Behavioral Aspects of Genetic Risk for Disease: Cancer Genetics as a Prototype for Complex Issues in Health Psychology.

2004 ◽  
pp. 115-142
Author(s):  
Lari Wenzel ◽  
Karen Glanz
Keyword(s):  
Health Psychology ◽  
Genetic Risk ◽  
Cancer Genetics ◽  
Behavioral Aspects

Ethical Obligations and Counseling Challenges in Cancer Genetics

2006 ◽  
Vol 4 (2) ◽  
pp. 185-191 ◽  
Author(s):  
Wylie Burke ◽  
Nancy Press
Keyword(s):  
Genetic Risk ◽  
Cancer Genetics ◽  
Accurate Information ◽  
Family Risk ◽  
Delivery Of Care ◽  
Duty To Warn ◽  
The Face ◽  
Practice Opportunities ◽  
Risk Reduction Measures ◽  
Ethical Obligations

Cancer genetics is creating new practice opportunities in medical genetics, oncology, and primary care. The ethical and counseling challenges of this new area of practice are not unique but sometimes take new form in the context of genetic risk. This article uses cases to explore the issues associated with shared family risk, including competing concerns of family members, duty to warn relatives of genetic risk, and testing of children and other relatives. The ethical obligations of clinicians start with the need to maintain competence in the face of rapidly evolving science. Clinicians should be able to identify patients within their practice who are candidates for genetic testing. When genetic susceptibility to cancer is identified, patients should be offered counseling and follow-up, with referral as appropriate, to ensure delivery of care consistent with current standards. When patients experience barriers to needed health care, clinicians should advocate for their needs. Clinicians must ensure the autonomy and informed decision-making of all members of cancer-prone families. Clinicians must also provide emotional support and accurate information about cancer risks and cancer risk reduction measures, including uncertainties. Teamwork among different specialties is important in addressing these challenges.

scholarly journals Cloning of the genes for non-medullary thyroid cancer: Methods and advances

2006 ◽  
Vol 14 (1-2) ◽  
pp. 30-34
Author(s):  
Karmen Stankov ◽  
Giovanni Romeo
Keyword(s):  
Thyroid Cancer ◽  
Molecular Biology ◽  
Somatic Cell ◽  
Genetic Risk ◽  
Medullary Thyroid Cancer ◽  
Germ Line ◽  
Cancer Genetics ◽  
Genetic Changes ◽  
Medullary Thyroid ◽  
New Genes

In last ten years, significant advances have occurred in thyroid endocrinology, as a consequence of the generalized use of molecular biology techniques. New genes involved in the development of thyroid cancer have been identified, which had a great impact on our understanding of thyroid cancer predisposition. All cancers are genetic in origin because they arise from mutations in a single somatic cell, but the genetic changes in sporadic cancers are confined to a particular tissue. In inherited cancers, a predisposing mutation is present in all somatic cells and in the germ line, which enables the transmission of risk to the next generation. Cancer genetics offers a model of how information on the genetics of inherited cancers could affect identification of individuals at increased genetic risk.

scholarly journals Electronic health records contain dispersed risk factor information that could be used to prevent breast and ovarian cancer

2020 ◽  
Vol 27 (9) ◽  
pp. 1443-1449
Author(s):  
Thomas H Payne ◽  
Lue Ping Zhao ◽  
Calvin Le ◽  
Peter Wilcox ◽  
Troy Yi ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Risk Factor ◽  
Genetic Risk ◽  
Risk Evaluation ◽  
Cancer Genetics ◽  
National Guidelines ◽  
Breast And Ovarian Cancer ◽  
Information Meeting ◽  
Electronic Health ◽  
Risk Factor Information

Abstract Objective The genetic testing for hereditary breast cancer that is most helpful in high-risk women is underused. Our objective was to quantify the risk factors for heritable breast and ovarian cancer contained in the electronic health record (EHR), to determine how many women meet national guidelines for referral to a cancer genetics professional but have no record of a referral. Methods and Materials We reviewed EHR records of a random sample of women to determine the presence and location of risk-factor information meeting National Comprehensive Cancer Network (NCCN) guidelines for a further genetic risk evaluation for breast and/or ovarian cancer, and determine whether the women were referred for such an evaluation. Results A thorough review of the EHR records of 299 women revealed that 24 (8%) met the NCCN criteria for referral for a further genetic risk evaluation; of these, 12 (50%) had no referral to a medical genetics clinic. Conclusions Half of the women whose EHR records contain risk-factor information meeting the criteria for further genetic risk evaluation for heritable forms of breast and ovarian cancer were not referred.

Health psychology and health promotion

2008 ◽  
Vol 16 (3) ◽  
pp. 123-126 ◽  
Author(s):  
Toni Faltermaier
Keyword(s):  
Health Psychology ◽  
Health Promotion ◽  
Health Resources ◽  
Target Groups ◽  
Occupational Groups ◽  
Socially Disadvantaged ◽  
Research Activities ◽  
Health And Illness ◽  
Prevention And Health Promotion ◽  
Basic And Applied Research

Abstract. The Flensburg health psychology group takes a salutogenic perspective and aims at developing innovative health promotion approaches. It stands in the interdisciplinary context of health and educational sciences. Our focus in research is on both, stress processes and lay representations of health and illness in the context of salutogenic theories of health. Basic and applied research activities aim at developing subject-oriented approaches of prevention and health promotion that are designed to promote health resources and competencies in selected settings and target groups. Current research is concentrated on socially disadvantaged groups, on occupational groups and on men to develop tailored health promotion approaches that reach groups in need and which show sustainable effects.

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