scholarly journals Multiplex Targeted Proteomic Assay for Biomarker Detection in Plasma: A Pancreatic Cancer Biomarker Case Study

2012 ◽  
Vol 11 (3) ◽  
pp. 1937-1948 ◽  
Author(s):  
Sheng Pan ◽  
Ru Chen ◽  
Randall E. Brand ◽  
Sarah Hawley ◽  
Yasuko Tamura ◽  
...  
2019 ◽  
Vol 13 (2) ◽  
pp. 105-121 ◽  
Author(s):  
Yan Wang ◽  
Keke Liu ◽  
Qin Ma ◽  
Yongfei Tan ◽  
Wei Du ◽  
...  

The Analyst ◽  
2020 ◽  
Vol 145 (15) ◽  
pp. 5113-5117 ◽  
Author(s):  
K. Sudhakara Prasad ◽  
Yousef Abugalyon ◽  
Chunqiang Li ◽  
Feng Xu ◽  
XiuJun Li

Catalytic properties of gold nanoparticles in colour dye degradation are utilized to amplify colorimetric detection signals of a low-cost paper-based immunosensor for instrument-free detection of pancreatic cancer biomarker PEAK1.


2021 ◽  
Vol 255 ◽  
pp. 13003
Author(s):  
Tommaso Pileri ◽  
Alberto Sinibaldi ◽  
Agostino Occhicone ◽  
Elena Giordani ◽  
Matteo Allegretti ◽  
...  

An optical biosensor for proteomic breast cancer biomarker detection in complex media is presented. Bloch Surface Waves (BSW) excited onto one dimensional photonic crystal (1DPC) were used to probe the interaction of HER2 with three antibody species and an inert protein (Bovine Serum Albumin - BSA). The optical system combines Label-Free readings to track the bioassay real-time development and Fluorescence emission quantification to evaluate the level of specific interaction between the antigen and the antibodies. The results confirm a distinguishable level of affinity between the antibodies and the analyte according to their specificity even at low antibody surface density (about 1173 pg/mm2).


2018 ◽  
Vol 545 ◽  
pp. 13-19 ◽  
Author(s):  
Sajid Rauf ◽  
Geetesh K. Mishra ◽  
Jahanzaib Azhar ◽  
Rupesh K. Mishra ◽  
K. Yugender Goud ◽  
...  

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