Iridium-Promoted Conversion of Chlorosilanes to Alkynyl Derivatives in a One-Pot Reaction Sequence

2014 ◽  
Vol 33 (12) ◽  
pp. 3051-3059 ◽  
Author(s):  
Ireneusz Kownacki ◽  
Bartosz Orwat ◽  
Bogdan Marciniec
Keyword(s):  
Reaction Sequence ◽  
One Pot

scholarly journals Appel-reagent-mediated transformation of glycosyl hemiacetal derivatives into thioglycosides and glycosyl thiols

2013 ◽  
Vol 9 ◽  
pp. 974-982 ◽  
Author(s):  
Tamashree Ghosh ◽  
Abhishek Santra ◽  
Anup Kumar Misra
Keyword(s):  
Reaction Sequence ◽  
Reaction Conditions ◽  
One Pot ◽  
Carbon Tetrabromide

A series of glycosyl hemiacetal derivatives have been transformed into thioglycosides and glycosyl thiols in a one-pot two-step reaction sequence mediated by Appel reagent (carbon tetrabromide and triphenylphosphine). 1,2-trans-Thioglycosides and β-glycosyl thiol derivatives were stereoselectively formed by the reaction of the in situ generated glycosyl bromides with thiols and sodium carbonotrithioate. The reaction conditions are reasonably simple and yields were very good.

Recycle Waste Salt as Reagent: A One-Pot Substitution/Krapcho Reaction Sequence to α-Fluorinated Esters and Sulfones

2015 ◽  
Vol 17 (4) ◽  
pp. 972-975 ◽  
Author(s):  
Feng Zhu ◽  
Peng-Wei Xu ◽  
Feng Zhou ◽  
Cui-Hong Wang ◽  
Jian Zhou
Keyword(s):  
Reaction Sequence ◽  
One Pot ◽  
Waste Salt

ChemInform Abstract: Three-Component, One-Pot Diastereoselective Synthesis of 4-Amidotetrahydropyrans via the Prins-Ritter Reaction Sequence.

ChemInform ◽  
2008 ◽  
Vol 39 (38) ◽  
Author(s):  
J. S. Yadav ◽  
B. V. Subba Reddy ◽  
S. Aravind ◽  
G. G. K. S. Narayana Kumar ◽  
C. Madhavi ◽  
...  
Keyword(s):  
Ritter Reaction ◽  
Diastereoselective Synthesis ◽  
Reaction Sequence ◽  
One Pot

Brook/Elimination/Aldol Reaction Sequence for the Direct One-Pot Preparation of Difluorinated Aldols from (Trifluoromethyl)trimethylsilane and Acylsilanes

2016 ◽  
Vol 358 (4) ◽  
pp. 526-531 ◽  
Author(s):  
Mélanie Decostanzi ◽  
Jérémy Godemert ◽  
Sylvain Oudeyer ◽  
Vincent Levacher ◽  
Jean-Marc Campagne ◽  
...  
Keyword(s):  
Aldol Reaction ◽  
Reaction Sequence ◽  
One Pot

Formal Synthesis of Actinoranone Using a Racemization-Free One-Pot Semipinacol Rearrangement/Wittig Reaction

2018 ◽  
Author(s):  
Martina Menger ◽  
Mathias Christmann
Keyword(s):  
Natural Product ◽  
Wittig Reaction ◽  
Reaction Sequence ◽  
One Pot ◽  
Formal Synthesis ◽  
Linear Sequence ◽  
Semipinacol Rearrangement ◽  
Key Steps

Here, we report a formal synthesis of the marine cytotoxic meroterpenoid actinoranone. Key steps include a racemization-free semipinacol rearrangement/Wittig reaction sequence and a chiral pool approach for the syntheses of the tetralone and the decalin fragments, respectively. The presented route provides access to the natural product in 14 steps in the longest linear sequence.

In-Situ Synthesis of Active Pharmaceutical Ingredients Which Content Pyrazole Skeleton

2020 ◽  
Vol 17 (10) ◽  
pp. 743-748
Author(s):  
Sultan Pathan ◽  
Anil Repale ◽  
Girdhar Pal
Keyword(s):  
Aldol Condensation ◽  
Active Pharmaceutical Ingredients ◽  
Reaction Sequence ◽  
One Pot ◽  
Pharmaceutical Ingredients ◽  
One Pot Synthesis ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Work Up

Celecoxib containing pyrazole derivatives were synthesized by path aldol condensation of substituted ketone with trifluoroethyl acetate subsequently by cyclization of the formed chalcones with 4-methanesulfonylphenylhydrazine. Here, a one-pot synthesis of celecoxib and substituted analogues have been reported which are nonsteroidal anti-inflammatory drugs for their cyclooxygenase (COX) inhibition, anti-inflammatory activity and ulcerogenic liability. In order to intermediate work-up, a continuous one-pot synthesis has been developed, performing the entire reaction sequence that results in a shorter time with good yield.

One-Pot Three-Step Synthesis of Naphtho[2,3-a]carbazole- 5,13-diones using a Tandem Radical Alkylation-Cyclization- Aromatization Reaction Sequence

2010 ◽  
Vol 352 (5) ◽  
pp. 847-853 ◽  
Author(s):  
Chunyong Ding ◽  
Shanghui Tu ◽  
Qizheng Yao ◽  
Fulong Li ◽  
Yuanxiang Wang ◽  
...  
Keyword(s):  
Reaction Sequence ◽  
One Pot ◽  
Aromatization Reaction
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