Application of Focused Microwaves to the Scale-Up of Solvent-Free Organic Reactions

2000 ◽  
Vol 4 (6) ◽  
pp. 498-504 ◽  
Author(s):  
J. Cléophax ◽  
M. Liagre ◽  
A. Loupy ◽  
A. Petit
Keyword(s):  
Scale Up ◽  
Solvent Free ◽  
Organic Reactions

scholarly journals Phase Behavior that Enables Solvent-Free Carbonate-Promoted Furoate Carboxylation

2020 ◽  
Author(s):  
Amy Frankhouser ◽  
Matthew Kanan
Keyword(s):  
Phase Behavior ◽  
Process Design ◽  
Heterogeneous Reaction ◽  
Scale Up ◽  
Solvent Free

<div><div><div><p>A solvent-free transformation that enables production of polyester precursors from inedible biomass proceeds from a heterogeneous reaction mixture containing both solid and molten components. Characterization of the evolution of these component phases over the course of the reaction provides insight relevant to process design and scale-up.</p></div></div></div>

Studies on the thermal coking of bitumen. I. The use of pyrene-d10 as a probe for evaluating the extent of hydrogen shuttling reaction

1991 ◽  
Vol 69 (1) ◽  
pp. 116-120 ◽  
Author(s):  
M. J. Kirk ◽  
T. S. Sorensen
Keyword(s):  
Free Radicals ◽  
Key Words ◽  
Hydrogen Exchange ◽  
Solvent Free ◽  
Hydrogen Donor ◽  
Organic Reactions ◽  
Hydrogen Atoms ◽  
Donor Solvent ◽  
Key Words Bitumen

The organic reactions that take place during the thermal coking of bitumen are extremely complex and deep-seated, but obviously hydrogen atoms originally attached to carbons that form coke will have moved to a new carbon site (net addition of hydrogen, resulting in upgraded bitumen). Accompanying this process, one expects some general hydrogen shuttling between non-coking molecules. This paper describes an approach to determing the extent of this latter process by the addition of a small amount of perdeuterated pyrene to the bitumen prior to the coking operation. The in situ pyrene functions as in indicator, allowing one to establish the extent and other mechanistic details of the "hydrogen donor" reactions that take place during coking. There is no indication that the pyrene substantially modifies the normal course of the reaction, hence the analogy to an indicator. Key words: bitumen coking, pyrene, hydrogen exchange, donor solvent, free radicals.

Environmentally Friendly Organic Synthesis Using Bismuth Compounds. Bismuth Trifluoromethanesulfonate-Catalyzed Allylation of Dioxolanes

2008 ◽  
Vol 61 (6) ◽  
pp. 419 ◽  
Author(s):  
Matthew J. Spafford ◽  
James E. Christensen ◽  
Matthew G. Huddle ◽  
Joshua R. Lacey ◽  
Ram S. Mohan
Keyword(s):  
Organic Synthesis ◽  
Multicomponent Reaction ◽  
Scale Up ◽  
Environmentally Friendly ◽  
Solvent Free ◽  
Bismuth Compounds ◽  
Solvent Free Conditions ◽  
In Situ Derivatization

A bismuth trifluoromethanesulfonate (triflate)-catalyzed (2.0 mol-%) multicomponent reaction involving the allylation of dioxolanes followed by in situ derivatization with anhydrides to generate highly functionalized esters has been developed under solvent-free conditions. Most reagents used to date for allylation of dioxolanes are highly corrosive and are often required in stoichiometric amounts. In contrast, the use of a relatively non-toxic and non-corrosive bismuth(iii)-based catalyst makes this methodology especially attractive for scale-up.

ChemInform Abstract: Solvent-Free Microwave-Assisted Organic Reactions. Preparation of β-Keto Esters.

ChemInform ◽  
2010 ◽  
Vol 31 (34) ◽  
pp. no-no
Author(s):  
Massimo Gianotti ◽  
Giorgio Martelli ◽  
Giuseppe Spunta ◽  
Eileen Campana ◽  
Mauro Panunzio ◽  
...  
Keyword(s):  
Solvent Free ◽  
Organic Reactions ◽  
Keto Esters ◽  
Microwave Assisted

scholarly journals Organic synthesis by Twin Screw Extrusion (TSE): continuous, scalable and solvent-free

2017 ◽  
Vol 19 (6) ◽  
pp. 1507-1518 ◽  
Author(s):  
Deborah E. Crawford ◽  
Clodagh K. G. Miskimmin ◽  
Ahmad B. Albadarin ◽  
Gavin Walker ◽  
Stuart L. James
Keyword(s):  
Organic Synthesis ◽  
Solvent Free ◽  
Pure Form ◽  
Organic Reactions ◽  
Twin Screw Extrusion ◽  
Continuous Basis ◽  
Screw Extrusion ◽  
Twin Screw ◽  
Work Up

Several organic reactions have been achieved quantitatively without any added solvent, using solid or liquid reagents, on a continuous basis; products are typically obtained directly in analytically pure form, requiring no work-up.

scholarly journals Phase Behavior that Enables Solvent-Free Carbonate-Promoted Furoate Carboxylation

2020 ◽  
Author(s):  
Amy Frankhouser ◽  
Matthew Kanan
Keyword(s):  
Phase Behavior ◽  
Process Design ◽  
Heterogeneous Reaction ◽  
Scale Up ◽  
Solvent Free

<div><div><div><p>A solvent-free transformation that enables production of polyester precursors from inedible biomass proceeds from a heterogeneous reaction mixture containing both solid and molten components. Characterization of the evolution of these component phases over the course of the reaction provides insight relevant to process design and scale-up.</p></div></div></div>

ChemInform Abstract: Solvent-Free Organic Reactions Using Microwaves: Applications in the Synthesis of Heterocyclic Compounds

ChemInform ◽  
2010 ◽  
Vol 30 (13) ◽  
pp. no-no
Author(s):  
Rajender S. Varma ◽  
Dalip Kumar ◽  
Rajender Dahiya ◽  
Per J. Liesen
Keyword(s):  
Heterocyclic Compounds ◽  
Solvent Free ◽  
Organic Reactions
Sign in / Sign up

Export Citation Format

Share Document