbladder paraganglioma is a rare tumor, and so far to our knowledge only 6 cases have been reported in the literature. Three cases were discovered incidentally during cholecystectomy for cholelithiasis, 2 presented with right upper quadrant pain, and 1 manifested with gastrointestinal bleeding. We herein review all reported cases of paraganglioma of gallbladder and biliary system.

Obtaining a Family Psychiatric History: Is it Worth the Effort?

1993 ◽  
Vol 38 (9) ◽  
pp. 590-594 ◽  
Author(s):  
Ronald A. Remick ◽  
Adele D. Sadovnick ◽  
Boris Gimbarzevsky ◽  
Raymond W. Lam ◽  
Athanasios P. Zis ◽  
...  
Keyword(s):  
Family History ◽  
Psychiatric Disorder ◽  
Mood Disorder ◽  
Mood Disorders ◽  
Medical Records ◽  
Psychiatric History ◽  
First Degree Relatives ◽  
History Of ◽  
Generated Family ◽  
Index Cases

The purpose of this study was to determine whether, for first-degree relatives of patients presenting to a mood disorders clinic, family history information on psychiatric conditions collected by a psychiatrist and incorporated into the patient's medical records is as informative as that gathered during an interview specifically designed to collect family history data. The study group consisted of 472 first-degree relatives of 78 randomly selected index cases from a large mood disorders genetic database. Family history of psychiatric disorders recorded in regular psychiatric medical records (“clinician history”), and data obtained by a genetic counsellor administering specific family psychiatric history questionnaires to patients and multiple family informants (“family history”) were compared using a kappa statistic. Good agreement between the two methods on the presence or absence of a psychiatric disorder was found among first-degree relatives of index cases, but poor agreement was found with respect to the presence or absence of a specific mood disorder diagnosis(es) in a relative. The results suggest that a clinician-generated family psychiatric history is sensitive to the presence or absence of a psychiatric disorder when compared to a more structured detailed genetic interview. However, for research purposes, a clinician-generated family psychiatric history of a specific mood disorder diagnosis, without supporting collateral information, may not be reliable for use in supporting a mood disorder diagnosis in a patient and/or his relatives.

scholarly journals Acute secondary mania due to amoxicillin use in a patient with family history of mood disorders

2011 ◽  
Vol 1 (2) ◽  
pp. 72
Author(s):  
Bahadir Bakim ◽  
Gokay Alpak ◽  
Hakan Sengul ◽  
Nilay Kahraman ◽  
Onur Tankaya ◽  
...  
Keyword(s):  
Family History ◽  
Mood Disorders ◽  
History Of ◽  
Secondary Mania

scholarly journals Increased anticipatory but decreased consummatory brain responses to food in sisters of anorexia nervosa patients

BJPsych Open ◽  
2016 ◽  
Vol 2 (4) ◽  
pp. 255-261 ◽  
Author(s):  
Stefanie Horndasch ◽  
Sophie O'Keefe ◽  
Anneka Lamond ◽  
Katie Brown ◽  
Ciara McCabe
Keyword(s):  
Anorexia Nervosa ◽  
Family History ◽  
Neural Response ◽  
Anterior Cingulate ◽  
Neural Responses ◽  
Food Cues ◽  
Dorsal Anterior Cingulate Cortex ◽  
Brain Responses ◽  
History Of ◽  
Increased Activity

BackgroundWe have previously shown increased anticipatory and consummatory neural responses to rewarding and aversive food stimuli in women recovered from anorexia nervosa (AN).AimsTo determine whether these differences are trait markers for AN, we examined the neural response in those with a familial history but no personal history of AN.MethodThirty-six volunteers were recruited: 15 who had a sister with anorexia nervosa (family history) and 21 control participants. Using fMRI we examined the neural response during an anticipatory phase (food cues, rewarding and aversive), an effort phase and a consummatory phase (rewarding and aversive tastes).ResultsFamily history (FH) volunteers showed increased activity in the caudate during the anticipation of both reward and aversive food and in the thalamus and amygdala during anticipation of aversive only. FH had decreased activity in the dorsal anterior cingulate cortex, the pallidum and the superior frontal gyrus during taste consumption.ConclusionsIncreased neural anticipatory but decreased consummatory responses to food might be a biomarker for AN. Interventions that could normalise these differences may help to prevent disorder onset.

Lithium in a Case of Severe Anorexia Nervosa

1982 ◽  
Vol 140 (5) ◽  
pp. 526-528 ◽  
Author(s):  
G. S. Stein ◽  
S. Hartshorn ◽  
J. Jones ◽  
D. Steinberg
Keyword(s):  
Anorexia Nervosa ◽  
Depressive Symptoms ◽  
Family History ◽  
Affective Disorder ◽  
Complex Relationship ◽  
Psychological Treatments ◽  
Treatment Of Depression ◽  
History Of

Anorexia nervosa may sometimes be resistant to all forms of therapy, with cases running through a gamut of somatic and psychological treatments. One possible explanation for this may be that the illness is of heterogeneous aetiology (Kay and Leigh, 1938; King, 1963; Feighner et al, 1972), although others regard anorexia as a single condition that tends to breed true though having protean manifestations (Russell, 1970; Crisp et al, 1980). In most of the larger series of cases, a proportion have depressive symptoms both during the illness (Dally, 1969; Theander, 1970; Crisp et al, 1980) and some years later (Morgan and Russell, 1975; Hsu et al, 1979), and a family history of affective disorder is also commonly reported (Dally, 1969; Theander, 1970; Morgan and Russell, 1975). Cantwell et al (1977) have reviewed the complex relationship between depression and anorexia nervosa and have suggested that some of the remedies used in the treatment of depression merit further exploration in the management of anorexia nervosa. We report here a patient who was in hospital for over four years and in whose eventual improvement lithium may have played an important role.

