Asymmetric Hydroformylation of Vinyl Acetate:  Application in the Synthesis of Optically Active Isoxazolines and Imidazoles

2007 ◽  
Vol 9 (14) ◽  
pp. 2665-2668 ◽  
Author(s):  
P. J. Thomas ◽  
Alex T. Axtell ◽  
Jerzy Klosin ◽  
Wei Peng ◽  
Cynthia L. Rand ◽  
...  
Keyword(s):  
Vinyl Acetate ◽  
Optically Active ◽  
Asymmetric Hydroformylation

scholarly journals Chemoenzymatic synthesis and biological evaluation of enantiomerically enriched 1-(β-hydroxypropyl)imidazolium- and triazolium-based ionic liquids

2013 ◽  
Vol 9 ◽  
pp. 516-525 ◽  
Author(s):  
Paweł Borowiecki ◽  
Małgorzata Milner-Krawczyk ◽  
Jan Plenkiewicz
Keyword(s):  
Ionic Liquids ◽  
Vinyl Acetate ◽  
Propylene Oxide ◽  
Ring Opening ◽  
Biological Evaluation ◽  
Optically Active ◽  
Chemoenzymatic Synthesis ◽  
Alkyl Bromides ◽  
Wide Range ◽  
Synthesis And Biological Evaluation

Racemic 1-(β-hydroxypropyl)azoles were prepared by solvent-free direct regioselective ring opening of 1,2-propylene oxide with imidazole or 1,2,4-triazole. Lipase-catalyzed transesterification of alcohols with vinyl acetate resulted in kinetic enantiomers resolution. Separated (S)-enantiomers of (+)-1-(1H-imidazol-1-yl)propan-2-ol and (+)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol were quaternized with alkyl bromides or iodides, yielding novel optically active ionic liquids. Racemic salts were tested against a wide range of microorganisms.

Asymmetric hydroformylation of vinyl acetate by use of chiral bis(triarylphosphite)-rhodium(I) complexes

1992 ◽  
Vol 3 (5) ◽  
pp. 583-586 ◽  
Author(s):  
Nozomu Sakai ◽  
Kyoko Nozaki ◽  
Kazushi Mashima ◽  
Hidemasa Takaya
Keyword(s):  
Vinyl Acetate ◽  
Asymmetric Hydroformylation

Asymmetric hydroformylation of vinyl acetate with DIOP-type ligands

1981 ◽  
Vol 46 (22) ◽  
pp. 4422-4427 ◽  
Author(s):  
Charles F. Hobbs ◽  
W. S. Knowles
Keyword(s):  
Vinyl Acetate ◽  
Asymmetric Hydroformylation
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