Selection of Patients from the Clinical Point of View.

2006 ◽  
pp. 372-389 ◽  
Author(s):  
F. A. Freyhan
Keyword(s):  
Point Of View ◽  
Clinical Point ◽  
Selection Of Patients ◽  
Selection Of

Pharmacogenetic Testing in Nephrological Clinic

2016 ◽  
pp. 83-86
Author(s):  
D. Ivanov ◽  
A. Melnik
Keyword(s):  
Drug Response ◽  
Antihypertensive Drugs ◽  
Antihypertensive Agents ◽  
Point Of View ◽  
First Line ◽  
Pharmacogenetic Testing ◽  
Clinical Point ◽  
Slow Metabolizers ◽  
Selection Of

Selection of antihypertensive agents using pharmacogenetic tests and individual tolerance is essential in nephrology. Antihypertensive drugs are metabolized first line through various isoforms CYP (CYP2D6, CYP2C9, CYP2C19 and CYP3A4/5). These isoforms are the most significant for the patient in response to drug response. From a clinical point of view, it is important to establish the slow metabolizers (poor metabolism, PM), because it is they need to use other doses of antihypertensive drugs that different from the standard.

scholarly journals The Future of Stem Cells and Their Derivates in the Treatment of Glaucoma. A Critical Point of View

2021 ◽  
Vol 22 (20) ◽  
pp. 11077
Author(s):  
Simona Delia Nicoară ◽  
Ioana Brie ◽  
Ancuța Jurj ◽  
Olga Sorițău
Keyword(s):  
Stem Cells ◽  
Optic Nerve ◽  
Animal Studies ◽  
High Capacity ◽  
Point Of View ◽  
Cell Therapies ◽  
Stem Cells Transplantation ◽  
Action Methods ◽  
Selection Of Patients ◽  
Selection Of

This review focuses on the clinical translation of preclinical studies, especially those that have used stem cells in the treatment of glaucoma, with an emphasis on optic nerve regeneration. The studies referred to in the review aim to treat optic nerve atrophy, while cell therapies targeting other sites in the eye, such as the trabecular meshwork, have not been addressed. Such complex and varied pathophysiological mechanisms that lead to glaucoma may explain the fact that although stem cells have a high capacity of neuronal regeneration, the treatments performed did not have the expected results and the promise offered by animal studies was not achieved. By analyzing the facts associated with failure, important lessons are to be learned: the type of stem cells that are used, the route of administration, the selection of patients eligible for these treatments, additional therapies that support stem cells transplantation and their mode of action, methods of avoiding the host’s immune response. Many of these problems could be solved using exosomes (EV), but also miRNA, which allows more targeted approaches with minimal side effects.

scholarly journals Features of anesthesia in pregnant women with subarachnoid hemorrhages

2013 ◽  
Vol 94 (1) ◽  
pp. 89-95
Author(s):  
A Z Bayalieva ◽  
R Y Shpaner ◽  
E I Bogdanova ◽  
I R Ganeeva
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Pregnant Women ◽  
Treatment Options ◽  
Systolic Pressure ◽  
Point Of View ◽  
Oxygen Intake ◽  
Review Of The Literature ◽  
Clinical Point ◽  
Subarachnoid Hemorrhages ◽  
Selection Of

The review of the literature on anesthesia in pregnant women with subarachnoid hemorrhage is presented. Physiological changes of pregnancy should by undoubtedly taken into consideration while performing anesthesia and surgery because of the comorbidities. Particularly, the oxygen intake is higher in pregnant. Adequate systolic pressure is also a very important parameter maintaining the intrauterine blood flow and fetus perfusion during the whole term of pregnancy. Medications used in pregnant women can also influence the fetus. From the clinical point of view, the selection of anesthetics and other medications allowed for use in pregnant women should be limited to medications that are proven to be safe. Pharmacological effects of the medications, used for anesthesia and treatment of pregnant women with subarachnoid hemorrhage are covered in the review, including their influence on fetus. Surgical treatment options for pregnant women at different pregnancy terms with different conditions requiring neurosurgery are surveyed. Post-surgical rehabilitation of pregnant women with subarachnoid hemorrhage is reviewed. In each particular clinical case an individual anesthesia plan should be created considering the pregnancy term and features of the disease.

