Self-Association of the Thermosensitive Block Copolymer Poly(2-isopropyl-2-oxazoline)-b-poly(N-isopropylacrylamide) in Water–Methanol Mixtures

2014 ◽  
Vol 47 (19) ◽  
pp. 6900-6910 ◽  
Author(s):  
Rintaro Takahashi ◽  
Xing-Ping Qiu ◽  
Na Xue ◽  
Takahiro Sato ◽  
Ken Terao ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Self Association ◽  
Copolymer Poly

Self-Association of a Thermosensitive Amphiphilic Block Copolymer Poly(N-isopropylacrylamide)-b-poly(N-vinyl-2-pyrrolidone) in Aqueous Solution upon Heating

2012 ◽  
Vol 46 (1) ◽  
pp. 226-235 ◽  
Author(s):  
Takahiro Sato ◽  
Kohei Tanaka ◽  
Akiko Toyokura ◽  
Rika Mori ◽  
Rintaro Takahashi ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Block Copolymer ◽  
Amphiphilic Block Copolymer ◽  
Self Association ◽  
Copolymer Poly

Modular polymerized ionic liquid block copolymer membranes for CO2/N2 separation

2014 ◽  
Vol 2 (21) ◽  
pp. 7967-7972 ◽  
Author(s):  
Brian J. Adzima ◽  
Surendar R. Venna ◽  
Steven S. Klara ◽  
Hongkun He ◽  
Mingjiang Zhong ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Block Copolymer ◽  
Polymerized Ionic Liquid ◽  
Copolymer Poly ◽  
Poly Ionic Liquid

A robust and orthogonal approach to access modular block-copolymer poly(ionic liquid)s.

Polylactic acid block copolymer grafted temozolomide targeted nano delivery in the treatment of glioma

2021 ◽  
Vol 11 (5) ◽  
pp. 627-633
Author(s):  
Maokai Wang ◽  
Rongyan Kuang ◽  
Baoqing Huang ◽  
Defeng Ji
Keyword(s):  
Central Nervous System ◽  
Block Copolymer ◽  
Tumor Recurrence ◽  
Poly Lactic Acid ◽  
First Line ◽  
Kunitz Domain ◽  
The Central Nervous System ◽  
Modified Block ◽  
Copolymer Poly ◽  
Line Chemotherapy

Gliomas are tumors of the central nervous system; they can be invasive and are commonly treated by surgical resection, chemo, and radiotherapy. Removal of a glioma is dangerous and not always successful. Temozolomide (TMZ), the first-line chemotherapy drug for gliomas, inhibit tumor recurrence, and metastasis to some extent. TMZ is often accompanied by side effects such as anemia, fever, constipation, and more. Here using a double-targeted Kunitz domain Angiopep-2 (ANG) modified block copolymer poly(lactic acid)-polyethylene glycol (PEG-PLA) coated with TMZ, we constructed a nano-delivery system (ANG@PLA-PEG/TMZ) that crosses the blood-brain barrier (BBB) to treat gliomas.

Micellization of three-block copolymer poly[styrene-b-(ethene-co-butene)-b-styrene] in mixed solvents of tetrahydrofuran/ethanol

Polymer ◽  
1984 ◽  
Vol 25 (8) ◽  
pp. 1178-1184 ◽  
Author(s):  
B. Bednář ◽  
J. Devátý ◽  
B. Koupalová ◽  
J. Králiček ◽  
Z. Tuzar
Keyword(s):  
Block Copolymer ◽  
Mixed Solvents ◽  
Copolymer Poly

Photo- and Thermo-Dual-Responsive Organic/Inorganic Hybrid Materials

2013 ◽  
Vol 538 ◽  
pp. 181-184 ◽  
Author(s):  
Xin De Tang ◽  
Ye Chen ◽  
Fa Qi Yu ◽  
Mei Shan Pei
Keyword(s):  
Block Copolymer ◽  
Hybrid Materials ◽  
Self Assembly ◽  
Polymeric Materials ◽  
Stimuli Responsive ◽  
Inorganic Hybrid ◽  
Dual Responsive ◽  
Hexyl Methacrylate ◽  
Poly Ethylene ◽  
Copolymer Poly

Organic/inorganic hybrid materials based upon stimuli-responsive copolymers have attracted an inceasing attention. Compared with the polymeric materials, these hybrid materials can form aggregates in aqueous solution with much more stable shape-persistance due to the inorganic structure, which facilitate the mass delivery and long-term life. A novel hybrid material based on a new reactive block copolymer, poly(ethylene oxide)-block-poly{3-(trimethoxysilyl)propyl methacrylate-co-N-isopropylacrylamide-co-6-[4-(4-methoxyphenylazo)phenoxy]hexyl methacrylate} [PEO-P(TMSPMA-NIPAM-AzoMA)] was synthesized via atom transfer radical polymerization (ATRP). The vesicles were obtained by self-assembly of the resulting block copolymer in a selective solvent, and then the PTMSPMA block was subjected to hydrolysis and polycondensation reaction to fix vesicle wall in the presence of triethylamine as a catalyst. The photo- and thermo- dual-responsive properties of the vesicles were investigated.

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