Varioxepine A, a 3H-Oxepine-Containing Alkaloid with a New Oxa-Cage from the Marine Algal-Derived Endophytic Fungus Paecilomyces variotii

2014 ◽  
Vol 16 (18) ◽  
pp. 4834-4837 ◽  
Author(s):  
Peng Zhang ◽  
Attila Mándi ◽  
Xiao-Ming Li ◽  
Feng-Yu Du ◽  
Jia-Ning Wang ◽  
...  
Keyword(s):  
Endophytic Fungus ◽  
Paecilomyces Variotii ◽  
Marine Algal

ChemInform Abstract: Varioxepine A, a 3H-Oxepine-Containing Alkaloid with a New Oxa-Cage from the Marine Algal-Derived Endophytic Fungus Paecilomyces variotii.

ChemInform ◽  
2015 ◽  
Vol 46 (13) ◽  
pp. no-no
Author(s):  
Peng Zhang ◽  
Attila Mandi ◽  
Xiao-Ming Li ◽  
Feng-Yu Du ◽  
Jia-Ning Wang ◽  
...  
Keyword(s):  
Endophytic Fungus ◽  
Paecilomyces Variotii ◽  
Marine Algal

scholarly journals Paecilomyces variotii as A Plant-Growth Promoter in Horticulture

Agronomy ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 597
Author(s):  
Alejandro Moreno-Gavíra ◽  
Fernando Diánez ◽  
Brenda Sánchez-Montesinos ◽  
Mila Santos
Keyword(s):  
Endophytic Fungus ◽  
Growth Promotion ◽  
Growth Parameters ◽  
Germination Percentage ◽  
Growth Promoter ◽  
Paecilomyces Variotii ◽  
Horticultural Crops ◽  
Natural Park ◽  
Root And Shoot Length ◽  
Positive Results

In the present study, P. variotii, an endophytic fungus isolated from plant roots from the Cabo de Gata Natural Park (Parque Nacional Cabo de Gata—Spain), was tested to determine the effect on the growth promotion of tomato and pepper seeds and seedlings. For these purposes, germination trials in a laboratory and two experiments in a commercial nursery and greenhouse conditions were performed. The P. variotii isolate has shown a high ability to produce siderophores and IAA, but low ability to solubilize P. High values for germination percentage, seedling vigor, root and shoot length were obtained by P. variotii on tomato and pepper against control. P. variotii applications resulted in improved most of the growth parameters evaluated, for both horticultural crops, with the best results in the development of pepper seedlings. The application of a higher dose of P. variotii improved most of the morphological parameters and the Dickson quality index (DQI) value in tomato in seedlings and plants. The establishment of the endophytic fungus at the root enabled its biostimulant effects to persist after transplantation without any additional application. Few studies have analyzed this species as a biostimulant. The positive results from the tests showed its high potential. The application of this isolate can be of enormous benefit to horticultural crops for its high reproductive and establishment capacity.

ChemInform Abstract: Oxepine-Containing Diketopiperazine Alkaloids from the Algal-Derived Endophytic Fungus Paecilomyces variotii EN-291

ChemInform ◽  
2015 ◽  
Vol 46 (44) ◽  
pp. no-no
Author(s):  
Peng Zhang ◽  
Xiao-Ming Li ◽  
Jia-Ning Wang ◽  
Bin-Gui Wang
Keyword(s):  
Endophytic Fungus ◽  
Paecilomyces Variotii

scholarly journals Varioloid A, a new indolyl-6,10b-dihydro-5aH-[1]benzofuro[2,3-b]indole derivative from the marine alga-derived endophytic fungus Paecilomyces variotii EN-291

2016 ◽  
Vol 12 ◽  
pp. 2012-2018 ◽  
Author(s):  
Peng Zhang ◽  
Xiao-Ming Li ◽  
Xin-Xin Mao ◽  
Attila Mándi ◽  
Tibor Kurtán ◽  
...  
Keyword(s):  
Endophytic Fungus ◽  
Density Functional ◽  
Indole Derivative ◽  
Marine Alga ◽  
2D Nmr ◽  
Paecilomyces Variotii ◽  
Functional Theory ◽  
Nmr Data ◽  
Hepg2 Cell Lines ◽  
C Nmr

