Expression in Escherichia coli of the flavin-containing monooxygenase D (form II) from adult human liver: Determination of a distinct tertiary amine substrate specificity

1993 ◽  
Vol 6 (4) ◽  
pp. 425-429 ◽  
Author(s):  
Noureddine Lomri ◽  
Zicheng Yang ◽  
John R. Cashman
1987 ◽  
Vol 243 (3) ◽  
pp. 859-861 ◽  
Author(s):  
J E A Leakey ◽  
R Hume ◽  
B Burchell

UDP-glucuronyltransferase activities towards eight substrates were assayed in samples of foetal, term and adult human liver. Activities towards bilirubin, androsterone, testosterone, 1-naphthol, 4-nitrophenol and 2-aminophenol were present in foetal and term liver samples at less than 14% of adult values, whereas activity towards 5-hydroxytryptamine was present in foetal and term liver at 109 and 121% of adult values respectively. Thus a ‘foetal’ form of UDP-glucuronyltransferase may exist in human liver that is more restricted in substrate specificity than are those of the rat or rhesus monkey.


2013 ◽  
Vol 51 (01) ◽  
Author(s):  
N Fekete-Drimusz ◽  
J de la Roche ◽  
F Vondran ◽  
CL Sajti ◽  
MP Manns ◽  
...  

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