Dextran Coatings for Aggregation Control of Layer-by-Layer Assembled Polyelectrolyte Microcapsules

Langmuir ◽  
2010 ◽  
Vol 26 (15) ◽  
pp. 12575-12584 ◽  
Author(s):  
Denys Usov ◽  
Gleb B. Sukhorukov
Keyword(s):  
Layer By Layer ◽  
Polyelectrolyte Microcapsules ◽  
Aggregation Control

scholarly journals Facile fabrication of luminescent organic dots by thermolysis of citric acid in urea melt, and their use for cell staining and polyelectrolyte microcapsule labelling

2016 ◽  
Vol 7 ◽  
pp. 1905-1917 ◽  
Author(s):  
Nadezhda M Zholobak ◽  
Anton L Popov ◽  
Alexander B Shcherbakov ◽  
Nelly R Popova ◽  
Mykhailo M Guzyk ◽  
...  
Keyword(s):  
Citric Acid ◽  
Solvent Free ◽  
Layer By Layer ◽  
One Pot ◽  
Polyelectrolyte Microcapsules ◽  
Cell Staining ◽  
Polyelectrolyte Microcapsule ◽  
Facile Fabrication ◽  
Fixed Cell

Luminescent organic dots (O-dots) were synthesized via a one-pot, solvent-free thermolysis of citric acid in urea melt. The influence of the ratio of the precursors and the duration of the process on the properties of the O-dots was established and a mechanism of their formation was hypothesized. The multicolour luminescence tunability and toxicity of synthesized O-dots were extensively studied. The possible applications of O-dots for alive/fixed cell staining and labelling of layer-by-layer polyelectrolyte microcapsules were evaluated.

Layer-by-layer engineered polyelectrolyte microcapsules studied by ToF-SIMS and related analytical techniques

2010 ◽  
Vol 43 (1-2) ◽  
pp. 649-653 ◽  
Author(s):  
Yu-Sheng Yin ◽  
Shiou-Ling Lei ◽  
Yu-Wen Chen ◽  
Yong-Chien Ling
Keyword(s):  
Analytical Techniques ◽  
Layer By Layer ◽  
Polyelectrolyte Microcapsules ◽  
Tof Sims

scholarly journals pH-Dependent Release of Insulin from Layer-by-Layer-Deposited Polyelectrolyte Microcapsules

Polymers ◽  
2015 ◽  
Vol 7 (7) ◽  
pp. 1269-1278 ◽  
Author(s):  
Kentaro Yoshida ◽  
Tetsuya Ono ◽  
Yoshitomo Kashiwagi ◽  
Shigehiro Takahashi ◽  
Katsuhiko Sato ◽  
...  
Keyword(s):  
Layer By Layer ◽  
Polyelectrolyte Microcapsules ◽  
Ph Dependent

scholarly journals Janus-micromotor-based on–off luminescence sensor for active TNT detection

2019 ◽  
Vol 10 ◽  
pp. 1324-1331 ◽  
Author(s):  
Ye Yuan ◽  
Changyong Gao ◽  
Daolin Wang ◽  
Chang Zhou ◽  
Baohua Zhu ◽  
...  
Keyword(s):  
Reaction Rate ◽  
Limit Of Detection ◽  
Catalytic Decomposition ◽  
Contaminated Water ◽  
Layer By Layer ◽  
Bubble Generation ◽  
Polyelectrolyte Microcapsules ◽  
Platinum Layer ◽  
Tnt Detection ◽  
Layer Assembly

An active TNT (2,4,6-trinitrotoluene) catalytic sensor based on Janus upconverting nanoparticle (UCNP)-functionalized micromotor capsules, displaying “on–off” luminescence with a low limit of detection has been developed. The Janus capsule motors were fabricated by layer-by-layer assembly of UCNP-functionalized polyelectrolyte microcapsules, followed by sputtering of a platinum layer onto one half of the capsule. By catalytic decomposition of hydrogen peroxide to oxygen bubbles, the Janus UCNP capsule motors are rapidly propelled with a speed of up to 110 μm s−1. Moreover, the Janus motors display efficient on–off luminescent detection of TNT. Owing to the unique motion of the Janus motor with bubble generation, the likelihood of collision with TNT molecules and the reaction rate between them are increased, resulting in a limit of detection as low as 2.4 ng mL−1 TNT within 1 minute. Such bubble-propelled Janus UCNP capsule motors have great potential for contaminated water analysis.

Gene delivery using biodegradable polyelectrolyte microcapsules prepared through the layer-by-layer technique

2012 ◽  
Vol 28 (4) ◽  
pp. 1088-1094 ◽  
Author(s):  
José L. Santos ◽  
Alireza Nouri ◽  
Tiago Fernandes ◽  
João Rodrigues ◽  
Helena Tomás
Keyword(s):  
Gene Delivery ◽  
Layer By Layer ◽  
Polyelectrolyte Microcapsules ◽  
Layer Technique ◽  
Layer By Layer Technique

scholarly journals Biofunctionalized Polyelectrolyte Microcapsules Encoded with Fluorescent Semiconductor Nanocrystals for Highly Specific Targeting and Imaging of Cancer Cells

Photonics ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 117 ◽  
Author(s):  
Galina Nifontova ◽  
Daria Kalenichenko ◽  
Maria Baryshnikova ◽  
Fernanda Ramos Gomes ◽  
Frauke Alves ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Size Structure ◽  
Semiconductor Nanocrystals ◽  
Transport Processes ◽  
The Body ◽  
Water Soluble ◽  
Fluorescence Signal ◽  
Layer By Layer ◽  
Polyelectrolyte Microcapsules ◽  
Fluorescent Semiconductor Nanocrystals

Fluorescent semiconductor nanocrystals or quantum dots (QDs) are characterized by unique optical properties, including a high photostability, wide absorption spectrum, and narrow, symmetric fluorescence spectrum. This makes them attractive fluorescent nanolabels for the optical encoding of microcarriers intended for targeted drug delivery, diagnosis, and imaging of transport processes on the body, cellular, and subcellular levels. Incorporation of QDs into carriers in the form of polyelectrolyte microcapsules through layer-by-layer adsorption of oppositely charged polyelectrolyte polymers yields microcapsules with a bright fluorescence signal and adaptable size, structure, and surface characteristics without using organic solvents. The easily modifiable surface of the microcapsules allows for its subsequent functionalization with capture molecules, such as antibodies, which ensures specific and selective interaction with cells, including tumor cells, with the use of the bioconjugation technique developed here. We obtained stable water-soluble nanolabels based on QDs whose surface was modified with polyethylene glycol (PEG) derivatives and determined their colloidal and optical characteristics. The obtained nanocrystals were used to encode polyelectrolyte microcapsules optically. The microcapsule surface was modified with humanized monoclonal antibodies (Abs) recognizing a cancer marker, epidermal growth factor receptor (EGFR). The possibility of effective, specific, and selective delivery of the microcapsules to tumor cells expressing EGFR has been demonstrated. The results show that the QD-encoded polyelectrolyte microcapsules functionalized with monoclonal Abs against EGFR can be used for targeted imaging and diagnosis.

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