pH-Responsive Jello: Gelatin Gels Containing Fatty Acid Vesicles†

Langmuir ◽  
2009 ◽  
Vol 25 (15) ◽  
pp. 8519-8525 ◽  
Author(s):  
Matthew B. Dowling ◽  
Jae-Ho Lee ◽  
Srinivasa R. Raghavan
Keyword(s):  
Fatty Acid ◽  
Ph Responsive ◽  
Gelatin Gels

Novel fatty acid-based pH-responsive nanostructured lipid carriers for enhancing antibacterial delivery

2019 ◽  
Vol 53 ◽  
pp. 101125 ◽  
Author(s):  
Nawras Osman ◽  
Calvin A. Omolo ◽  
Ramesh Gannimani ◽  
Ayman Y. Waddad ◽  
Sanjeev Rambharose ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Nanostructured Lipid Carriers ◽  
Ph Responsive

DAP derived fatty acid amide organogelators as novel carrier for drug incorporation and pH-responsive release

2021 ◽  
Vol 45 (1) ◽  
pp. 415-422
Author(s):  
Eqvinshi Yadav ◽  
Anil Kumar Khatana ◽  
Sharol Sebastian ◽  
Manoj K. Gupta
Keyword(s):  
Fatty Acid ◽  
Molecular Mass ◽  
Acid Amide ◽  
Ph Responsive ◽  
Alkyl Chains ◽  
Drug Incorporation ◽  
Structure And Activity ◽  
Fatty Acid Amide

Low-molecular mass fatty acid amide gelators were synthesized using 2,6-diaminopyridine as a linker and alkyl chains of varying lengths. The prepared organogel-elusions are able to trap and release ibuprofen molecule without changing its structure and activity.

Characterization of pH-Responsive Self-Assembly Behaviors of Fatty Acid-Functionalized Prodrug

2020 ◽  
Vol 164 ◽  
pp. 107794
Author(s):  
Jin Han ◽  
Keita Hayashi ◽  
Yukihiro Okamoto ◽  
Keishi Suga ◽  
Hiroshi Umakoshi
Keyword(s):  
Fatty Acid ◽  
Self Assembly ◽  
Ph Responsive

Enhanced in vitro antitumor efficacy of a polyunsaturated fatty acid-conjugated pH-responsive self-assembled ion-pairing liposome-encapsulated prodrug

2020 ◽  
Vol 31 (15) ◽  
pp. 155101
Author(s):  
Yuxian Wang ◽  
Panpan Fan ◽  
Liying Zhu ◽  
Wei Zhuang ◽  
Ling Jiang ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Ion Pairing ◽  
Antitumor Efficacy ◽  
Ph Responsive ◽  
Self Assembled

Novel lipids with three C18-fatty acid chains and an amino acid head group for pH-responsive and sustained antibiotic delivery

2018 ◽  
Vol 212 ◽  
pp. 12-25 ◽  
Author(s):  
Mahantesh Jadhav ◽  
Rahul S. Kalhapure ◽  
Sanjeev Rambharose ◽  
Chunderika Mocktar ◽  
Sanil Singh ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Amino Acid ◽  
Head Group ◽  
Ph Responsive ◽  
Antibiotic Delivery

Structural Effects and Lipid Membrane Interactions of the pH-Responsive GALA Peptide with Fatty Acid Acylation

Biochemistry ◽  
2012 ◽  
Vol 51 (23) ◽  
pp. 4658-4668 ◽  
Author(s):  
Brian F. Lin ◽  
Dimitris Missirlis ◽  
Daniel V. Krogstad ◽  
Matthew Tirrell
Keyword(s):  
Fatty Acid ◽  
Lipid Membrane ◽  
Ph Responsive ◽  
Structural Effects ◽  
Membrane Interactions

scholarly journals pH-Responsive Nanostructures Based on Surface Active Fatty Acid-Protic Ionic Liquids for Imiquimod Delivery in Skin Cancer Topical Therapy

Pharmaceutics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1078
Author(s):  
Silvia Tampucci ◽  
Lorenzo Guazzelli ◽  
Susi Burgalassi ◽  
Sara Carpi ◽  
Patrizia Chetoni ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ionic Liquids ◽  
Fatty Acid ◽  
Skin Cancer ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ph Responsive ◽  
Protic Ionic Liquids ◽  
Drug Concentrations ◽  
Surface Active

For topical treatment of skin cancer, the design of pH-responsive nanocarriers able to selectively release the drug in the tumor acidic microenvironment represents a reliable option for targeted delivery. In this context, a series of newly synthesized surface-active fatty acid-protic ionic liquids (FA-PILs), based on tetramethylguanidinium cation and different natural hydrophobic fatty acid carboxylates, have been investigated with the aim of developing a pH-sensitive nanostructured drug delivery system for cutaneous administration in the skin cancer therapy. The capability of FA-PILs to arrange in micelles when combined with each other and with the non-ionic surfactant d-α-Tocopherol polyethylene glycol succinate (vitamin E TPGS) as well as their ability to solubilize imiquimod, an immuno-stimulant drug used for the treatment of skin cancerous lesions, have been demonstrated. The FA-PILs-TPGS mixed micelles showed pH-sensitivity, suggesting that the acidic environment of cancer cells can trigger nanostructures’ swelling and collapse with consequent rapid release of imiquimod and drug cytotoxic potential enhancement. The in vitro permeation/penetration study showed that the micellar formulation produced effective imiquimod concentrations into the skin exposed to acid environment, representing a potential efficacious and selective drug delivery system able to trigger the drug release in the tumor tissues, at lower and less irritating drug concentrations.

scholarly journals pH-responsive Liquid Marbles Prepared Using Fluorinated Fatty Acid

2016 ◽  
Vol 45 (5) ◽  
pp. 547-549 ◽  
Author(s):  
Sayaka Ohno ◽  
Yoshihiro Tsuda ◽  
Keita Nakai ◽  
Syuji Fujii ◽  
Yoshinobu Nakamura ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Ph Responsive ◽  
Liquid Marbles
Sign in / Sign up

Export Citation Format

Share Document