H Ferritin Gene Silencing in a Human Metastatic Melanoma Cell Line: A Proteomic Analysis

2011 ◽  
Vol 10 (12) ◽  
pp. 5444-5453 ◽  
Author(s):  
Maddalena Di Sanzo ◽  
Marco Gaspari ◽  
Roberta Misaggi ◽  
Francesco Romeo ◽  
Lucia Falbo ◽  
...  
Keyword(s):  
Gene Silencing ◽  
Metastatic Melanoma ◽  
Cell Line ◽  
Melanoma Cell ◽  
Proteomic Analysis ◽  
Melanoma Cell Line ◽  
Metastatic Melanoma Cell ◽  
Ferritin Gene

Establishment of a novel Chinese metastatic melanoma cell line showing the new cytogenetic and biological properties

2015 ◽  
Vol 39 (4) ◽  
pp. 508-514
Author(s):  
Xiuli Yi ◽  
Guannan Zhu ◽  
Yan Li ◽  
Ying Liu ◽  
Qi Luan ◽  
...  
Keyword(s):  
Metastatic Melanoma ◽  
Cell Line ◽  
Melanoma Cell ◽  
Melanoma Cell Line ◽  
Biological Properties ◽  
Metastatic Melanoma Cell

In-vitro study of the influence of octocrylene on a selected metastatic melanoma cell line

2019 ◽  
Vol 154 (2) ◽  
Author(s):  
Tanja Prunk Zdravković ◽  
Bogdan Zdravković ◽  
Marko Zdravković ◽  
Barbara Dariš ◽  
Mojca Lunder ◽  
...  
Keyword(s):  
Metastatic Melanoma ◽  
Cell Line ◽  
Melanoma Cell ◽  
Melanoma Cell Line ◽  
In Vitro Study ◽  
Vitro Study ◽  
Metastatic Melanoma Cell

scholarly journals Standard melanoma-associated markers do not identify the MM127 metastatic melanoma cell line

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Parvathi Haridas ◽  
Jacqui A. McGovern ◽  
Abhishek S. Kashyap ◽  
D. L. Sean McElwain ◽  
Matthew J. Simpson
Keyword(s):  
Metastatic Melanoma ◽  
Cell Line ◽  
Melanoma Cell ◽  
Melanoma Cell Line ◽  
Metastatic Melanoma Cell

Establishment and characterization of a primary and a metastatic melanoma cell line from Grey horses

2013 ◽  
Vol 50 (1) ◽  
pp. 56-65 ◽  
Author(s):  
Monika H. Seltenhammer ◽  
Elisabeth Sundström ◽  
Claudia Meisslitzer-Ruppitsch ◽  
Petra Cejka ◽  
Jedrzej Kosiuk ◽  
...  
Keyword(s):  
Metastatic Melanoma ◽  
Cell Line ◽  
Melanoma Cell ◽  
Melanoma Cell Line ◽  
Metastatic Melanoma Cell

scholarly journals Antiproliferative Activity of Selected Triterpene Acids from Rosemary on Metastatic Melanoma Cell Line WM-266-4

2021 ◽  
Vol 9 (B) ◽  
pp. 515-521
Author(s):  
Suzana Isaković-Vidović ◽  
Barbara Dariš ◽  
Željko Knez ◽  
Kristina Vidović ◽  
Dejan Oprić ◽  
...  
Keyword(s):  
Metastatic Melanoma ◽  
Cell Line ◽  
Incubation Period ◽  
Melanoma Cell ◽  
Melanoma Cell Line ◽  
Metastatic Melanoma Cell ◽  
Triterpene Acids ◽  
Wide Range ◽  
Triterpenic Acids ◽  
Proliferation Activity

BACKGROUND: Natural products and their derivatives, particularly secondary metabolites, have been recognized for many years as an important source of therapeutic agents. In this context, pentacyclic triterpene acids including betulinic acid (BA), oleanolic acid (OA), and ursolic acid (UA) are highly valuable triterpenic acids because of their wide range of biological activities. AIM: Therefore, the aim of our study was to investigate any potential effect of BA, UA, and OA on human melanoma WM-266-4 cells’ proliferation activity. METHODS: BA, UA, and OA have been prepared in dimethyl sulfoxide in concentration range from 0.002 to 200 μM separately or in selected combination (UA+OA ratio 1:1 or 3.5:1), while cells in cell culture medium served as controls. The rapid colorimetric MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay was used to measure proliferation activity of the metastatic melanoma cell line WM-266-4 after being exposed to selected concentrations of BA, UA, OA, or UA+OA and during different time periods. Student’s t-test was used for single statistical comparisons. Data were analyzed using IBM SPSS 25.0 (IBM Corp., Armonk, NY). To account for multiple comparisons bias, p < 0.001 was considered statistically significant. RESULTS: Our results showed decreased cell proliferation activity after 4 h of incubation of WM-266-4 cells with BA, UA, OA, and UA+OA. The highest inhibitory effect was noted when cells were incubated with selected triterpenic acids and both combinations of UA+OA during the incubation period of 48 h. When compared to control cells, concentration of 2 μM was the lowest concentration of BA that showed a significant decrease of the cells’ proliferation activity regardless the incubation period (4 h, 24 h, and 48 h) (p < 0.001). CONCLUSION: Our encouraging results could be a good starting point for further studies on possible use of BA, UA, and OA in prevention and treatment of metastatic melanoma.

Immunotherapy with dendritic cells primed with an allogenic melanoma cell line in advanced metastatic melanoma

2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 20026-20026
Author(s):  
J. Nesselhut ◽  
D. Marx ◽  
R. Y. Chang ◽  
C. Matthes ◽  
D. Lorenzen ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Metastatic Melanoma ◽  
Cell Line ◽  
Melanoma Cell ◽  
Melanoma Cell Line

scholarly journals Quantitative proteomic analysis for radiation-induced cell cycle suspension in 92-1 melanoma cell line

2013 ◽  
Vol 54 (4) ◽  
pp. 649-662 ◽  
Author(s):  
Fengling Wang ◽  
Zhitong Bing ◽  
Yanan Zhang ◽  
Bin Ao ◽  
Sheng Zhang ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Line ◽  
Melanoma Cell ◽  
Proteomic Analysis ◽  
Melanoma Cell Line ◽  
Quantitative Proteomic Analysis ◽  
Radiation Induced
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