Gene delivery using biodegradable polyelectrolyte microcapsules prepared through the layer-by-layer technique

2012 ◽  
Vol 28 (4) ◽  
pp. 1088-1094 ◽  
Author(s):  
José L. Santos ◽  
Alireza Nouri ◽  
Tiago Fernandes ◽  
João Rodrigues ◽  
Helena Tomás
Keyword(s):  
Gene Delivery ◽  
Layer By Layer ◽  
Polyelectrolyte Microcapsules ◽  
Layer Technique ◽  
Layer By Layer Technique

scholarly journals Gene delivery using dendrimer/pDNA complexes immobilized in electrospun fibers using the Layer-by-Layer technique

RSC Advances ◽  
2016 ◽  
Vol 6 (99) ◽  
pp. 97116-97128 ◽  
Author(s):  
Kirthiga Ramalingam ◽  
Rita Castro ◽  
Pedro Pires ◽  
Xiangyang Shi ◽  
João Rodrigues ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Osteogenic Differentiation ◽  
Electrospun Fibers ◽  
Layer By Layer ◽  
Layer Technique ◽  
Layer By Layer Technique

Dendrimer/pDNA complexes can be immobilized in PLGA fibers through the Layer-by-Layer technique and direct hMSCs towards osteogenic differentiation.

scholarly journals Layer-by-Layer technique as a versatile tool for gene delivery applications

2021 ◽  
pp. 1-19
Author(s):  
Dmitrii S. Linnik ◽  
Yana V. Tarakanchikova ◽  
Mikhail V. Zyuzin ◽  
Kirill V. Lepik ◽  
Joeri L. Aerts ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Layer By Layer ◽  
Layer Technique ◽  
Versatile Tool ◽  
Layer By Layer Technique

Pectin-Chitosan Multilayer Coated Microbeads of Diclofenac Sodium Prepared by Layer-by-Layer Technique

2014 ◽  
Vol 1060 ◽  
pp. 45-49
Author(s):  
Kamonrak Cheewatanakornkool ◽  
Pornsak Sriamornsak
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Diclofenac Sodium ◽  
Gastric Fluid ◽  
Layer By Layer ◽  
Release Behavior ◽  
Freeze Dried ◽  
Layer Technique ◽  
Calcium Pectinate ◽  
Layer By Layer Technique

The main objective of this study was to fabricate biopolymer-based microbeads, providing enteric properties and controlled release of diclofenac sodium, using layer-by-layer technique. The calcium pectinate microbeads have been designed and coated with chitosan and pectin multilayers. Drug release was performed in simulate gastric fluid (pH 1.2) for 2 hours, followed by pH 6.8 buffer for 8 hours. The effects of chitosan concentration, number of layer and drying technique on drug release were investigated. The results showed that the calcium pectinate microbeads could be simply prepared by ionotropic gelation and then coated with chitosan and pectin solutions using layer-by-layer procedure. The diameter of the microbeads ranged from 800 to 1000 μm for air-dried samples and from 1 to 2 mm for freeze-dried samples. The freeze-dried microbeads had a rough surface and many pores inside, as observed by SEM. The microbeads coated with 4% chitosan/4% pectin revealed a slower drug release than those coated with 1% chitosan/4% pectin and demonstrated a controlled release pattern. Moreover, different drying techniques and numbers of layer also influenced drug release behavior of the prepared microbeads.

Highly transparent and self-healing films based on the dynamic Schiff base linkage

RSC Advances ◽  
2016 ◽  
Vol 6 (116) ◽  
pp. 115247-115251 ◽  
Author(s):  
Jiaoyu Ren ◽  
Yanxi Zhu ◽  
Hongyun Xuan ◽  
Xuefan Liu ◽  
Zhichao Lou ◽  
...  
Keyword(s):  
Schiff Base ◽  
Layer By Layer ◽  
Self Healing ◽  
Layer Technique ◽  
Layer By Layer Technique

In this study, we report highly transparent self-healing films based on Schiff base linkages between DF-PEG and CS via a layer-by-layer technique.

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