From High-Throughput Catalyst Screening to Reaction Optimization:  Detailed Investigation of Regioselective Suzuki Coupling of 1,6-Naphthyridone Dichloride

2007 ◽  
Vol 11 (3) ◽  
pp. 328-335 ◽  
Author(s):  
Chaoxian Cai ◽  
John Y. L. Chung ◽  
J. Christopher McWilliams ◽  
Yongkui Sun ◽  
C. Scott Shultz ◽  
...  
Keyword(s):  
High Throughput ◽  
Suzuki Coupling ◽  
Catalyst Screening ◽  
Reaction Optimization

Unlocking the Potential of High-Throughput Experimentation for Electrochemistry with a Standardized Microscale Reactor

2021 ◽  
Author(s):  
Jonas Rein ◽  
James R. Annand ◽  
Michael K. Wismer ◽  
Jiantao Fu ◽  
Juno C. Siu ◽  
...  
Keyword(s):  
High Throughput ◽  
Electrochemical Reaction ◽  
Electrochemical Reactor ◽  
Constant Current ◽  
Library Synthesis ◽  
Chemical Library ◽  
Reaction Discovery ◽  
Reaction Optimization ◽  
High Throughput Experimentation ◽  
Broad Array

Organic electrochemistry has emerged as an enabling and sustainable technology in modern organic synthesis. Despite the recent renaissance of electrosynthesis, the broad adoption of electrochemistry in the synthetic community and, especially in industrial settings, has been hindered by the dearth of general, standardized platforms for high-throughput experimentation (HTE). Herein, we disclose the design of the HT<i>e<sup>-</sup></i>Chem, a high-throughput microscale electrochemical reactor that is compatible with existing HTE infrastructure, and enables rapid evaluation of a broad array of electrochemical reaction parameters. Utilizing the HT<i>e<sup>-</sup></i>Chem to accelerate reaction optimization, reaction discovery, and chemical library synthesis is illustrated using a suite of oxidative and reductive transformations under constant current, constant voltage, and electrophotochemical conditions.

Discovery and evaluation of highly active imidotitanium ethylene polymerisation catalysts using high throughput catalyst screening

2004 ◽  
pp. 434-435 ◽  
Author(s):  
Nico Adams ◽  
Henricus J. Arts ◽  
Paul D. Bolton ◽  
Dan Cowell ◽  
Stuart R. Dubberley ◽  
...  
Keyword(s):  
High Throughput ◽  
Highly Active ◽  
Catalyst Screening ◽  
Ethylene Polymerisation

New Catalysts and Conditions for a CH Insertion Reaction Identified by High Throughput Catalyst Screening

1996 ◽  
Vol 35 (2) ◽  
pp. 220-222 ◽  
Author(s):  
Kevin Burgess ◽  
Hee-Jong Lim ◽  
Alexander M. Porte ◽  
Gary A. Sulikowski
Keyword(s):  
High Throughput ◽  
Insertion Reaction ◽  
Catalyst Screening

Robotic Lepidoptery: Structural Characterization of (mostly) Unexpected Palladium Complexes Obtained from High-Throughput Catalyst Screening

2009 ◽  
Vol 28 (17) ◽  
pp. 5017-5024 ◽  
Author(s):  
John E. Bercaw ◽  
Michael W. Day ◽  
Suzanne R. Golisz ◽  
Nilay Hazari ◽  
Lawrence M. Henling ◽  
...  
Keyword(s):  
High Throughput ◽  
Structural Characterization ◽  
Palladium Complexes ◽  
Catalyst Screening
Sign in / Sign up

Export Citation Format

Share Document