Olefin Metathesis in the Design and Synthesis of a Globally Constrained Grb2 SH2 Domain Inhibitor

2001 ◽  
Vol 3 (11) ◽  
pp. 1617-1620 ◽  
Author(s):  
Yang Gao ◽  
Chang-Qing Wei ◽  
Terrence R. Burke
Keyword(s):  
Olefin Metathesis ◽  
Sh2 Domain ◽  
Design And Synthesis

ChemInform Abstract: Olefin Metathesis in the Design and Synthesis of a Globally Constrained Grb2 SH2 Domain Inhibitor.

ChemInform ◽  
2010 ◽  
Vol 32 (37) ◽  
pp. no-no
Author(s):  
Yang Gao ◽  
Chang-Qing Wei ◽  
Terrence R. Burke Jr.
Keyword(s):  
Olefin Metathesis ◽  
Sh2 Domain ◽  
Design And Synthesis

Application of Phenylphosphate Mimetics to the Design and Synthesis of Olefin Metathesis-Derived Grb2 SH2 Domain-Binding Macrocycles

2006 ◽  
pp. 180-181
Author(s):  
Sang-Uk Kang ◽  
Zhen-Dan Shi1 ◽  
Rajeshri Kariki1 ◽  
Jason Phan ◽  
Karen M. Worthy ◽  
...  
Keyword(s):  
Olefin Metathesis ◽  
Sh2 Domain ◽  
Design And Synthesis

Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 2

2000 ◽  
Vol 10 (20) ◽  
pp. 2343-2346 ◽  
Author(s):  
Clive V Walker ◽  
Giorgio Caravatti ◽  
Alastair A Denholm ◽  
John Egerton ◽  
Alex Faessler ◽  
...  
Keyword(s):  
Sh2 Domain ◽  
Design And Synthesis

Design and synthesis of constrained epothilone analogs: The efficient synthesis of eleven-membered rings by olefin metathesis

Tetrahedron ◽  
1999 ◽  
Vol 55 (27) ◽  
pp. 8199-8214 ◽  
Author(s):  
Jeffrey D. Winkler ◽  
Joanne M. Holland ◽  
Jiri Kasparec ◽  
Paul H. Axelsen
Keyword(s):  
Olefin Metathesis ◽  
Efficient Synthesis ◽  
Design And Synthesis

Design and synthesis of conformationally constrained, extended and reverse turn pseudopeptides as Grb2-SH2 domain antagonists

2003 ◽  
Vol 44 (8) ◽  
pp. 1571-1574 ◽  
Author(s):  
Hilary R Plake ◽  
Thomas B Sundberg ◽  
Angela R Woodward ◽  
Stephen F Martin
Keyword(s):  
Sh2 Domain ◽  
Conformationally Constrained ◽  
Design And Synthesis ◽  
Reverse Turn

Design and Synthesis of Non-peptidic Inhibitors for the Syk C-Terminal SH2 Domain Based on Structure-Based In-Silico Screening

2001 ◽  
Vol 44 (26) ◽  
pp. 4737-4740 ◽  
Author(s):  
Tatsuya Niimi ◽  
Masaya Orita ◽  
Miwa Okazawa-Igarashi ◽  
Hitoshi Sakashita ◽  
Kazumi Kikuchi ◽  
...  
Keyword(s):  
In Silico ◽  
Sh2 Domain ◽  
In Silico Screening ◽  
Design And Synthesis ◽  
Peptidic Inhibitors

scholarly journals Design and synthesis of a potential SH2 domain inhibitor bearing a stereodiversified 1,4-cis-enediol scaffold

Tetrahedron ◽  
2011 ◽  
Vol 67 (52) ◽  
pp. 10216-10221 ◽  
Author(s):  
Christine Marian ◽  
Rong Huang ◽  
Richard F. Borch
Keyword(s):  
Sh2 Domain ◽  
Design And Synthesis

Design and Synthesis of Photoresponsive Crown Ethers via Olefin Metathesis

Heterocycles ◽  
1988 ◽  
Vol 27 (10) ◽  
pp. 2293 ◽  
Author(s):  
Ken Kanematsu ◽  
Kenji Hayakawa ◽  
Ryo Naito
Keyword(s):  
Crown Ethers ◽  
Olefin Metathesis ◽  
Design And Synthesis

ChemInform Abstract: Design and Synthesis of Constrained Epothilone Analogues: The Efficient Synthesis of Eleven-Membered Rings by Olefin Metathesis.

ChemInform ◽  
2010 ◽  
Vol 30 (39) ◽  
pp. no-no
Author(s):  
Jeffrey D. Winkler ◽  
Joanne M. Holland ◽  
Jiri Kasparec ◽  
Paul H. Axelsen
Keyword(s):  
Olefin Metathesis ◽  
Efficient Synthesis ◽  
Design And Synthesis
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