A new indolyl-6,10b-dihydro-5aH-[1]benzofuro[2,3-b]indole derivative, varioloid A (1), was isolated from the marine alga-derived endophytic fungus Paecilomyces variotii EN-291. Its structure was elucidated on the basis of extensive analysis of 1D and 2D NMR data and the absolute configuration was determined by time-dependent density functional theory-electronic circular dichroism (TDDFT-ECD) calculations. A similar compound, whose planar structure was previously described but the relative and absolute configurations and 13C NMR data were not reported, was also identified and was tentatively named as varioloid B (2). Both compounds 1 and 2 exhibited cytotoxicity against A549, HCT116, and HepG2 cell lines, with IC50 values ranging from 2.6 to 8.2 µg/mL.

scholarly journals Prenylated Diphenyl Ethers from the Marine Algal-Derived Endophytic Fungus Aspergillus tennesseensis

Molecules ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 2368 ◽  
Author(s):  
Zhao-Xia Li ◽  
Xiu-Fang Wang ◽  
Guang-Wei Ren ◽  
Xiao-Long Yuan ◽  
Ning Deng ◽  
...  
Keyword(s):  
Endophytic Fungus ◽  
Diphenyl Ether ◽  
Antimicrobial Activities ◽  
Cytotoxic Activities ◽  
Ic50 Value ◽  
Diphenyl Ethers ◽  
Marine Algal ◽  
Spectroscopy Studies ◽  
New Compounds

Considerable attention has been paid to marine derived endophytic fungi, owing to their capacity to produce novel secondary metabolites with potent bioactivities. In this study, two new compounds with a prenylated diphenyl ether structure—diorcinol L (1) and (R)-diorcinol B (2)—were isolated from the marine algal-derived endophytic fungus Aspergillus tennesseensis, along with seven known compounds: (S)-diorcinol B (3), 9-acetyldiorcinol B (4), diorcinol C (5), diorcinol D (6), diorcinol E (7), diorcinol J (8), and a dihydrobenzofuran derivative 9. Their structures were elucidated by extensive NMR spectroscopy studies. Compound 2 represents the first example of an R-configuration in the prenylated moiety. All these isolated compounds were examined for antimicrobial and cytotoxic activities. Compounds 1–9 exhibited antimicrobial activities against some human- and plant-pathogenic microbes with MIC values ranging from 2 to 64 μg/mL. Moreover, compound 9 displayed considerable inhibitory activity against the THP-1 cell line in vitro, with an IC50 value of 7.0 μg/mL.

scholarly journals Antimicrobial Meroterpenoids and Erythritol Derivatives Isolated from the Marine-Algal-Derived Endophytic Fungus Penicillium chrysogenum XNM-12

Marine Drugs ◽  
2020 ◽  
Vol 18 (11) ◽  
pp. 578
Author(s):  
Kuo Xu ◽  
Xu-Lun Wei ◽  
Lin Xue ◽  
Zhong-Feng Zhang ◽  
Peng Zhang
Keyword(s):  
Plant Pathogen ◽  
Endophytic Fungus ◽  
Penicillium Chrysogenum ◽  
2D Nmr ◽  
Antimicrobial Activities ◽  
Penicillium Species ◽  
Pyrone Ring ◽  
Planar Structures ◽  
Marine Algal ◽  
Optical Rotations

One new meroterpenoid-type alkaloid, oxalicine C (1), and two new erythritol derivatives, penicierythritols A (6) and B (7), together with four known meroterpenoids (2–5), were isolated from the marine algal-derived endophytic fungus Penicillium chrysogenum XNM-12. Their planar structures were determined by means of spectroscopic analyses, including UV, 1D and 2D NMR, and HRESIMS spectra. Their stereochemical configurations were established by comparing the experimental and calculated electronic circular dichroism (ECD) spectra for compound 1, as well as by comparison of the optical rotations with literature data for compounds 6 and 7. Notably, oxalicine C (1) represents the first example of an oxalicine alkaloid with a cleaved α-pyrone ring, whereas penicierythritols A (6) and B (7) are the first reported from the Penicillium species. The antimicrobial activities of compounds 1–7 were evaluated. Compounds 1 and 6 exhibited moderate antibacterial effects against the plant pathogen Ralstonia solanacearum with minimum inhibitory concentration (MIC) values of 8 and 4 μg/mL, respectively. Compound 6 also possesses moderate antifungal properties against the plant pathogen Alternaria alternata with a MIC value of 8 μg/mL.

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