Metabolic Activation of Racemic and Enantiomerictrans-8,9-Dihydroxy-8,9-dihydrodibenzo[a,l]pyrene (Dibenzo[def,p]chrysene) to Dibenzo[a,l]pyrene-bis-dihydrodiols by Induced Rat Liver Microsomes and a Recombinant Human P450 1A1 System:  The Role of the K-Region-Derived Metabolic Intermediates in the Formation of Dibenzo[a,l]pyrene−DNA Adducts†

1998 ◽  
Vol 11 (12) ◽  
pp. 1596-1607 ◽  
Author(s):  
Stephen Nesnow ◽  
Christine Davis ◽  
William Padgett ◽  
Michael George ◽  
Guy Lambert ◽  
...  
Keyword(s):  
Rat Liver ◽  
Dna Adducts ◽  
Liver Microsomes ◽  
Metabolic Activation ◽  
Rat Liver Microsomes ◽  
Metabolic Intermediates

Metabolic activation of hydralazine by rat liver microsomes

1987 ◽  
Vol 36 (16) ◽  
pp. 2667-2672 ◽  
Author(s):  
Lynn B. LaCagnin ◽  
Howard D. Colby ◽  
Naresh S. Dalal ◽  
John P. O'Donnell
Keyword(s):  
Rat Liver ◽  
Liver Microsomes ◽  
Metabolic Activation ◽  
Rat Liver Microsomes

Metabolic activation of 1,2,4-trichlorobenzene and pentachlorobenzene by rat liver microsomes: A major role for quinone metabolites

1991 ◽  
Vol 108 (2) ◽  
pp. 223-233 ◽  
Author(s):  
Cathaline den Besten ◽  
Marjan C.C. Smink ◽  
Erik J. de Vries ◽  
Peter J. van Bladeren
Keyword(s):  
Rat Liver ◽  
Liver Microsomes ◽  
Metabolic Activation ◽  
Rat Liver Microsomes

Oxidation of methyl- and ethyl- tertiary-butyl ethers in rat liver microsomes: role of the cytochrome P450 isoforms

1998 ◽  
Vol 72 (4) ◽  
pp. 207-214 ◽  
Author(s):  
Alessandra Turini ◽  
Giada Amato ◽  
Vincenzo Longo ◽  
Pier Giovanni Gervasi
Keyword(s):  
Cytochrome P450 ◽  
Rat Liver ◽  
Liver Microsomes ◽  
Rat Liver Microsomes ◽  
Tertiary Butyl ◽  
Cytochrome P450 Isoforms
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