Uncatalyzed One-Pot Synthesis of Highly Substituted Pyridazines and Pyrazoline-Spirooxindoles via Domino SN/Condensation/Aza-ene Addition Cyclization Reaction Sequence

2013 ◽  
Vol 15 (6) ◽  
pp. 278-286 ◽  
Author(s):  
Nasrin Zohreh ◽  
Abdolali Alizadeh
Keyword(s):  
Cyclization Reaction ◽  
Reaction Sequence ◽  
One Pot ◽  
One Pot Synthesis ◽  
Ene Addition

One-Pot Synthesis of 1,2-Disubstituted 4-, 5-, 6-, and 7-Azaindoles from Amino-o-halopyridines via N-Arylation/Sonogashira/Cyclization Reaction

2017 ◽  
Vol 19 (19) ◽  
pp. 5118-5121 ◽  
Author(s):  
Sara I. Purificação ◽  
Marina J. D. Pires ◽  
Rafael Rippel ◽  
A. Sofia Santos ◽  
M. Manuel B. Marques
Keyword(s):  
Cyclization Reaction ◽  
One Pot ◽  
One Pot Synthesis

One-Pot Synthesis of Highly Substituted Allenylidene Derivatives via Palladium- or Nickel-Catalyzed Tandem Michael Addition-Cyclization Reaction

2009 ◽  
Vol 351 (1-2) ◽  
pp. 141-146 ◽  
Author(s):  
Yun Shi ◽  
Jing Huang ◽  
Yan-Fang Yang ◽  
Lu-Yong Wu ◽  
Yan-Ning Niu ◽  
...  
Keyword(s):  
Michael Addition ◽  
Cyclization Reaction ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals A Synthesis of 4-Chloro-2-(trichloromethyl)pyrimidines and Their Study in Nucleophilic Substitution

Synthesis ◽  
2018 ◽  
Vol 51 (02) ◽  
pp. 530-537 ◽  
Author(s):  
Moisés Romero-Ortega ◽  
Michelle Trujillo-Lagunas ◽  
Ignacio Medina-Mercado ◽  
Ivann Zaragoza-Galicia ◽  
Horacio Olivo
Keyword(s):  
Nucleophilic Substitution ◽  
Intramolecular Cyclization ◽  
Nitrogen Heterocycles ◽  
Cyclization Reaction ◽  
Substitution Reactions ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Acyl Chlorides ◽  
Nucleophilic Substitution Reactions ◽  
One Pot Synthesis

A convenient two-step, one-pot synthesis of 4-chloro-2-(trichloromethyl)pyrimidines starting from 2-(trichloromethyl)-1,3-diazabutadienes is described. These nitrogen heterocycles were prepared by a sequential acylation/intramolecular cyclization reaction between 2-(trichloromethyl)-1,3-diazabutadienes and acyl chlorides in the presence of triethylamine followed by treatment with POCl3. This is the first report for the synthesis of this type of 4-chloro-2-(trichloromethyl)pyrimidine derivatives and serves as a source for a wide variety of other substituted pyrimidines by nucleophilic substitution reactions.

Diverse privileged N-polycyclic skeletons accessed from a metal-free cascade cyclization reaction

2021 ◽  
Vol 19 (37) ◽  
pp. 8086-8095
Author(s):  
Wenzhong Li ◽  
Yu Wang ◽  
Huijing Qi ◽  
Ran Shi ◽  
Jiazhu Li ◽  
...  
Keyword(s):  
Membered Ring ◽  
Cyclization Reaction ◽  
One Pot ◽  
Metal Free ◽  
Cascade Cyclization ◽  
One Pot Synthesis ◽  
Ring Compounds

Metal-free cascade cyclization of 2-acylbenzoic acids with amines provided a one-pot synthesis of diverse isoindoloisoquinoline and benzoindolizinoindole derivatives, which were subsequently used to produce nitrogen-containing nine-membered ring compounds.

One‐pot synthesis of 3‐(sulfonyl)‐5,6,7,8‐tetrahydro‐4H‐pyrano[3,2‐c]pyridines through a cascade Michael/cyclization reaction

2019 ◽  
Vol 67 (5) ◽  
pp. 821-828
Author(s):  
Dao‐Cai Wang ◽  
Fei Ma ◽  
Qiang Xiao ◽  
Chi Zhang ◽  
Mian Huang ◽  
...  
Keyword(s):  
Cyclization Reaction ◽  
One Pot ◽  
One Pot Synthesis

Sequential Pd(0)/Fe(III) Catalyzed Azide–Isocyanide Coupling/Cyclization Reaction: One-Pot Synthesis of Aminotetrazoles

2018 ◽  
Vol 83 (16) ◽  
pp. 9530-9537 ◽  
Author(s):  
Ramdas S. Pathare ◽  
Arshad J. Ansari ◽  
Sarika Verma ◽  
Anand Maurya ◽  
Antim K. Maurya ◽  
...  
Keyword(s):  
Cyclization Reaction ◽  
One Pot ◽  
One Pot Synthesis

ChemInform Abstract: One-Pot Synthesis of Pyrrolo[3,2,1-kl]phenothiazines Through Copper-Catalyzed Tandem Coupling/Double Cyclization Reaction.

ChemInform ◽  
2016 ◽  
Vol 47 (11) ◽  
pp. no-no
Author(s):  
Jiaming Tang ◽  
Bingqing Xu ◽  
Xi Mao ◽  
Hongyan Yang ◽  
Xiaoxia Wang ◽  
...  
Keyword(s):  
Cyclization Reaction ◽  
One Pot ◽  
One Pot Synthesis
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