scholarly journals PENDEKATAN SOSIAL DALAM PENELITIAN KESEHATAN REPRODUKSI

Populasi ◽  
2016 ◽  
Vol 6 (2) ◽  
Author(s):  
Rosalia Sciortino
Keyword(s):  
Family Planning Program ◽  
Reproductive Behaviour ◽  
Point Of View ◽  
Gender Relation ◽  
Planning Program ◽  
Cultural Research ◽  
Clinical Point ◽  
The Right ◽  
Goals And Objectives ◽  
Selection Of

Population problems, particularly fertility and family planning program, used to be approached from a clinical instead of socio-culture perspectives. A clinical point of view never involves through aspect of reproductive right thought; which includes the right of any individuals (men and women) and couples (husband-wife) in making decisions in terms of reproductive behaviour along their reproductive ages. In this regard, this paper states that reproductive healthproblems should be understood from a social perspective. This is because reproductive health problems is cause and influence social, political,and economic system as well as gender relation. Therefore, the selection of the appropriate social - cultural research methods/approaches is undoubtedly needed. Methodology should be developed appropriately to meet the research goals and objectives.

Some Observations on Renal Function in Mental Disorder

1936 ◽  
Vol 82 (338) ◽  
pp. 242-253 ◽  
Author(s):  
B. H. Shaw
Keyword(s):  
Renal Function ◽  
Mental Disorder ◽  
Renal Dysfunction ◽  
Point Of View ◽  
Clear Cut ◽  
Clinical Type ◽  
Clinical Point ◽  
Selection Of

Renal dysfunction is so commonly present in cases of mental breakdown that it is of interest to know whether it is especially associated with any definite clinical type or types of mental disorder. In an endeavour to ascertain this, cases have been selected from recent admissions in which the form of disorder from a clinical point of view appeared to be sufficiently marked to warrant placing them in a definite category. Many cases present such a mixture of cycloid, schizoid, confusional or paranoid indications that in an investigation of this nature the selection of sufficiently clear-cut types from a clinical standpoint is not altogether an easy matter. To determine the degree of concentration and polyuria, Rosenberg's modification of the Volhard test has been adopted. It involves little discomfort to the patient and is as follows:—

Selection of patients for portal-systemic shunts

JAMA ◽  
1966 ◽  
Vol 196 (12) ◽  
pp. 1039-1044 ◽  
Author(s):  
R. E. Hermann
Keyword(s):  
Selection Of Patients ◽  
Selection Of

Tauchnitz for Translators. The Circulation of English-language Literature in Finland

2019 ◽  
Vol 16 (2-3) ◽  
pp. 161-179
Author(s):  
Outi Paloposki
Keyword(s):  
Foreign Language ◽  
English Language ◽  
Book History ◽  
Language Skills ◽  
Point Of View ◽  
Book Production ◽  
German Publisher ◽  
Language Literature ◽  
Selection Of

The article looks at book production and circulation from the point of view of translators, who, as purchasers and readers of foreign-language books, are an important mediating force in the selection of literature for translation. Taking the German publisher Tauchnitz's series ‘Collection of British Authors’ and its circulation in Finland in the nineteenth and early twentieth century as a case in point, the article argues that the increased availability of English-language books facilitated the acquiring and honing of translators' language skills and gradually diminished the need for indirect translating. Book history and translation studies meet here in an examination of the role of the Collection in Finnish translators' work.

Perioperative acute internal carotid thrombosis after general surgery

2020 ◽  
Vol 99 (3) ◽  
pp. 136-140
Keyword(s):  
Cardiac Surgery ◽  
Internal Carotid ◽  
Right Hemicolectomy ◽  
Diagnostic Assessment ◽  
Left Carotid Artery ◽  
Perioperative Stroke ◽  
Internal Carotid Occlusion ◽  
Acute Brain Ischemia ◽  
Selection Of Patients ◽  
Selection Of

Introduction: The average incidence of perioperative stroke during major non-cardiac surgery is less than 1%, suggesting that it is rarely a major problem for the vast majority of patients. Methods: In our paper we present a 46-year-old patient undergoing acute right hemicolectomy who developed right-sided hemiparesis in the perioperative setting. Immediate CTAg examination showed an ischemic stroke in the left hemisphere as a result of left internal carotid thrombosis. A surgical procedure to recanalize the left carotid artery was performed 14 hours from the onset of neurological symptomatology and the neurological deficit gradually recovered fully. Conclusion: Our case report supports studies showing that a thorough diagnostic assessment allows the selection of patients who may benefit from urgent revascularization of acute internal carotid occlusion during the phase of acute brain ischemia.

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