C-Terminal Acetylene Derivatized Peptides via Silyl-Based Alkyne Immobilization

2013 ◽  
Vol 15 (12) ◽  
pp. 3126-3129 ◽  
Author(s):  
Martin Strack ◽  
Nils Metzler-Nolte ◽  
H. Bauke Albada
Keyword(s):  
Terminal Acetylene

Manganese-Catalyzed Benzene Synthesis by [2+2+2] Coupling of 1,3-Dicarbonyl Compound and Terminal Acetylene

2008 ◽  
Vol 130 (25) ◽  
pp. 7792-7793 ◽  
Author(s):  
Hayato Tsuji ◽  
Ken-ichi Yamagata ◽  
Taisuke Fujimoto ◽  
Eiichi Nakamura
Keyword(s):  
Terminal Acetylene ◽  
Dicarbonyl Compound

An approach to the synthesis of bruceantin. The synthesis of a tetracyclic intermediate

1989 ◽  
Vol 67 (12) ◽  
pp. 2237-2240 ◽  
Author(s):  
Sultan Darvesh ◽  
Andrew S. Grant ◽  
David I. Magee ◽  
Zdenek Valenta
Keyword(s):  
Sigmatropic Rearrangement ◽  
Terminal Acetylene ◽  
Chiral Centers ◽  
Oxygen Functionality

An intermediate (20) containing four of the five rings and seven of the ten chiral centers of bruceantin (1) was prepared. In a key reaction, 3-iodo-1-trimethylsilyl-5-hexen-1-yne (9) was found to add chemoselectively and stereoselectively to a dianion. The sequence also includes a selective attack by a sulfinate (17) on the terminal acetylene C-atom of the dianion of a keto acetylene, a concomitant cyclization in which the acetylene acts as an electrophile, and the use of the resulting allyl sulfoxide for the introduction of oxygen functionality by a reductive rearrangement. Keywords: bruceantin, sigmatropic rearrangement, stereoselective alkylation.

Occurrence of a 1,2 shift during enzymic and chemical oxidation of a terminal acetylene

1980 ◽  
Vol 102 (24) ◽  
pp. 7373-7375 ◽  
Author(s):  
Paul R. Ortiz de Montellano ◽  
Kent L. Kunze
Keyword(s):  
Chemical Oxidation ◽  
Terminal Acetylene

Mechanism-Based Inactivation of Cytochrome P450 2B6 by a Novel Terminal Acetylene Inhibitor

2003 ◽  
Vol 31 (1) ◽  
pp. 28-36 ◽  
Author(s):  
Peter W. Fan ◽  
Chungang Gu ◽  
Sandra A. Marsh ◽  
Jeffrey C. Stevens
Keyword(s):  
Cytochrome P450 ◽  
Terminal Acetylene ◽  
Cytochrome P450 2B6

scholarly journals Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks

2016 ◽  
Vol 19 (1) ◽  
pp. 142-145 ◽  
Author(s):  
Narendran G-Dayanandan ◽  
Eric W. Scocchera ◽  
Santosh Keshipeddy ◽  
Heather F. Jones ◽  
Amy C. Anderson ◽  
...  
Keyword(s):  
Building Blocks ◽  
Terminal Acetylene ◽  
Direct Substitution

scholarly journals Polymerization of Phenylacetylene-Based Monodendrons with Alkoxy Peripheral Groups and Oxygen/Nitrogen Permeation Behavior of Their Membranes

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Takashi Kaneko ◽  
Kazuaki Sato ◽  
Yoshihiko Uchiya ◽  
Masahiro Teraguchi ◽  
Toshiki Aoki
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Organic Solvents ◽  
Focal Point ◽  
Rhodium Catalyst ◽  
Terminal Acetylene ◽  
Permselective Membrane

Monodendron monomers with alkoxy peripheral groups were synthesized, and the focal point of monodendrons, terminal acetylene, was polymerized with rhodium catalyst to yield corresponding polydendrons with a high molecular weight. The polydendrons were soluble in common organic solvents and readily formed membranes. Oxygen permselectivity was improved in the polydendrons with a space-persistent dendritic crowd. It was found that the well-defined dendritic and rod-like structure of the polydendrons was useful for permselective membrane.

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