Interactions of synthetic polymers with cell membranes and model membrane systems. Part 6. Disruption of phospholipid packing by branched poly(ethylenimine) derivatives

1985 ◽  
Vol 18 (3) ◽  
pp. 338-342 ◽  
Author(s):  
Doreen Y. Takigawa ◽  
David A. Tirrell
Keyword(s):  
Cell Membranes ◽  
Synthetic Polymers ◽  
Model Membrane ◽  
Membrane Systems

scholarly journals Bioinspired membrane-based systems for a physical approach of cell organization and dynamics: usefulness and limitations

2015 ◽  
Vol 5 (4) ◽  
pp. 20150038 ◽  
Author(s):  
Thibaut J. Lagny ◽  
Patricia Bassereau
Keyword(s):  
Cell Membranes ◽  
Cell Communication ◽  
Basic Research ◽  
Model Membrane ◽  
Membrane Systems ◽  
Vital Functions ◽  
Cell Components ◽  
Potential Applications ◽  
Long Time

Being at the periphery of each cell compartment and enclosing the entire cell while interacting with a large part of cell components, cell membranes participate in most of the cell's vital functions. Biologists have worked for a long time on deciphering how membranes are organized, how they contribute to trafficking, motility, cytokinesis, cell–cell communication, information transport, etc., using top-down approaches and always more advanced techniques. In contrast, physicists have developed bottom-up approaches and minimal model membrane systems of growing complexity in order to build up general models that explain how cell membranes work and how they interact with proteins, e.g. the cytoskeleton. We review the different model membrane systems that are currently available, and how they can help deciphering cell functioning, but also list their limitations. Model membrane systems are also used in synthetic biology and can have potential applications beyond basic research. We discuss the possible synergy between the development of complex in vitro membrane systems in a biological context and for technological applications. Questions that could also be discussed are: what can we still do with synthetic systems, where do we stop building up and which are the alternative solutions?

scholarly journals On scattered waves and lipid domains: detecting membrane rafts with X-rays and neutrons

Soft Matter ◽  
2015 ◽  
Vol 11 (47) ◽  
pp. 9055-9072 ◽  
Author(s):  
Drew Marquardt ◽  
Frederick A. Heberle ◽  
Jonathan D. Nickels ◽  
Georg Pabst ◽  
John Katsaras
Keyword(s):  
Cell Membranes ◽  
Model Membrane ◽  
Biological Role ◽  
Membrane Rafts ◽  
Lipid Domains ◽  
X Rays ◽  
Membrane Systems ◽  
Mesoscopic Structure

In order to understand the biological role of lipids in cell membranes, it is necessary to determine the mesoscopic structure of well-defined model membrane systems.

How does Amphotericin B Work?: Studies on Model Membrane Systems

1993 ◽  
Vol 3 (3) ◽  
pp. 377-408 ◽  
Author(s):  
Scott C. Hartsel ◽  
Christopher Hatch ◽  
Woubeshet Ayenew
Keyword(s):  
Amphotericin B ◽  
Model Membrane ◽  
Membrane Systems

scholarly journals Iron Mediated Interaction of Alpha Synuclein with Lipid Rafts in Model Membrane Systems

2018 ◽  
Vol 114 (3) ◽  
pp. 244a
Author(s):  
Loredana Casalis ◽  
Fabio Perissinotto ◽  
Denis Scaini
Keyword(s):  
Lipid Rafts ◽  
Alpha Synuclein ◽  
Model Membrane ◽  
Membrane Systems
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