Mapping the Mechanical Properties of Cholesterol-Containing Supported Lipid Bilayers with Nanoscale Spatial Resolution

Langmuir ◽  
2012 ◽  
Vol 28 (37) ◽  
pp. 13411-13422 ◽  
Author(s):  
Nicole Shamitko-Klingensmith ◽  
Kelley M. Molchanoff ◽  
Kathleen A. Burke ◽  
George J. Magnone ◽  
Justin Legleiter
Keyword(s):  
Mechanical Properties ◽  
Lipid Bilayers ◽  
Spatial Resolution ◽  
Supported Lipid Bilayers

Molecular diffusion and nano-mechanical properties of multi-phase supported lipid bilayers

2019 ◽  
Vol 21 (30) ◽  
pp. 16686-16693 ◽  
Author(s):  
Tatsuhiro Maekawa ◽  
Hokyun Chin ◽  
Takashi Nyu ◽  
Tun Naw Sut ◽  
Abdul Rahim Ferhan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Lipid Bilayers ◽  
Cell Membranes ◽  
Molecular Diffusion ◽  
Supported Lipid Bilayers ◽  
Multi Phase ◽  
Applied Biology

Understanding the properties of cell membranes is important in the fields of fundamental and applied biology.

Agar-supported lipid bilayers — basic structures for biosensor design. Electrical and mechanical properties

1998 ◽  
Vol 140 (1-3) ◽  
pp. 357-367 ◽  
Author(s):  
W Ziegler ◽  
J Gaburjáková ◽  
M Gaburjáková ◽  
B Sivák ◽  
V Řehaček ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Lipid Bilayers ◽  
Supported Lipid Bilayers

Dynamic and mechanical properties of supported lipid bilayers

2016 ◽  
Vol 144 (15) ◽  
pp. 154904 ◽  
Author(s):  
Hsing-Lun Wu ◽  
Heng-Kwong Tsao ◽  
Yu-Jane Sheng
Keyword(s):  
Mechanical Properties ◽  
Lipid Bilayers ◽  
Supported Lipid Bilayers

Spatial-Resolution Limits in Mass Spectrometry Imaging of Supported Lipid Bilayers and Individual Lipid Vesicles

2010 ◽  
Vol 82 (6) ◽  
pp. 2426-2433 ◽  
Author(s):  
Anders Gunnarsson ◽  
Felix Kollmer ◽  
Sascha Sohn ◽  
Fredrik Höök ◽  
Peter Sjövall
Keyword(s):  
Mass Spectrometry ◽  
Lipid Bilayers ◽  
Spatial Resolution ◽  
Mass Spectrometry Imaging ◽  
Lipid Vesicles ◽  
Supported Lipid Bilayers ◽  
Resolution Limits

Influence of Brain Gangliosides on the Formation and Properties of Supported Lipid Bilayers for Binding Kinetics Studies

2018 ◽  
Author(s):  
Luke Jordan ◽  
Nathan Wittenberg
Keyword(s):  
Lipid Bilayers ◽  
Binding Kinetics ◽  
Supported Lipid Bilayers ◽  
Dependent Manner ◽  
Concentration Dependent Manner ◽  
Supported Lipid Bilayer ◽  
Head Groups ◽  
Lipid Diffusion ◽  
Kinetics Of ◽  
Brain Gangliosides

This is a comprehensive study of the effects of the four major brain gangliosides (GM1, GD1b, GD1a, and GT1b) on the adsorption and rupture of phospholipid vesicles on SiO2 surfaces for the formation of supported lipid bilayer (SLB) membranes. Using quartz crystal microbalance with dissipation monitoring (QCM-D) we show that gangliosides GD1a and GT1b significantly slow the SLB formation process, whereas GM1 and GD1b have smaller effects. This is likely due to the net ganglioside charge as well as the positions of acidic sugar groups on ganglioside glycan head groups. Data is included that shows calcium can accelerate the formation of ganglioside-rich SLBs. Using fluorescence recovery after photobleaching (FRAP) we also show that the presence of gangliosides significantly reduces lipid diffusion coefficients in SLBs in a concentration-dependent manner. Finally, using QCM-D and GD1a-rich SLB membranes we measure the binding kinetics of an anti-GD1a antibody that has similarities to a monoclonal antibody that is a hallmark of a variant of Guillain-Barre syndrome.

scholarly journals Silica nanoparticle supported lipid bilayers for gene delivery

2009 ◽  
pp. 5100 ◽  
Author(s):  
Juewen Liu ◽  
Alison Stace-Naughton ◽  
C. Jeffrey Brinker
Keyword(s):  
Gene Delivery ◽  
Lipid Bilayers ◽  
Silica Nanoparticle ◽  
Supported Lipid Bilayers

scholarly journals Formation of Supported Lipid Bilayers Derived from Vesicles of Various Compositional Complexity on Conducting Polymer/Silica Substrates

Langmuir ◽  
2021 ◽  
Author(s):  
Hanna Ulmefors ◽  
Josefin Nissa ◽  
Hudson Pace ◽  
Olov Wahlsten ◽  
Anders Gunnarsson ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Conducting Polymer ◽  
Supported Lipid Bilayers ◽  
Silica Substrates
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