scholarly journals 17β-Estradiol Eye Drops Protect the Retinal Ganglion Cell Layer and Preserve Visual Function in an in Vivo Model of Glaucoma

2013 ◽  
Vol 10 (8) ◽  
pp. 3253-3261 ◽  
Author(s):  
Katalin Prokai-Tatrai ◽  
Hua Xin ◽  
Vien Nguyen ◽  
Szabolcs Szarka ◽  
Balazs Blazics ◽  
...  
1998 ◽  
Vol 236 (12) ◽  
pp. 904-915 ◽  
Author(s):  
M.-M. Gellrich ◽  
Stephan Neumaier ◽  
Claudia Auw-Hädrich ◽  
Nils-Claudius Gellrich ◽  
Lutz Lothar Hansen

2001 ◽  
Vol 73 (1) ◽  
pp. 45-57 ◽  
Author(s):  
Pamela Moore ◽  
Amira El-sherbeny ◽  
Penny Roon ◽  
Patricia V Schoenlein ◽  
Vadivel Ganapathy ◽  
...  

2020 ◽  
Author(s):  
Elena Gofas-Salas ◽  
Yuhua Rui ◽  
Pedro Mecê ◽  
Min Zhang ◽  
Valerie C. Snyder ◽  
...  

AbstractRetinal ganglion cells (RGCs) are the primary output neurons of the retina. RGC dysfunction and death can cause irreversible vision loss in glaucoma and other ocular diseases. However, no methods exist to evaluate RGCs at the level of single cell in the living human eye in the clinic. Our aim is to implement a technique revealing the retinal ganglion cell layer neurons whose contrast, robustness and acquisition time would make it suitable for clinical diagnosis and monitoring of patients. While previously we were able to demonstrate high contrast imaging in monkeys, here we propose a new adaptive optics scanning laser ophthalmoscope configuration that allows us to achieve similar results on humans in vivo. In particular we used a new detection scheme that allowed us to switch from two light sources to one thereby enabling us to increase the light power, eliminate problems caused by chromatic aberration and improve the image registration process. Here we show that this optimized detection scheme and image processing pipeline improve the multi-offset technique for imaging of human RGC layer neurons.


2015 ◽  
Vol 56 (10) ◽  
pp. 6095 ◽  
Author(s):  
Francisco M. Nadal-Nicolás ◽  
Paloma Sobrado-Calvo ◽  
Manuel Jiménez-López ◽  
Manuel Vidal-Sanz ◽  
Marta Agudo-Barriuso

2019 ◽  
Vol 19 (10) ◽  
pp. 41c
Author(s):  
Kara N Cloud ◽  
Min Chen ◽  
Jessica I. W. Morgan ◽  
Geoffrey K. Aguirre

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