Increased Drop Formation Frequency via Reduction of Surfactant Interactions in Flow-Focusing Microfluidic Devices

Langmuir ◽  
2015 ◽  
Vol 31 (3) ◽  
pp. 1218-1224 ◽  
Author(s):  
Dimitris N. Josephides ◽  
Shahriar Sajjadi
Keyword(s):  
Microfluidic Devices ◽  
Drop Formation ◽  
Flow Focusing ◽  
Surfactant Interactions

Design, characterization and application of a novel mono-layer pin-microvalve for microfluidic devices

RSC Advances ◽  
2014 ◽  
Vol 4 (46) ◽  
pp. 24394-24398 ◽  
Author(s):  
Mahyar Nasabi ◽  
Masoomeh Tehranirokh ◽  
Francisco Javier Tovar-Lopez ◽  
Abbas Kouzani ◽  
Khashayar Khoshmanesh ◽  
...  
Keyword(s):  
Microfluidic Devices ◽  
Hydrodynamic Flow ◽  
Flow Focusing ◽  
Mono Layer

We introduce a novel manual pin-valve which can operate in both analogue (partially close) and digital (on/off) states. We also demonstrate implementation of this pin-valve in a hydrodynamic flow focusing (HFF) device.

scholarly journals Coaxial flow focusing in poly(dimethylsiloxane) microfluidic devices

2014 ◽  
Vol 8 (1) ◽  
pp. 016502 ◽  
Author(s):  
Tuan M. Tran ◽  
Sean Cater ◽  
Adam R. Abate
Keyword(s):  
Microfluidic Devices ◽  
Flow Focusing

Fab in a Package: LTCC Microfluidic Devices for Micro and Nanoparticle Fabrication

2012 ◽  
Vol 2012 (CICMT) ◽  
pp. 000294-000302
Author(s):  
Mário Ricardo Gongora-Rubio ◽  
Kellen Heloizy Garcia Freitas ◽  
Juliana de Novais Schianti ◽  
Adriano Marim de Oliveira ◽  
Natália Neto Pereira Cerize ◽  
...  
Keyword(s):  
Energy Use ◽  
Microfluidic Devices ◽  
Chemical Processes ◽  
Mass Transportation ◽  
Flow Focusing ◽  
Automated Control ◽  
Microreaction Technology ◽  
Relevant Role ◽  
Excellent Control ◽  
Nanoparticle Fabrication

The chemical industry is moving toward miniaturization with the help of microreaction technology and automated control systems. Besides the evident advantages of Microtechnology like improved portability, reduced energy use, safety and flexibility, the main advantage associated with the miniaturization of chemical processes is the increased microreactor control due to predictable thermal and mass transportation properties. We understand that LTCC Microsystem technology have a relevant role in this area. LTCC Microfluidic devices have been applied to carry out several chemical processes operations, including mixing, separation, chemical reactions, heterogeneous catalysis, heat exchange and so on. More recently, LTCC microfluidic systems have also been used to produce micro- and nanoparticles with excellent control of size distribution, morphology and constitution. The present work give an account of some LTCC Microfluidic devices aimed for Micro and Nanoparticle fabrication. At this time we report devices for: Emulsion generation for obtaining alginate microparticles by ionic gelation; Electrospinning applications, Microreactors for silver nanoparticle production and 3D Flow focusing devices for pharmaceutical active nanocrystallization.

High-throughput continuous production of liposomes using hydrodynamic flow-focusing microfluidic devices

2017 ◽  
Vol 156 ◽  
pp. 349-357 ◽  
Author(s):  
Mariano Michelon ◽  
Davi Rocha Bernardes Oliveira ◽  
Guilherme de Figueiredo Furtado ◽  
Lucimara Gaziola de la Torre ◽  
Rosiane Lopes Cunha
Keyword(s):  
High Throughput ◽  
Continuous Production ◽  
Microfluidic Devices ◽  
Hydrodynamic Flow ◽  
Flow Focusing

A Computational Study of Drop Formation in an Axisymmetric Flow-Focusing Device

2006 ◽  
Author(s):  
Ismail Filiz ◽  
Metin Muradoglu
Keyword(s):  
Drop Size ◽  
Viscosity Ratio ◽  
Computational Study ◽  
Axisymmetric Flow ◽  
Front Tracking ◽  
Drop Formation ◽  
Flow Focusing ◽  
Outer Flow ◽  
Flow Rates ◽  
Creation Process

We investigate the formation and dynamics of drops computationally in an axisymetric geometry using a Front-Tracking/Finite-Difference (FT/FD) method. The effects of viscosity ratio between inner and outer liquids on the drop creation process and drop size distribution are examined. It is found that the viscosity ratio critically influences the drop formation process and the final drop distribution. We found that, for small viscosity ratios, i.e., 0.1 < λ < 0.5 drop size is about the size of the orifice and drop distribution is highly monodisperse. When viscosity ratio is increased, i.e., 0.5 < λ < 1 a smaller drop is created just after the main drop. For even higher viscosity ratios, the drop distribution is usually monodisperse but a satellite drop is created in some cases. The effect of the flow rates in the inner jet and the co flowing annulus are also studied. It is found that the drop size gets smaller as Qin / Qout is reduced while keeping the outer flow rate constant.

Analytical Study of the Instability Between Two Liquids Flowing in a Channel and Subjected to Parallel or Normal Electric Field

2008 ◽  
Author(s):  
A. Kerem Uguz ◽  
Nadine Aubry
Keyword(s):  
Electric Field ◽  
Analytical Study ◽  
Microfluidic Devices ◽  
Maximum Growth ◽  
Drop Formation ◽  
Plane Poiseuille Flow ◽  
Flat Interface ◽  
Material Deposition ◽  
Normal Electric Field ◽  
Complete Set

The electro-hydrodynamic linear stability of a flat interface between two viscous, immiscible and incompressible liquids in plane Poiseuille flow has been shown to be useful in microfluidic devices. In some applications (e.g., material deposition) stability is desired, and in others (e.g., mixing or drop formation) instability needs to be induced. Depending on the direction of the electric field, i.e., parallel or normal to the flat interface, and in the case of fast electric times, it was shown analytically and without solving the complete set of equations that the electric field can either stabilize or destabilize the interface [1]. In this paper, we fully solve the equations and determine the maximum growth rates and the critical wavenumbers in the conductivity versus permittivity ratio space.

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