Carbene Complexes of Phosphorus(V) Fluorides by Oxidative Addition of 2,2-Difluorobis(dialkylamines) to Phosphorus(III) Halides

2011 ◽  
Vol 31 (4) ◽  
pp. 1278-1280 ◽  
Author(s):  
Tobias Böttcher ◽  
Oleg Shyshkov ◽  
Matthias Bremer ◽  
Bassem S. Bassil ◽  
Gerd-Volker Röschenthaler
Keyword(s):  
Oxidative Addition ◽  
Carbene Complexes

scholarly journals Reactivity of cationic gold(I) carbene complexes toward oxidative addition of bromine

2012 ◽  
Vol 391 ◽  
pp. 141-149 ◽  
Author(s):  
Luciano Canovese ◽  
Fabiano Visentin ◽  
Carlo Levi ◽  
Claudio Santo
Keyword(s):  
Oxidative Addition ◽  
Carbene Complexes ◽  
Cationic Gold

Carbene complexes of phosphorus(v) fluorides substituted with perfluoroalkyl-groups synthesized by oxidative addition. Cleavage of the complexes reveals a new synthetic protocol for ionic liquids

2014 ◽  
Vol 43 (7) ◽  
pp. 2979-2987 ◽  
Author(s):  
Tobias Böttcher ◽  
Simon Steinhauer ◽  
Nadine Allefeld ◽  
Berthold Hoge ◽  
Beate Neumann ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Oxidative Addition ◽  
Carbene Complexes

Facile Oxidative Addition of Organic Halides to Heteroleptic and Homoleptic Pd0-N-Heterocyclic Carbene Complexes

2011 ◽  
Vol 2011 (11) ◽  
pp. 1750-1761 ◽  
Author(s):  
Jung-Hyun Lee ◽  
Hyeong-Tak Jeon ◽  
Yong-Joo Kim ◽  
Kyung-Eun Lee ◽  
Young Ok Jang ◽  
...  
Keyword(s):  
Oxidative Addition ◽  
Carbene Complexes ◽  
Organic Halides

Bis-carbene complexes from oxidative addition of imidazolium C–H bonds to palladium(0)

2002 ◽  
pp. 2163-2167 ◽  
Author(s):  
Stephan Gründemann ◽  
Martin Albrecht ◽  
Anes Kovacevic ◽  
Jack W. Faller ◽  
Robert H. Crabtree
Keyword(s):  
Oxidative Addition ◽  
Carbene Complexes

Nickel(II) Pincer Carbene Complexes: Oxidative Addition of an Aryl C–H Bond to Form a Ni(II) Hydride

2014 ◽  
Vol 34 (2) ◽  
pp. 399-407 ◽  
Author(s):  
Ellen M. Matson ◽  
Gabriel Espinosa Martinez ◽  
Abdulrahman D. Ibrahim ◽  
Bailey J. Jackson ◽  
Jeffrey A. Bertke ◽  
...  
Keyword(s):  
Oxidative Addition ◽  
Carbene Complexes

scholarly journals Synthesis of Platinum(II) N-Heterocyclic Carbenes Based on Adenosine

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5384
Author(s):  
Maria Inês P. S. Leitão ◽  
Giulia Francescato ◽  
Clara S. B. Gomes ◽  
Ana Petronilho
Keyword(s):  
Methyl Iodide ◽  
Oxidative Addition ◽  
Heterocyclic Carbenes ◽  
Carbene Complexes ◽  
Promising Strategy ◽  
Ribose Moiety ◽  
Therapeutic Profile

Organometallic derivatization of nucleosides is a highly promising strategy for the improvement of the therapeutic profile of nucleosides. Herein, a methodology for the synthesis of metalated adenosine with a deprotected ribose moiety is described. Platinum(II) N-heterocyclic carbene complexes based on adenosine were synthesized, namely N-heterocyclic carbenes bearing a protected and unprotected ribose ring. Reaction of the 8-bromo-2′,3′,5′-tri-O-acetyladenosine with Pt(PPh3)4 by C8−Br oxidative addition yielded complex 1, with a PtII centre bonded to C-8 and an unprotonated N7. Complex 1 reacted at N7 with HBF4 or methyl iodide, yielding protic carbene 2 or methyl carbene 3, respectively. Deprotection of 1 to yield 4 was achieved with NH4OH. Deprotected compound 4 reacted at N7 with HCl solutions to yield protic NHC 5 or with methyl iodide yielding methyl carbene 6. Protic N-heterocyclic carbene 5 is not stable in DMSO solutions leading to the formation of compound 7, in which a bromide was replaced by chloride. The cis-influence of complexes 1–7 was examined by 31P{1H} and 195Pt NMR. Complexes 2, 3, 5, 6 and 7 induce a decrease of 1JPt,P of more than 300 Hz, as result of the higher cis-influence of the N-heterocyclic carbene when compared to the azolato ligand in 1 and 4.

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