scholarly journals Topological constraints and their influence on the properties of synthetic macromolecular systems. 2. Micelle formation of triblock copolymers

1987 ◽  
Vol 20 (3) ◽  
pp. 486-489 ◽  
Author(s):  
G. Ten Brinke ◽  
G. Hadziioannou
Keyword(s):  
Triblock Copolymers ◽  
Micelle Formation ◽  
Topological Constraints ◽  
Macromolecular Systems

SANS Investigations of Topological Constraints in Networks Made from Triblock Copolymers

1996 ◽  
Vol 29 (19) ◽  
pp. 6165-6174 ◽  
Author(s):  
S. Westermann ◽  
V. Urban ◽  
W. Pyckhout-Hintzen ◽  
D. Richter ◽  
E. Straube
Keyword(s):  
Triblock Copolymers ◽  
Topological Constraints

Supramolecular ABA Triblock Copolymers via a Polycondensation Approach:  Synthesis, Characterization, and Micelle Formation

2006 ◽  
Vol 39 (4) ◽  
pp. 1569-1576 ◽  
Author(s):  
Michael A. R. Meier ◽  
Daan Wouters ◽  
Christina Ott ◽  
Pierre Guillet ◽  
Charles-André Fustin ◽  
...  
Keyword(s):  
Triblock Copolymers ◽  
Micelle Formation

Polyethylene Oxide-Polystyrene Oxide Triblock Copolymers as Biological-Responsive Nanocarriers.

2012 ◽  
Vol 1468 ◽  
Author(s):  
Adriana Cambón ◽  
Ana Rey-Rico ◽  
Silvia Barbosa ◽  
Jose Brea ◽  
M. I. Loza ◽  
...  
Keyword(s):  
Cell Line ◽  
Polyethylene Oxide ◽  
Triblock Copolymers ◽  
Styrene Oxide ◽  
Temporal Stability ◽  
Tumor Cell Line ◽  
Micelle Formation ◽  
Multidrug Resistant ◽  
Drug Release Profile

ABSTRACTThe present work presents the synthesis, characterization and evaluation of the biocompatibility and ability to dissolve and chemically protect the anticancer drug doxorubicin (DOXO) of two polyethylene oxide-polystyrene oxide triblock copolymers, EO33SO13EO33 and EO38SO10EO38, where EO and SO denote the ethylene oxide and styrene oxide blocks, respectively. Block copolymer length and SO/EO ratio were selected with the objective of ensuring an optimal compromise between chain solubility, micelle formation ability and core size for enhanced drug solubilization. The temporal stability of the drug-loaded micelles and drug release profile were also analyzed as well as their efficacy as an antitumoral polymeric formulation in vitro by using a multidrug resistant ovarian tumor cell line (NCI-ADR-RES), with the special aim of analyzing the possible capability of both copolymers as potential P-glycoprotein efflux (P-gp) pump inhibitors to enhance DOXO accumulation in this cell line.

Micelle formation of BAB triblock copolymers in solvents that preferentially dissolve the A block

1991 ◽  
Vol 24 (8) ◽  
pp. 1975-1986 ◽  
Author(s):  
N. P. Balsara ◽  
M. Tirrell ◽  
T. P. Lodge
Keyword(s):  
Triblock Copolymers ◽  
Micelle Formation
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