Synthesis and solvent-dependent micellization of the amphiphilic block copolymer poly(styreneboronic acid)-block-polystyrene

2010 ◽  
Vol 48 (11) ◽  
pp. 2438-2445 ◽  
Author(s):  
Chengzhong Cui ◽  
Edward M. Bonder ◽  
Yang Qin ◽  
Frieder Jäkle
Keyword(s):  
Block Copolymer ◽  
Amphiphilic Block Copolymer ◽  
Copolymer Poly

Amphiphilic block copolymer poly(lactic acid)-block -(glycidylazide polymer)-block -polystyrene: synthesis and self-assembly

2017 ◽  
Vol 66 (7) ◽  
pp. 1037-1043 ◽  
Author(s):  
Guoping Li ◽  
Haoxue Dong ◽  
Menghui Liu ◽  
Min Xia ◽  
Chunpeng Chai ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Block Copolymer ◽  
Self Assembly ◽  
Amphiphilic Block Copolymer ◽  
Poly Lactic Acid ◽  
Copolymer Poly ◽  
Polymer Block

Amphiphilic block copolymer/poly(dimethylsiloxane) (PDMS) blends and nanocomposites for improved fouling-release

Biofouling ◽  
2011 ◽  
Vol 27 (5) ◽  
pp. 529-541 ◽  
Author(s):  
Elisa Martinelli ◽  
Marianna Suffredini ◽  
Giancarlo Galli ◽  
Antonella Glisenti ◽  
Michala E. Pettitt ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Amphiphilic Block Copolymer ◽  
Fouling Release ◽  
Copolymer Poly

Self-Association of a Thermosensitive Amphiphilic Block Copolymer Poly(N-isopropylacrylamide)-b-poly(N-vinyl-2-pyrrolidone) in Aqueous Solution upon Heating

2012 ◽  
Vol 46 (1) ◽  
pp. 226-235 ◽  
Author(s):  
Takahiro Sato ◽  
Kohei Tanaka ◽  
Akiko Toyokura ◽  
Rika Mori ◽  
Rintaro Takahashi ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Block Copolymer ◽  
Amphiphilic Block Copolymer ◽  
Self Association ◽  
Copolymer Poly

scholarly journals Amphiphilic Block Copolymer Poly (Acrylic Acid)-B-Polycaprolactone as a Novel pH-sensitive Nanocarrier for Anti-Cancer Drugs Delivery: In-vitro and In-vivo Evaluation

Polymers ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 820 ◽  
Author(s):  
Huanhuan Liu ◽  
Hong Chen ◽  
Fuhu Cao ◽  
Daiyin Peng ◽  
Weidong Chen ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Acrylic Acid ◽  
Polymeric Micelles ◽  
Drug Loading ◽  
Amphiphilic Block Copolymer ◽  
In Vivo Evaluation ◽  
Time Curve ◽  
Copolymer Poly ◽  
Poly Acrylic Acid

Gambogenic acid (GNA) has been demonstrated with outstanding antitumor activity as a potential antitumor drug in recent years. However, the low solubility and deficient bioavailability of GNA seriously hinder its practical application in the clinic area. In this study, a novel amphiphilic block copolymer, poly (acrylic acid)-b-polycaprolactone (PAA-b-PCL) is prepared and assembled into pH-responsive polymeric micelles (PMs) as one mold of drug delivery system (DDS) with unique properties. Relevant investigation on PMs exhibits excellent carrying potential and pH-dependent release performance for GNA. The drug loading capacity (DLC) and drug loading efficiency (DLE) for GNA-loaded PMs can be achieved as high as 15.20 ± 0.07% and 83.67 ± 0.49%, respectively. The in vitro experiments indicate that the GNA releasing time, cytotoxicity, and cellular uptake are significantly enhanced. Especially, the peak concentration (Cmax) and area under the curve (AUC) are promoted sharply in the GNA-loaded PMs concentration-time curve. This study not only provides a novel way to widen the application of anticancer GNA in the future, but also extends the potential of stimuli-responsive copolymers to biomedical applications.

scholarly journals Thiol-reactive amphiphilic block copolymer for coating gold nanoparticles with neutral and functionable surfaces

2014 ◽  
Vol 5 (8) ◽  
pp. 2768-2773 ◽  
Author(s):  
Hongwei Chen ◽  
Hao Zou ◽  
Hayley J. Paholak ◽  
Masayuki Ito ◽  
Wei Qian ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Block Copolymer ◽  
Ethylene Oxide ◽  
Amphiphilic Block Copolymer ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Copolymer Poly

We report a thiol-reactive amphiphilic block copolymer poly(ethylene oxide)-block-poly(pyridyldisulfide ethylmethacrylate) (PEO-b-PPDSM) for coating AuNPs. These individually dispersed AuNPs have unique surfaces that are both neutral and facile to functionalize.

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