Effects of Glutathione on Alkylation and Crosslinking of DNA by Mitomycin C. Isolation of a Ternary Glutathione-Mitomycin-DNA Adduct

Mrinalni Sharma; Qiao-Yun He; Maria Tomasz

doi:10.1021/tx00039a018

Effects of Glutathione on Alkylation and Crosslinking of DNA by Mitomycin C. Isolation of a Ternary Glutathione-Mitomycin-DNA Adduct

Chemical Research in Toxicology ◽

10.1021/tx00039a018 ◽

1994 ◽

Vol 7 (3) ◽

pp. 401-407 ◽

Cited By ~ 19

Author(s):

Mrinalni Sharma ◽

Qiao-Yun He ◽

Maria Tomasz

Keyword(s):

Mitomycin C ◽

Dna Adduct

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Synthesis of a major mitomycin C DNA adduct via a triaminomitosene

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2012.09.052 ◽

2012 ◽

Vol 22 (23) ◽

pp. 7198-7200 ◽

Cited By ~ 5

Author(s):

Elise Champeil ◽

Manuel M. Paz ◽

Elaan Lukasiewicz ◽

Wan S. Kong ◽

Stephanie Watson ◽

...

Keyword(s):

Mitomycin C ◽

Dna Adduct

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2,7-Diaminomitosene, a Monofunctional Mitomycin C Derivative, Alkylates DNA in the Major Groove. Structure and Base-Sequence Specificity of the DNA Adduct and Mechanism of the Alkylation

Journal of the American Chemical Society ◽

10.1021/ja9607401 ◽

1996 ◽

Vol 118 (39) ◽

pp. 9209-9217 ◽

Cited By ~ 31

Author(s):

Gopinatha Suresh Kumar ◽

Steven M. Musser ◽

Jeffrey Cummings ◽

Maria Tomasz

Keyword(s):

Mitomycin C ◽

Dna Adduct ◽

Base Sequence ◽

Sequence Specificity ◽

Major Groove ◽

Groove Structure

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ChemInform Abstract: 2,7-Diaminomitosene (I), a Monofunctional Mitomycin C Derivative, Alkylates DNA in the Major Groove. Structure and Base-Sequence Specificity of the DNA Adduct and Mechanism of the Alkylation.

ChemInform ◽

10.1002/chin.199703295 ◽

2010 ◽

Vol 28 (3) ◽

pp. no-no

Author(s):

G. S. KUMAR ◽

S. M. MUSSER ◽

J. CUMMINGS ◽

M. TOMASZ

Keyword(s):

Mitomycin C ◽

Dna Adduct ◽

Base Sequence ◽

Sequence Specificity ◽

Major Groove ◽

Groove Structure

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DNA Adduct of the Mitomycin C Metabolite 2,7-Diaminomitosene Is a Nontoxic and Nonmutagenic DNA Lesion in Vitro and in Vivo

Chemical Research in Toxicology ◽

10.1021/tx049813h ◽

2005 ◽

Vol 18 (2) ◽

pp. 213-223 ◽

Cited By ~ 9

Author(s):

Christopher D. Utzat ◽

Cristina C. Clement ◽

Leilani A. Ramos ◽

Arunangshu Das ◽

Maria Tomasz ◽

...

Keyword(s):

Mitomycin C ◽

Dna Adduct ◽

Dna Lesion

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DNA adduct formation of mitomycin C. A test case for DFT calculations on model systems

Computational and Theoretical Chemistry ◽

10.1016/j.comptc.2012.10.022 ◽

2013 ◽

Vol 1005 ◽

pp. 9-15 ◽

Cited By ~ 2

Author(s):

Paul A. Hume ◽

Margaret A. Brimble ◽

Jóhannes Reynisson

Keyword(s):

Dft Calculations ◽

Mitomycin C ◽

Adduct Formation ◽

Dna Adduct ◽

Model Systems ◽

Test Case

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1570: Combined Mitomycin C and Hyperthermia (SYNERGO) for Patients with Superficial Bladder Cancer (SBC) after Bacillus Calmette-Guerin (BCG) Failure

The Journal of Urology ◽

10.1016/s0022-5347(18)31758-0 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 519-519

Author(s):

Ofer Nativ ◽

Renzo Colombo ◽

Dov Engelstein ◽

Ofer N. Gofrit ◽

Thomas Akkad ◽

...

Keyword(s):

Bladder Cancer ◽

Mitomycin C ◽

Superficial Bladder Cancer ◽

Bacillus Calmette Guerin ◽

Bcg Failure

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832: Optimized Intravesical Mitomycin C Treatment for Superficial Bladder Cancer: Long-Term Follow-Up

The Journal of Urology ◽

10.1016/s0022-5347(18)33068-4 ◽

2006 ◽

Vol 175 (4S) ◽

pp. 268-269 ◽

Cited By ~ 3

Author(s):

Jessie L. Au ◽

Robert A. Badalament ◽

M. Guillaume Wientjes ◽

Donn C. Young ◽

Tong Shen ◽

...

Keyword(s):

Bladder Cancer ◽

Mitomycin C ◽

Superficial Bladder Cancer ◽

Long Term Follow Up

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In vitro antigenotoxic studies of Thai noni fruit juice (Morinda citrifolia L., Rubiacecae) against a chemotherapeutic agent, mitomycin c, in human lymphocytes

Planta Medica ◽

10.1055/s-0028-1084302 ◽

2008 ◽

Vol 74 (09) ◽

Cited By ~ 1

Author(s):

T Ratanavalachai ◽

S Thitiorul ◽

P Nandhasri

Keyword(s):

Mitomycin C ◽

Fruit Juice ◽

Chemotherapeutic Agent ◽

Human Lymphocytes ◽

Morinda Citrifolia

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Erste Ergebnisse – Die gedeckte Sklerotomie unter primärer Anwendung von Mitomycin C 0,02%

Klinische Monatsblätter für Augenheilkunde ◽

10.1055/s-0028-1110059 ◽

2008 ◽

Vol 225 (S 04) ◽

Author(s):

E Karioris ◽

C Wirbelauer ◽

H Häberle ◽

DT Pham

Keyword(s):

Mitomycin C ◽

Erste Ergebnisse

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Lokale Applikation von Mitomycin C bei Atemwegsstenosen

Pneumologie ◽

10.1055/s-0029-1213906 ◽

2009 ◽

Vol 63 (S 01) ◽

Author(s):

PC Bauer ◽

U Sommerwerck ◽

J Hagmeyer ◽

F Bonella ◽

U Costabel

Keyword(s):

Mitomycin C

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