Attachment of Degradable Poly(Ethylene Glycol) to Proteins has the Potential to Increase Therapeutic Efficacy

Michael J. Roberts; J. Milton Harris

doi:10.1021/js9800634

Attachment of Degradable Poly(Ethylene Glycol) to Proteins has the Potential to Increase Therapeutic Efficacy

Journal of Pharmaceutical Sciences ◽

10.1021/js9800634 ◽

1998 ◽

Vol 87 (11) ◽

pp. 1440-1445 ◽

Cited By ~ 55

Author(s):

Michael J. Roberts ◽

J. Milton Harris

Keyword(s):

Ethylene Glycol ◽

Therapeutic Efficacy ◽

Poly Ethylene Glycol ◽

Poly Ethylene

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Docetaxel-conjugated monomethoxy-poly(ethylene glycol)-b-poly(lactide) (mPEG-PLA) polymeric micelles to enhance the therapeutic efficacy in oral squamous cell carcinoma

RSC Advances ◽

10.1039/c6ra03332f ◽

2016 ◽

Vol 6 (49) ◽

pp. 42819-42826 ◽

Cited By ~ 4

Author(s):

Liang Shi ◽

Xiao-Bin Song ◽

Yong Wang ◽

Ke-Tao Wang ◽

Ping Liu ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Oral Squamous Cell Carcinoma ◽

Ethylene Glycol ◽

Cell Carcinoma ◽

Therapeutic Efficacy ◽

Polymeric Micelles ◽

Poly Ethylene Glycol ◽

Ester Linkage ◽

Poly Ethylene ◽

Polymer Block

In this study, docetaxel (DTX) was successfully conjugated to the monomethoxy-poly(ethylene glycol)-b-poly(lactide) (mPEG-PLA) polymer block via an ester linkage (DTX-PM).

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Poly(ethylene glycol)-Modified PAMAM-Fe3O4-Doxorubicin Triads with the Potential for Improved Therapeutic Efficacy: Generation-Dependent Increased Drug Loading and Retention at Neutral pH and Increased Release at Acidic pH

Langmuir ◽

10.1021/la404246h ◽

2014 ◽

Vol 30 (4) ◽

pp. 1004-1011 ◽

Cited By ~ 30

Author(s):

Saumya Nigam ◽

Sudeshna Chandra ◽

Donald F. Newgreen ◽

Dhirendra Bahadur ◽

Qizhi Chen

Keyword(s):

Ethylene Glycol ◽

Therapeutic Efficacy ◽

Drug Loading ◽

Acidic Ph ◽

Poly Ethylene Glycol ◽

Neutral Ph ◽

Poly Ethylene

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145 POSTER Marked therapeutic efficacy of a novel poly(ethylene-glycol) conjugated SN38 conjugate in xenograft models of breast and colorectal cancers

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(06)70151-3 ◽

2006 ◽

Vol 4 (12) ◽

pp. 47

Author(s):

P. Sapra ◽

C. Longley ◽

Z. Zhang ◽

H. Zhao ◽

B. Rubio ◽

...

Keyword(s):

Ethylene Glycol ◽

Therapeutic Efficacy ◽

Colorectal Cancers ◽

Poly Ethylene Glycol ◽

Xenograft Models ◽

Poly Ethylene

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Gelatinase-stimuli strategy enhances the tumor delivery and therapeutic efficacy of docetaxel-loaded poly(ethylene glycol)-poly(ε-caprolactone) nanoparticles

International Journal of Nanomedicine ◽

10.2147/ijn.s26697 ◽

2012 ◽

pp. 281 ◽

Cited By ~ 26

Author(s):

Bao-Rui Liu

Keyword(s):

Ethylene Glycol ◽

Therapeutic Efficacy ◽

Poly Ethylene Glycol ◽

Tumor Delivery ◽

Poly Ethylene

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Therapeutic Efficacy of Nanocomplex of Poly(Ethylene Glycol) and Catechin for Dry Eye Disease in a Mouse Model

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.16-20843 ◽

2017 ◽

Vol 58 (3) ◽

pp. 1682 ◽

Cited By ~ 13

Author(s):

Hyesook Lee ◽

Whuisu Shim ◽

Chae Eun Kim ◽

So Yeon Choi ◽

Haeshin Lee ◽

...

