Natural Compounds in Cancer Therapy:  Promising Nontoxic Antitumor Agents from Plants and Other Natural Sources John Boik (University of Texas). Oregon Medical Press, Princeton, MN. 2001. viii + 521 pp. 21.5 × 27.5 cm. $32.00. ISBN 0-9648280-1-4.

2001 ◽  
Vol 64 (12) ◽  
pp. 1605-1606 ◽  
Author(s):  
David J. Kroll
Keyword(s):  
Cancer Therapy ◽  
Antitumor Agents ◽  
Natural Compounds ◽  
Natural Sources ◽  
University Of Texas

scholarly journals Natural compounds as potential adjuvants to cancer therapy: Preclinical evidence

2019 ◽  
Vol 177 (6) ◽  
pp. 1409-1423 ◽  
Author(s):  
Shian‐Ren Lin ◽  
Chia‐Hsiang Chang ◽  
Che‐Fang Hsu ◽  
May‐Jwan Tsai ◽  
Henrich Cheng ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Natural Compounds

Coagulation and Cancer Therapy: The Potential of Natural Compounds

2005 ◽  
Vol 6 (6) ◽  
pp. 461-469 ◽  
Author(s):  
G. Justo ◽  
C. Ferreira
Keyword(s):  
Cancer Therapy ◽  
Natural Compounds

scholarly journals Natural Compounds from Herbs that can Potentially Execute as Autophagy Inducers for Cancer Therapy

2017 ◽  
Vol 18 (7) ◽  
pp. 1412 ◽  
Author(s):  
Shian-Ren Lin ◽  
Yaw-Syan Fu ◽  
May-Jywan Tsai ◽  
Henrich Cheng ◽  
Ching-Feng Weng
Keyword(s):  
Cancer Therapy ◽  
Natural Compounds

Dna Sequence Specificity of Antitumor Agents: Oncogenes as possible targets for cancer therapy

1988 ◽  
Vol 27 (5) ◽  
pp. 503-510 ◽  
Author(s):  
J. A. Hartley ◽  
J. W. Lown ◽  
W. B. Mattes ◽  
K. W. Kohn
Keyword(s):  
Cancer Therapy ◽  
Dna Sequence ◽  
Antitumor Agents ◽  
Sequence Specificity ◽  
Dna Sequence Specificity

scholarly journals Exosome-Based Delivery of Natural Products in Cancer Therapy

2021 ◽  
Vol 9 ◽  
Author(s):  
Hang Song ◽  
Bin Liu ◽  
Bin Dong ◽  
Jing Xu ◽  
Hui Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Natural Products ◽  
Cancer Therapy ◽  
Natural Product ◽  
Current Knowledge ◽  
Donor Cell ◽  
Natural Compounds ◽  
Cellular Behaviors ◽  
Delivery Vehicles ◽  
Intercellular Communications

A rapidly growing research evidence has begun to shed light on the potential application of exosome, which modulates intercellular communications. As donor cell released vesicles, exosomes could play roles as a regulator of cellular behaviors in up-taken cells, as well as a delivery carrier of drugs for targeted cells. Natural product is an invaluable drug resources and it is used widely as therapeutic agents in cancers. This review summarizes the most recent advances in exosomes as natural product delivery carriers in cancer therapy from the following aspects: composition of exosomes, biogenesis of exosomes, and its functions in cancers. The main focus is the advantages and applications of exosomes for drug delivery in cancer therapy. This review also summarizes the isolation and application of exosomes as delivery carriers of natural products in cancer therapy. The recent progress and challenges of using exosomes as drug delivery vehicles for five representative anti-cancer natural products including paclitaxel, curcumin, doxorubicin, celastrol, and β-Elemene. Based on the discussion on the current knowledge about exosomes as delivery vehicles for drugs and natural compounds to the targeted site, this review delineates the landscape of the recent research, challenges, trends and prospects in exosomes as delivery vehicles for drugs and natural compounds for cancer treatment.

scholarly journals Targeting Autophagy with Natural Compounds in Cancer: A Renewed Perspective from Molecular Mechanisms to Targeted Therapy

2021 ◽  
Vol 12 ◽  
Author(s):  
Qiang Xie ◽  
Yi Chen ◽  
Huidan Tan ◽  
Bo Liu ◽  
Ling-Li Zheng ◽  
...  
Keyword(s):  
Natural Products ◽  
Cancer Therapy ◽  
Signaling Pathways ◽  
Small Molecule ◽  
Molecular Mechanisms ◽  
Biological Activities ◽  
Natural Compounds ◽  
Therapeutic Effects ◽  
Therapeutic Benefits ◽  
Small Molecule Drugs

Natural products are well-characterized to have pharmacological or biological activities that can be of therapeutic benefits for cancer therapy, which also provide an important source of inspiration for discovery of potential novel small-molecule drugs. In the past three decades, accumulating evidence has revealed that natural products can modulate a series of key autophagic signaling pathways and display therapeutic effects in different types of human cancers. In this review, we focus on summarizing some representative natural active compounds, mainly including curcumin, resveratrol, paclitaxel, Bufalin, and Ursolic acid that may ultimately trigger cancer cell death through the regulation of some key autophagic signaling pathways, such as RAS-RAF-MEK-ERK, PI3K-AKT-mTOR, AMPK, ULK1, Beclin-1, Atg5 and p53. Taken together, these inspiring findings would shed light on exploiting more natural compounds as candidate small-molecule drugs, by targeting the crucial pathways of autophagy for the future cancer therapy.

scholarly journals NATURAL ANTIVIRALS FOR THE MANAGEMENT OF SARS-COVID-19: A REVIEW

2021 ◽  
Vol 12 (3) ◽  
pp. 113-117
Author(s):  
Vasavi M ◽  
Pujitha M ◽  
Raagini G ◽  
Ramaiah M ◽  
Ramalingeswara Rao K
Keyword(s):  
Side Effects ◽  
Natural Compounds ◽  
New Disease ◽  
Viral Pathogens ◽  
Health Crisis ◽  
Natural Sources ◽  
Significant Challenge ◽  
Wide Range ◽  
History Of ◽  
Antiviral Activities

Unlike previous outbreaks like SARS and MERS, caused by corona family viruses, COVID-19 became a much worse worldwide pandemic. SARS CoV-2, another coronavirus, causes it. Finding effective therapeutics against this global health crisis became a significant challenge for researchers. However, Allopathic medicine is effective to some extent with severe side effects, which cause concern. In this process, some researchers focused on natural compounds like plant-synthesized secondary metabolites (PSMs) for the treatment of COVID-19. Because these natural compounds like PSMs had a history of tackling a wide range of viral pathogens successfully without significant side effects. Many medicinal plants from different families have antiviral activities. This review intends to systematically evaluate the natural metabolites that could be used against this new disease looking at their natural sources, mechanism of action, and previous pharmacological usages. So, it can be a good initiation for the greater goal of finding effective natural therapeutics for the treatment of Covid-19 without any severe side effects.

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