Mechanism of Formation of (Deoxy)guanosine Adducts Derived from Peroxidase-Catalyzed Oxidation of the Carcinogenic Nonaminoazo Dye 1-Phenylazo-2-hydroxynaphthalene (Sudan I)

2009 ◽  
Vol 22 (11) ◽  
pp. 1765-1773 ◽  
Author(s):  
Martin Dračínský ◽  
Josef Cvačka ◽  
Marcela Semanská ◽  
Václav Martínek ◽  
Eva Frei ◽  
...  
Keyword(s):  
Mechanism Of Formation ◽  
Sudan I ◽  
Catalyzed Oxidation

NADH oxidation during peroxidase catalyzed metabolism of carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I)

1990 ◽  
Vol 55 (9) ◽  
pp. 2321-2327 ◽  
Author(s):  
Marie Stiborová ◽  
Pavel Anzenbacher
Keyword(s):  
Nucleic Acids ◽  
Chemical Carcinogenesis ◽  
Point Of View ◽  
Nadh Oxidation ◽  
Physiological Significance ◽  
Reactive Metabolite ◽  
Sudan I ◽  
Catalyzed Oxidation

The peroxidase catalyzed oxidation of 1-phenylazo-2-hydroxynaphthalene (Sudan I) in the presence of NADH results in oxidation to oxidized NAD+. This oxidation is supposed to be caused by the reduction of reactive Sudan I metabolite(s). Under certain conditions NADH acts as the agent protecting the cellular nucleophilic compounds such as nucleic acids (DNA, tRNA) against modification caused by reactive metabolite(s) formed from carcinogenic Sudan I by the peroxidase/H2O2 system. The results are discussed from the point of view of the physiological significance of NADH in the initiation of chemical carcinogenesis.

Renilla Bioluminescence: A Morphologic Approach to the Location of Photocytes

1974 ◽  
Vol 32 ◽  
pp. 208-209
Author(s):  
Ben O. Spurlock ◽  
Milton J. Cormier
Keyword(s):  
Excited State ◽  
Ground State ◽  
Molecular Basis ◽  
Light Emission ◽  
Chemical Basis ◽  
Electronic Excited State ◽  
Colonial Form ◽  
The Common ◽  
Eighteenth And Nineteenth Centuries ◽  
Catalyzed Oxidation

The phenomenon of bioluminescence has fascinated layman and scientist alike for many centuries. During the eighteenth and nineteenth centuries a number of observations were reported on the physiology of bioluminescence in Renilla, the common sea pansy. More recently biochemists have directed their attention to the molecular basis of luminosity in this colonial form. These studies have centered primarily on defining the chemical basis for bioluminescence and its control. It is now established that bioluminescence in Renilla arises due to the luciferase-catalyzed oxidation of luciferin. This results in the creation of a product (oxyluciferin) in an electronic excited state. The transition of oxyluciferin from its excited state to the ground state leads to light emission.

Regarding the mechanism of formation of nonmetallic inclusions conglomerates of system Al2O3-MgO

2019 ◽  
Vol 75 (12) ◽  
pp. 1341-1351
Author(s):  
A. A. Safronov ◽  
V. S. Dub ◽  
V. V. Orlov ◽  
K. L. Kosyrev ◽  
A. S. Loskutov ◽  
...  
Keyword(s):  
Nonmetallic Inclusions ◽  
Mechanism Of Formation

Assessment of ability to varnish turbine oils

2020 ◽  
Vol 06 ◽  
pp. 28-33
Author(s):  
I.V. Mitin ◽  
◽  
I.R. Tatur ◽  
K.U. Smirnov ◽  
A.M. Suloev ◽  
...  
Keyword(s):  
Antioxidant Properties ◽  
Mechanism Of Formation ◽  
Critical Situation ◽  
Antioxidant Content ◽  
Turbine Equipment

The reasons for the formation of varnish deposits of turbine oils are determined. It is shown that the performance of turbine oils is determined by methods of ASTM D7843 (MPC) and ASTM D6971 (RUL) can be assessed, the process of formation of varnish deposits, the level of antioxidant properties, antioxidant content of, amend, and extend the oil change, and to predict critical situation in the operation of turbine equipment. The mechanism of formation of varnish deposits in turbine oils is proposed.

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