2,7-Diaminomitosene, a Monofunctional Mitomycin C Derivative, Alkylates DNA in the Major Groove. Structure and Base-Sequence Specificity of the DNA Adduct and Mechanism of the Alkylation

1996 ◽  
Vol 118 (39) ◽  
pp. 9209-9217 ◽  
Author(s):  
Gopinatha Suresh Kumar ◽  
Steven M. Musser ◽  
Jeffrey Cummings ◽  
Maria Tomasz
Keyword(s):  
Mitomycin C ◽  
Dna Adduct ◽  
Base Sequence ◽  
Sequence Specificity ◽  
Major Groove ◽  
Groove Structure

Reaction of the antitumor antibiotic CC-1065 with DNA: structure of a DNA adduct with DNA sequence specificity

Science ◽  
1984 ◽  
Vol 226 (4676) ◽  
pp. 843-844 ◽  
Author(s):  
L. Hurley ◽  
V. Reynolds ◽  
D. Swenson ◽  
G. Petzold ◽  
T. Scahill
Keyword(s):  
Dna Sequence ◽  
Dna Structure ◽  
Dna Adduct ◽  
Antitumor Antibiotic ◽  
Sequence Specificity ◽  
Dna Sequence Specificity

Synthesis of a major mitomycin C DNA adduct via a triaminomitosene

2012 ◽  
Vol 22 (23) ◽  
pp. 7198-7200 ◽  
Author(s):  
Elise Champeil ◽  
Manuel M. Paz ◽  
Elaan Lukasiewicz ◽  
Wan S. Kong ◽  
Stephanie Watson ◽  
...  
Keyword(s):  
Mitomycin C ◽  
Dna Adduct

Base sequence specificity of three 2-chloroethylnitrosoureas

1990 ◽  
Vol 40 (6) ◽  
pp. 1201-1209 ◽  
Author(s):  
William T. Briscoe ◽  
Steven P. Anderson ◽  
Hubert E. May
Keyword(s):  
Base Sequence ◽  
Sequence Specificity

Structure of a Site Specific Major Groove (2S,3S)-N6-(2,3,4-Trihydroxybutyl)-2‘-deoxyadenosyl DNA Adduct of Butadiene Diol Epoxide

2004 ◽  
Vol 17 (6) ◽  
pp. 717-730 ◽  
Author(s):  
Tandace A. Scholdberg ◽  
Lubomir V. Nechev ◽  
W. Keither Merritt ◽  
Thomas M. Harris ◽  
Constance M. Harris ◽  
...  
Keyword(s):  
Dna Adduct ◽  
Major Groove ◽  
Site Specific ◽  
Diol Epoxide ◽  
A Site

scholarly journals Sequence specificity of Cr(III)–DNA adduct formation in the p53 gene: NGG sequences are preferential adduct-forming sites

2005 ◽  
Vol 27 (3) ◽  
pp. 639-645 ◽  
Author(s):  
Hirohumi Arakawa ◽  
Feng Wu ◽  
Max Costa ◽  
William Rom ◽  
Moon-shong Tang
Keyword(s):  
P53 Gene ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Sequence Specificity

scholarly journals Molecular Dynamics Investigations on Base Sequence Specificity of Counterion Binding to DNA

2012 ◽  
Vol 102 (3) ◽  
pp. 637a
Author(s):  
Alessio Atzori ◽  
Sonia Liggi ◽  
Aatto Laaksonen ◽  
Alexander Lyubartsev ◽  
Giuseppe Saba ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Base Sequence ◽  
Sequence Specificity ◽  
Counterion Binding
Sign in / Sign up

Export Citation Format

Share Document