Keyword(s):

Mouse Model ◽

Ethylene Glycol ◽

Dry Eye ◽

Therapeutic Efficacy ◽

Dry Eye Disease ◽

Eye Disease ◽

Poly Ethylene Glycol ◽

Poly Ethylene

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Poly(ethylene glycol)-block-poly(ε-caprolactone)– and phospholipid-based stealth nanoparticles with enhanced therapeutic efficacy on murine breast cancer by improved intracellular drug delivery

International Journal of Nanomedicine ◽

10.2147/ijn.s75186 ◽

2015 ◽

pp. 1791 ◽

Cited By ~ 5

Author(s):

Li Li ◽

Xiaodan He ◽

Hong Su ◽

Dinglun Zhou ◽

Hongmei Song ◽

...

Keyword(s):

Breast Cancer ◽

Drug Delivery ◽

Ethylene Glycol ◽

Therapeutic Efficacy ◽

Poly Ethylene Glycol ◽

Intracellular Drug Delivery ◽

Poly Ethylene ◽

Stealth Nanoparticles

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PIEZOELECTRIC PROPERTIES OF POLY(3-HYDROXYBUTYRATE-CO-3-HEDROXYBUTYRATE)-CO-POLY(ETHYLENE GLYCOL) PRODUCED BY CONTROLLED MICROBIOLOGICAL BIOSYNTHESIS

Biological journal ◽

10.32743/2658-6460.2019.10.10.184 ◽

2019 ◽

Vol 10 (10) ◽

Author(s):

Anton Bonartsev ◽

Vera Voinova ◽

Elizaveta Akoulina ◽

Andrey Dudun ◽

Irina Zharkova ◽

...

Keyword(s):

Ethylene Glycol ◽

Piezoelectric Properties ◽

Poly Ethylene Glycol ◽

Poly Ethylene

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Thermosensitives hydrogels based on poly (ethylene glycol): I. Synthesis, characterization and release

Annales de Chimie Science des Matériaux ◽

10.3166/acsm.32.431-446 ◽

2007 ◽

Vol 32 (5) ◽

pp. 431-446 ◽

Cited By ~ 1

Author(s):

Tahar Bartil ◽

Mahmoud Bounekhel ◽

Cedric Calberg ◽

Robert Jerome

Keyword(s):

Ethylene Glycol ◽

Poly Ethylene Glycol ◽

Poly Ethylene

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Faculty Opinions recommendation of Impact of degradable macromer content in a poly(ethylene glycol) hydrogel on neural cell metabolic activity, redox state, proliferation, and differentiation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5382959.5337059 ◽

2010 ◽

Author(s):

Jennifer Elisseeff

Keyword(s):

Ethylene Glycol ◽

Metabolic Activity ◽

Redox State ◽

Neural Cell ◽

Poly Ethylene Glycol ◽

Cell Metabolic Activity ◽

Proliferation And Differentiation ◽

Poly Ethylene

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Investigation of Morphology and Structure of Poly(ethylene glycol)-Coated Silver Nanowires by Electron Microscopy

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION) ◽

10.3724/sp.j.1096.2010.00149 ◽

2010 ◽

Vol 38 (2) ◽

pp. 149-152

Author(s):

Li-Jian HUANG ◽

Er-Kang WANG

Keyword(s):

Electron Microscopy ◽

Ethylene Glycol ◽

Silver Nanowires ◽

Poly Ethylene Glycol ◽

Morphology And Structure ◽

Poly Ethylene

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