Trade-Off between High Sensitivity and Increased Potential for False Positive Peptide Sequence Matches Using a Two-Dimensional Linear Ion Trap for Tandem Mass Spectrometry-Based Proteomics

2006 ◽  
Vol 5 (4) ◽  
pp. 1003-1009 ◽  
Author(s):  
Hongwei Xie ◽  
Timothy J. Griffin
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
False Positive ◽  
Ion Trap ◽  
High Sensitivity ◽  
Peptide Sequence ◽  
Linear Ion Trap ◽  
Tandem Mass ◽  
Two Dimensional ◽  
Trade Off

scholarly journals Mycotoxin Incidence in Some Fish Products: QuEChERS Methodology and Liquid Chromatography Linear Ion Trap Tandem Mass Spectrometry Approach

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 527 ◽  
Author(s):  
Josefa Tolosa ◽  
Francisco Barba ◽  
Guillermina Font ◽  
Emilia Ferrer
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Ion Trap ◽  
Raw Materials ◽  
Fish Farming ◽  
Linear Ion Trap ◽  
Tandem Mass ◽  
Fish Products ◽  
Fish Samples

The inclusion of vegetal raw materials in feed for fish farming has increased the risk of mycotoxin occurrence in feed, as well as in edible tissues from fish fed with contaminated feed, due to the carry-over to muscle portions. Therefore, the objective of this study was to evaluate the occurrence of 15 mycotoxins in processed fish products, which are commonly consumed, such as smoked salmon and trout, different types of sushi, and gula substitutes. A QuEChERS method was employed to perform the mycotoxin extraction from fish samples. For mycotoxin identification and quantitation, the selected technique was the liquid chromatography-tandem mass spectrometry linear ion trap (LC-MS/MS-LIT). Smoked fish and sushi samples results were negative regarding the presence of all 15 mycotoxins studied. In contrast, small amounts of fusarenon-X and enniatin B were found in gula substitute samples.

Two-Dimensional Tandem Mass Spectrometry in a Single Scan on a Linear Quadrupole Ion Trap

2019 ◽  
Vol 91 (21) ◽  
pp. 13752-13762 ◽  
Author(s):  
Dalton T. Snyder ◽  
Lucas J. Szalwinski ◽  
Zachary St. John ◽  
R. Graham Cooks
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Ion Trap ◽  
Quadrupole Ion Trap ◽  
Tandem Mass ◽  
Two Dimensional ◽  
Linear Quadrupole Ion Trap
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