Characterization of submicron aerosol size distributions from time-resolved measurements in the Atlantic Stratocumulus Transition Experiment/Marine Aerosol and Gas Exchange

1996 ◽  
Vol 101 (D2) ◽  
pp. 4469-4478 ◽  
Author(s):  
Lynn M. Russell ◽  
Barry J. Huebert ◽  
Richard C. Flagan ◽  
John H. Seinfeld
Keyword(s):  
Gas Exchange ◽  
Size Distributions ◽  
Marine Aerosol ◽  
Time Resolved ◽  
Submicron Aerosol ◽  
Time Resolved Measurements

Time-resolved measurements of the cluster-size distributions arising in charge-heteroaggregation processes

2004 ◽  
pp. 151-154 ◽  
Author(s):  
J. M. López-López ◽  
A. Schmitt ◽  
J. Callejas-Fernández ◽  
R. Hidalgo-Álvarez
Keyword(s):  
Cluster Size ◽  
Size Distributions ◽  
Time Resolved ◽  
Time Resolved Measurements

scholarly journals Characterization of Valley Winter Woodsmoke Concentrations in Northern NY Using Highly Time-Resolved Measurements

2011 ◽  
Vol 11 (5) ◽  
pp. 519-530 ◽  
Author(s):  
George A. Allen ◽  
Paul J. Miller ◽  
Lisa J. Rector ◽  
Michael Brauer ◽  
Jason G. Su
Keyword(s):  
Time Resolved ◽  
Time Resolved Measurements

CHARACTERIZATION OF PORE SIZE DISTRIBUTIONS USING NON-NEWTONIAN FLUIDS

2020 ◽  
Author(s):  
Scott C. Hauswirth ◽  
◽  
Majdi Abou Najm ◽  
Christelle Basset
Keyword(s):  
Pore Size ◽  
Newtonian Fluids ◽  
Size Distributions ◽  
Pore Size Distributions

scholarly journals Size-resolved characterization of organic aerosol in the North China Plain: new insights from high resolution spectral analysis

2021 ◽  
Author(s):  
Weiqi Xu ◽  
Chun Chen ◽  
Yanmei Qiu ◽  
Conghui Xie ◽  
Yunle Chen ◽  
...  
Keyword(s):  
Radiative Forcing ◽  
North China Plain ◽  
North China ◽  
Fine Particles ◽  
Large Fraction ◽  
Organic Aerosol ◽  
Size Distributions ◽  
The North ◽  
The Impact

Organic aerosol (OA), a large fraction of fine particles, has a large impact on climate radiative forcing and human health, and the impact depends strongly on size distributions. Here we...

scholarly journals Characterization of a Novel FRET Probe in a Crowded Environment using Time-Resolved Anisotropy

2017 ◽  
Vol 112 (3) ◽  
pp. 346a
Author(s):  
Hannah Leopold ◽  
Megan Currie ◽  
Jacob Schwarz ◽  
Arnold J. Boersma ◽  
Erin D. Sheets ◽  
...  
Keyword(s):  
Time Resolved ◽  
Crowded Environment

scholarly journals Characterization of submicron aerosol particles in winter at Albany, New York

2022 ◽  
Vol 111 ◽  
pp. 118-129
Author(s):  
Xiuli Wei ◽  
Huaqiao Gui ◽  
Jianguo Liu ◽  
Ying Cheng
Keyword(s):  
New York ◽  
Aerosol Particles ◽  
Submicron Aerosol

scholarly journals KD determination from time-resolved experiments on live cells with LigandTracer and reconciliation with end-point flow cytometry measurements

2021 ◽  
Author(s):  
Diana Spiegelberg ◽  
Jonas Stenberg ◽  
Pascale Richalet ◽  
Marc Vanhove
Keyword(s):  
Flow Cytometry ◽  
Live Cells ◽  
Time Resolved ◽  
Surface Receptors ◽  
Full Characterization ◽  
End Point ◽  
Titration Curves ◽  
Kinetics Of

AbstractDesign of next-generation therapeutics comes with new challenges and emulates technology and methods to meet them. Characterizing the binding of either natural ligands or therapeutic proteins to cell-surface receptors, for which relevant recombinant versions may not exist, represents one of these challenges. Here we report the characterization of the interaction of five different antibody therapeutics (Trastuzumab, Rituximab, Panitumumab, Pertuzumab, and Cetuximab) with their cognate target receptors using LigandTracer. The method offers the advantage of being performed on live cells, alleviating the need for a recombinant source of the receptor. Furthermore, time-resolved measurements, in addition to allowing the determination of the affinity of the studied drug to its target, give access to the binding kinetics thereby providing a full characterization of the system. In this study, we also compared time-resolved LigandTracer data with end-point KD determination from flow cytometry experiments and hypothesize that discrepancies between these two approaches, when they exist, generally come from flow cytometry titration curves being acquired prior to full equilibration of the system. Our data, however, show that knowledge of the kinetics of the interaction allows to reconcile the data obtained by flow cytometry and LigandTracer and demonstrate the complementarity of these two methods.

scholarly journals Time-Resolved Spectroscopic Study of N,N-Di(4-bromo)nitrenium Ions in Selected Solutions

Molecules ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 3182 ◽  
Author(s):  
Lili Du ◽  
Xin Lan ◽  
Zhiping Yan ◽  
Ruixue Zhu ◽  
David Phillips
Keyword(s):  
Transient Absorption ◽  
Direct Detection ◽  
Reaction Pathway ◽  
Addition Reactions ◽  
Time Resolved ◽  
Nitrenium Ions ◽  
Future Studies ◽  
Nitrenium Ion ◽  
Design Time

Nitrenium ions are important reactive intermediates in chemistry and biology. In this work, femtosecond and nanosecond transient absorption (fs-TA and ns-TA) along with nanosecond time-resolved resonance Raman (ns-TR3) experiments were employed to examine the photochemical pathways of N-(4,4′-dibromodiphenylamino)-2,4,6-trimethylpyridinium BF4− (salt (DN) from just absorption of a photon of light to the production of the important N,N-di(4-bromophenyl)nitrenium ion 2. In acetonitrile (MeCN), the formation of halogenated diarylnitrenium ion 2 was observed within 4 ps, showing the vibrational spectra with strong intensity. The nucleophilic adduct reaction of ion 2 with H2O was also examined in aqueous solutions. The direct detection of the unique ortho adduct intermediate 3 shows that there is an efficient and exclusive reaction pathway for 2 with H2O. The results shown in this paper give new characterization of 2, which can be used to design time-resolved spectroscopy investigations of covalent addition reactions of nitrenium ions with other molecules in future studies.

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