Behavior genetic studies of change.

Author(s):  
John Loehlin
2020 ◽  
Author(s):  
Nicole Barbaro

Attachment theory has strong environmental origins, from which it has been the broad consensus that variation in attachment is caused by variation in environments (shared and non-shared), with little role of genetic variation, especially in infants. However, the state of the behavior genetic evidence needs critical evaluation to discern whether such environmentalist claims are warranted. Here, I demonstrate that the majority of the available twin studies are not adequately powered to detect additive genetic effects if present, and that the majority of twin studies in infants are not adequately powered to detect shared environmental effects. Within the published research, I can find only three adequately powered twin studies on attachment: one in infants, one in adolescents, and one in adults. I conclude by presenting five observations from behavior genetic studies that future developmental frameworks of attachment must account for.


2015 ◽  
Vol 141 (4) ◽  
pp. 769-785 ◽  
Author(s):  
Tena Vukasović ◽  
Denis Bratko

VASA ◽  
2015 ◽  
Vol 44 (5) ◽  
pp. 333-340 ◽  
Author(s):  
Christian Werner ◽  
Ulrich Laufs

Abstract. Summary: The term “LDL hypothesis” is frequently used to describe the association of low-density lipoprotein cholesterol (LDL-cholesterol, LDL-C) and cardiovascular (CV) events. Recent data from genetic studies prove a causal relation between serum LDL-C and CV events. These data are in agreement with mechanistic molecular studies and epidemiology. New randomised clinical trial data show that LDL-C lowering with statins and a non-statin drug, ezetimibe, reduces CV events. We therefore believe that the “LDL-hypothesis” has been proven; the term appears to be outdated and should be replaced by “LDL causality”.


2009 ◽  
Vol 42 (05) ◽  
Author(s):  
H Konnerth ◽  
I Giegling ◽  
AM Hartmann ◽  
J Genius ◽  
A Ruppert ◽  
...  

1969 ◽  
Vol 08 (01) ◽  
pp. 07-11 ◽  
Author(s):  
H. B. Newcombe

Methods are described for deriving personal and family histories of birth, marriage, procreation, ill health and death, for large populations, from existing civil registrations of vital events and the routine records of ill health. Computers have been used to group together and »link« the separately derived records pertaining to successive events in the lives of the same individuals and families, rapidly and on a large scale. Most of the records employed are already available as machine readable punchcards and magnetic tapes, for statistical and administrative purposes, and only minor modifications have been made to the manner in which these are produced.As applied to the population of the Canadian province of British Columbia (currently about 2 million people) these methods have already yielded substantial information on the risks of disease: a) in the population, b) in relation to various parental characteristics, and c) as correlated with previous occurrences in the family histories.


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