PEGylation of Phytantriol-Based Lyotropic Liquid Crystalline Particles—The Effect of Lipid Composition, PEG Chain Length, and Temperature on the Internal Nanostructure

Langmuir ◽  
2014 ◽  
Vol 30 (22) ◽  
pp. 6398-6407 ◽  
Author(s):  
Christa Nilsson ◽  
Jesper Østergaard ◽  
Susan Weng Larsen ◽  
Claus Larsen ◽  
Arto Urtti ◽  
...  
Keyword(s):  
Chain Length ◽  
Lipid Composition ◽  
Liquid Crystalline ◽  
Peg Chain Length

Shielding effect of a PEG molecule of a mono-PEGylated peptide varies with PEG chain length

2018 ◽  
Vol 48 (6) ◽  
pp. 522-527 ◽  
Author(s):  
Ngoc-Thanh Thi Nguyen ◽  
Soi Yun ◽  
Dong Woo Lim ◽  
E. K. Lee
Keyword(s):  
Chain Length ◽  
Shielding Effect ◽  
Peg Chain Length

Impact of PEG Chain Length on the Physical Properties and Bioactivity of PEGylated Chitosan/siRNA Nanoparticles in Vitro and in Vivo

2017 ◽  
Vol 9 (14) ◽  
pp. 12203-12216 ◽  
Author(s):  
Chuanxu Yang ◽  
Shan Gao ◽  
Frederik Dagnæs-Hansen ◽  
Maria Jakobsen ◽  
Jørgen Kjems
Keyword(s):  
Physical Properties ◽  
Chain Length ◽  
Peg Chain Length

Star mesogens — Synthesis and structural characterization using 1D and 2D solution NMR techniques and mesophase characterization

2013 ◽  
Vol 91 (3) ◽  
pp. 196-205 ◽  
Author(s):  
A. Shanavas ◽  
T. Narasimhaswamy ◽  
B.V.N. Phani Kumar ◽  
A. Sultan Nasar
Keyword(s):  
Chain Length ◽  
Liquid Crystalline ◽  
Variable Temperature ◽  
2D Nmr ◽  
Smectic Layer ◽  
X Ray Diffraction ◽  
Scanning Calorimetry ◽  
X Ray ◽  
Xrd Techniques ◽  
Terminal Chain

Novel star mesogens based on trimesic acid and symmetrical side arm cores with terminal alkoxy groups were synthesized via a divergent approach. The central core and side arms were connected through alkyl spacers. All the synthesized mesogens and their intermediates were characterized thoroughly using Fourier transform infrared (FT-IR), 1H nuclear magnetic resonance (NMR), 13C NMR, and mass spectrometers. One representative mesogen was subjected to the two-dimensional (2D) NMR experiments to ascertain the structure of the mesogens. The mesophase characterization was carried out using hot-stage optical polarizing microscopy (HOPM), differential scanning calorimetry (DSC), and X-ray diffraction (XRD) techniques. Many of the molecules with an ethyloxy spacer were found to be nonmesogenic, whereas all the molecules with a butyloxy spacer showed liquid crystalline phases. The increase of terminal chain length decreased the transition temperatures. The nematic phase was observed for the mesogens with short terminal chain length, whereas smectic polymorphism was observed on increasing the terminal chain length. The results of a variable temperature powder X-ray diffraction of the representative sample support the smectic layer ordering.

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