scholarly journals Photoacoustic Imaging of Mesenchymal Stem Cells in Living Mice via Silica-Coated Gold Nanorods

ACS Nano ◽  
2012 ◽  
Vol 6 (7) ◽  
pp. 5920-5930 ◽  
Author(s):  
Jesse V. Jokerst ◽  
Mridhula Thangaraj ◽  
Paul J. Kempen ◽  
Robert Sinclair ◽  
Sanjiv S. Gambhir
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Gold Nanorods ◽  
Photoacoustic Imaging

Photothermal Release and Recovery of Mesenchymal Stem Cells from Substrates Functionalized with Gold Nanorods

2021 ◽  
Author(s):  
Yashaswini Vegi ◽  
Mirren Charnley ◽  
Stuart K Earl ◽  
Carmine Onofrillo ◽  
Blanca del Rosal ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Gold Nanorods

Labelling of human Wharton's jelly‐derived mesenchymal stem cells with gold nanorods by biomimicry method

2021 ◽  
Author(s):  
Farshid Qiyami Hour ◽  
Ronak Shabani ◽  
Behnaz Ashtrai ◽  
Alaa Moinzadeh ◽  
Mehdi Mehdizadeh
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Gold Nanorods ◽  
Wharton’S Jelly ◽  
Wharton's Jelly

scholarly journals Polymer-Peptide Modified Gold Nanorods to Improve Cell Conjugation and Cell labelling for Stem Cells Photoacoustic Imaging

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1196
Author(s):  
Dina Salah ◽  
Farahat S. Moghanm ◽  
Muhammad Arshad ◽  
Abdulaziz A. Alanazi ◽  
Salman latif ◽  
...  
Keyword(s):  
Stem Cells ◽  
Contrast Agent ◽  
Surface Plasmon ◽  
Cellular Uptake ◽  
Gold Nanorods ◽  
Cell Tracking ◽  
Photoacoustic Imaging ◽  
Optical Measurements ◽  
Peptide Sequence ◽  
Ammonium Bromide

The use of gold nanorods (GNRs) as a contrast agent in bioimaging and cell tracking has numerous advantages, primarily due to the unique optical properties of gold nanorods which allow for the use of infrared regions when imaging. Owing to their unique geometry, Au NRs exhibit surface plasmon modes in the near-infrared wavelength range, which is ideal for carrying out optical measurements in biological fluids and tissue. Gold nanorod functionalization is essential, since the Cetyltrimethyl ammonium bromide CTAB gold nanorods are toxic, and for further in vitro and in vivo experiments the nanorods should be functionalized to become optically stable and biocompatible. In the present study, gold nanorods with an longitudinal surface plasmon resonance (LSPR) position around 800 nm were synthesized in order to be used for photoacoustic imaging applications for stem cell tracking. The gold nanorods were functionalized using both thiolated poly (ethylene glycol) (PEG) to stabilize the gold nanorods surface and a CALNN–TAT peptide sequence. Both ligands were attached to the gold nanorods through an Au–sulfur bond. CALNN–TAT is known as a cell penetrating peptide which ensures endocytosis of the gold nanorods inside the mesenchymal stem cells of mice (MSCD1). Surface modifications of gold nanorods were achieved using optical spectroscopy (UV–VIS), electron microscopy (TEM), zeta-potential, and FTIR. Gold nanorods were incubated in MSCD1 in order to achieve a cellular uptake that was characterized by a transmission electron microscope (TEM). For photoacoustic imaging, Multi-Spectral Optoacoustic Tomography (MSOT) was used. The results demonstrated good cellular uptake for PEG–CALNN–TAT GNRs and the successful use of modified gold nanorods as both a contrast agent in photoacoustic imaging and as a novel tracking bioimaging technique.

scholarly journals Stable H3 peptide was delivered by gold nanorods to inhibit LSD1 activation and induce human mesenchymal stem cells differentiation

Oncotarget ◽  
2017 ◽  
Vol 8 (14) ◽  
pp. 23110-23119 ◽  
Author(s):  
Xin Meng ◽  
Jianping Li ◽  
Minjuan Zheng ◽  
Lei Zuo ◽  
Chao Sun ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Gold Nanorods ◽  
Human Mesenchymal Stem Cells

Ultrasound and photoacoustic imaging to monitor mesenchymal stem cells labeled with gold nanoparticles

2011 ◽  
Author(s):  
Seung Yun Nam ◽  
Laura M. Ricles ◽  
Konstantin Sokolov ◽  
Laura J. Suggs ◽  
Stanislav Y. Emelianov
Keyword(s):  
Stem Cells ◽  
Gold Nanoparticles ◽  
Mesenchymal Stem Cells ◽  
Photoacoustic Imaging

scholarly journals Indocyanine green labeling for optical and photoacoustic imaging of mesenchymal stem cells after in vivo transplantation

2019 ◽  
Vol 12 (5) ◽  
Author(s):  
Miriam Filippi ◽  
Francesca Garello ◽  
Chiara Pasquino ◽  
Francesca Arena ◽  
Pierangela Giustetto ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Indocyanine Green ◽  
Photoacoustic Imaging

Multifunctional nanoparticles for intracellular drug delivery and photoacoustic imaging of mesenchymal stem cells

2019 ◽  
Vol 9 (3) ◽  
pp. 652-666 ◽  
Author(s):  
Isaac M. Adjei ◽  
Hao Yang ◽  
Glendon Plumton ◽  
Lorena Maldonado-Camargo ◽  
Jon Dobson ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Photoacoustic Imaging ◽  
Multifunctional Nanoparticles ◽  
Intracellular Drug Delivery
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