Micellar Solution Properties of Fluorocarbon−Hydrocarbon Hybrid Surfactants

Langmuir ◽  
1996 ◽  
Vol 12 (24) ◽  
pp. 5768-5772 ◽  
Author(s):  
Atsushi Ito ◽  
Hideki Sakai ◽  
Yukishige Kondo ◽  
Norio Yoshino ◽  
Masahiko Abe
2020 ◽  
Vol 27 (12) ◽  
Author(s):  
A. A. Lezov ◽  
P. A. Fetin ◽  
A. S. Gubarev ◽  
A. A. Lezova ◽  
O. S. Vezo ◽  
...  

Langmuir ◽  
1998 ◽  
Vol 14 (7) ◽  
pp. 1618-1636 ◽  
Author(s):  
Anat Shiloach ◽  
Daniel Blankschtein

1989 ◽  
Vol 177 ◽  
Author(s):  
Daniel Blankschtein ◽  
Sudhakar Puvvada

IntroductionIn this paper we present a conceptual overview of our recently developed molecular-thermodynamic approach to predict micellization, thermodynamic properties, and phase separation of micellar solutions. A detailed exposition may be found in Ref..


Langmuir ◽  
2005 ◽  
Vol 21 (4) ◽  
pp. 1647-1660 ◽  
Author(s):  
Vibha Srinivasan ◽  
Daniel Blankschtein

Author(s):  
Md. Hamidul Kabir ◽  
Ravshan Makhkamov ◽  
Shaila Kabir

The solution properties and phase behavior of ammonium hexylene octyl succinate (HOS) was investigated in water and water-oil system. The critical micelle concentration (CMC) of HOS is lower than that of anionic surfactants having same carbon number in the lipophilic part. The phase diagrams of a water/ HOS system and water/ HOS/ C10EO8/ dodecane system were also constructed. Above critical micelle concentration, the surfactant forms a normal micellar solution (Wm) at a low surfactant concentration whereas a lamellar liquid crystalline phase (La) dominates over a wide region through the formation of a two-phase region (La+W) in the binary system. The lamellar phase is arranged in the form of a biocompatible vesicle which is very significant for the drug delivery system. The surfactant tends to be hydrophilic when it is mixed with C10EO8 and a middle-phase microemulsion (D) is appeared in the water-surfactant-dodecane system where both the water and oil soluble drug ingredient can be incorporated in the form of a dispersion. Hence, mixing can tune the hydrophile-lipophile properties of the surfactant. Key words: Ammonium hexylene octyl succinate, mixed surfactant, lamellar liquid crystal, middle-phase microemulsion. Dhaka Univ. J. Pharm. Sci. Vol.3(1-2) 2004 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website


2019 ◽  
Vol 16 (10) ◽  
pp. 913-922 ◽  
Author(s):  
Ramprasath Ramakrishnan ◽  
Jolius Gimbun ◽  
Praveen Ramakrishnan ◽  
Balu Ranganathan ◽  
Samala Murali Mohan Reddy ◽  
...  

Background: This paper presents the effect of solution properties and operating parameters of polyethylene oxide (PEO) based nanofiber using a wire electrode-based needleless electrospinning. Methods: The feed solution was prepared using a PEO dissolved in water or a water-ethanol mixture. The PEO solution is blended with Bovine Serum Albumin protein (BSA) as a model drug to study the effect of the electrospinning process on the stability of the loaded protein. The polymer solution properties such as viscosity, surface tension, and conductivity were controlled by adjusting the solvent and salt content. The morphology and fiber size distribution of the nanofiber was analyzed using scanning electron microscopy. Results: The results show that the issue of a beaded nanofiber can be eliminated either by increasing the solution viscosity or by the addition of salt and ethanol to the PEO-water system. The addition of salt and solvent produced a high frequency of smaller fiber diameter ranging from 100 to 150 nm. The encapsulation of BSA in PEO nanofiber was characterized by three different spectroscopy techniques (i.e. circular dichroism, Fourier transform infrared, and fluorescence) and the results showed the BSA is well encapsulated in the PEO matrix with no changes in the protein structure. Conclusion: This work may serve as a useful guide for a drug delivery industry to process a nanofiber at a large and continuous scale with a blend of drugs in nanofiber using a wire electrode electrospinning.


2000 ◽  
Vol 89 (12) ◽  
pp. 1525-1536 ◽  
Author(s):  
Peter M. Ihnat ◽  
Jonathan L. Vennerstrom ◽  
Dennis H. Robinson
Keyword(s):  

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