Investigation of ‘weight pathology’ of 58 mothers of anorexia nervosa patients and 204 mothers of schoolgirls

1986 ◽  
Vol 16 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Anne Hall ◽  
Julie Leibrich ◽  
Frank H. Walkey ◽  
Gary Welch
Keyword(s):  
Socioeconomic Status ◽  
Anorexia Nervosa ◽  
Family History ◽  
Eating Behaviour ◽  
Family Factors ◽  
Weight History ◽  
History Of ◽  
Weight Watchers ◽  
Current Weight

Synopsis‘Weight pathology’ – defined by Kalucy et al. (1977) as ‘deviations in weight, shape, eating behaviour and activity’ – has been hypothesized to be unduly common in families with anorexia nervosa. It was investigated in this study by means of questionnaires evaluating both weight history and attitudes towards weight-related matters in 58 mothers of anorexia nervosa patients and 204 mothers of schoolgirls of similar age and socioeconomic status (SES). No support was found for the hypothesis. A family history of aberrant weight and mother's current weight and past weight histories showed no significant differences between the groups. 142 other mothers of schoolchildren and 446 attenders at Weight Watchers also completed the questionnaire on attitudes towards weight-related matters. Mothers of patients showed a lower concern on all scales than did all other groups. The findings are discussed in relation to earlier controlled studies of family factors in anorexia nervosa.

Family History of Suicidal Behavior and Mood Disorders in Probands With Mood Disorders

2005 ◽  
Vol 162 (9) ◽  
pp. 1672-1679 ◽  
Author(s):  
J. John Mann ◽  
Jonathan Bortinger ◽  
Maria A. Oquendo ◽  
Dianne Currier ◽  
Shuhua Li ◽  
...  
Keyword(s):  
Family History ◽  
Mood Disorders ◽  
Suicidal Behavior ◽  
History Of

scholarly journals Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND

2019 ◽  
Vol 91 (3) ◽  
pp. 245-253 ◽  
Author(s):  
Caroline A McHutchison ◽  
Danielle Jane Leighton ◽  
Andrew McIntosh ◽  
Elaine Cleary ◽  
Jon Warner ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Family History ◽  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Frontotemporal Dementia ◽  
Mood Disorders ◽  
Behavioural Change ◽  
Neuropsychiatric Disorders ◽  
Neuropsychiatric Disorder ◽  
History Of

ObjectiveIn this population-based study, we aimed to determine whether neuropsychiatric history, medication or family history of neuropsychiatric disorders predicted cognitive and/or behavioural impairment in motor neuron disease (MND).MethodsPeople with MND (pwMND) on the Scottish Clinical, Audit, Research and Evaluation of MND (CARE-MND) register, diagnosed from January 2015 to January 2018, with cognitive and/or behavioural data measured using the Edinburgh Cognitive and Behavioural ALS Screen were included. Data were extracted on patient neuropsychiatric, medication and family history of neuropsychiatric disorders. We identified patients with cognitive impairment (motor neuron disease with cognitive impairment (MNDci)), behavioural impairment (motor neuron disease with behavioural impairment (MNDbi), both (motor neuron disease with cognitive and behavioural impairment (MNDcbi)) or motor neuron disease–frontotemporal dementia (MND-FTD).ResultsData were available for 305 pwMND (mean age at diagnosis=62.26 years, SD=11.40), of which 60 (19.7%) had a neuropsychiatric disorder. A family history of neuropsychiatric disorders was present in 36/231 (15.58%) of patients. Patient premorbid mood disorders were associated with increased apathy (OR=2.78, 95% CI 1.083 to 7.169). A family history of any neuropsychiatric disorder was associated with poorer visuospatial scores, MNDbi (OR=3.14, 95% CI 1.09 to 8.99) and MND-FTD (OR=5.08, 95% CI 1.26 to 20.40). A family history of mood disorders was associated with poorer overall cognition (exp(b)=0.725, p=0.026), language, verbal fluency and visuospatial scores, and MND-FTD (OR=7.57, 95% CI 1.55 to 46.87). A family history of neurotic disorders was associated with poorer language (exp(b)=0.362, p<0.001), visuospatial scores (exp(b)=0.625, p<0.009) and MND-FTD (OR=13.75, 95% CI 1.71 to 110.86).ConclusionNeuropsychiatric disorders in patients and their families are associated with cognitive and behavioural changes post-MND diagnosis, with many occurring independently of MND-FTD and C9orf72 status. These findings support an overlap between MND, frontotemporal dementia and neuropsychiatric disorders, particularly mood disorders.

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