Atypical Effects of Salts on the Stability and Iron Release Kinetics of Human Transferrin

2009 ◽  
Vol 113 (36) ◽  
pp. 12400-12409 ◽  
Author(s):  
Rajesh Kumar ◽  
A. Grant Mauk
Keyword(s):  
Release Kinetics ◽  
Iron Release ◽  
Human Transferrin ◽  
The Stability ◽  
Kinetics Of

Electrostatic effects control the stability and iron release kinetics of ovotransferrin

2014 ◽  
Vol 19 (6) ◽  
pp. 1009-1024 ◽  
Author(s):  
Sandeep Kumar ◽  
Deepak Sharma ◽  
Rajesh Kumar ◽  
Rajesh Kumar
Keyword(s):  
Release Kinetics ◽  
Iron Release ◽  
Electrostatic Effects ◽  
The Stability ◽  
Kinetics Of

The role of microsphere fabrication methods on the stability and release kinetics of ovalbumin encapsulated in polyanhydride microspheres

2006 ◽  
Vol 23 (8) ◽  
pp. 832-843 ◽  
Author(s):  
Amy S. Determan ◽  
Jennifer R. Graham ◽  
Katherine A. Pfeiffer ◽  
Balaji Narasimhan
Keyword(s):  
Release Kinetics ◽  
The Stability ◽  
Kinetics Of

scholarly journals Antibacterial Activity and Iron Release of Organic-Inorganic Hybrid Biomaterials Synthesized via the Sol-Gel Route

2021 ◽  
Vol 11 (19) ◽  
pp. 9311
Author(s):  
Michelina Catauro ◽  
Ylenia D’Errico ◽  
Antonio D’Angelo ◽  
Ronald J. Clarke ◽  
Ignazio Blanco
Keyword(s):  
Hybrid Materials ◽  
Release Kinetics ◽  
Sol Gel ◽  
Antibacterial Properties ◽  
Iron Release ◽  
Biological Characterization ◽  
Visible Spectroscopy ◽  
E Coli ◽  
Hybrid Biomaterials ◽  
Kinetics Of

The aim of this work was the synthesis of hybrid materials of iron (II)-based therapeutic systems via the sol-gel method. Increasing amounts of polyethylene glycol (PEG 6, 12, 24, 50 wt%) were added to SiO2/Fe20 wt% to modulate the release kinetics of the drug from the systems. Fourier-transform infrared (FTIR) spectroscopy was used to study the interactions between different components in the hybrid materials. The release kinetics in a simulated body fluid (SBF) were investigated, and the amount of Fe2+ released was detected via ultraviolet-visible spectroscopy (UV-Vis) after reaction with ortho-phenanthroline. Furthermore, biological characterization was carried out. The bioactivity of the synthesized hybrid materials was evaluated via the formation of a layer of hydroxyapatite on the surface of samples soaked in SBF using spectroscopy. Finally, the potential antibacterial properties of seven different materials against two different bacteria—E. coli and S. aureus—were investigated.

The effect of pH on the kinetics of iron release from human transferrin

1982 ◽  
Vol 719 (1) ◽  
pp. 140-146 ◽  
Author(s):  
David A. Baldwin ◽  
Deolinda M.R. De Sousa ◽  
Rainer M.A. Von Wandruszka
Keyword(s):  
Iron Release ◽  
Effect Of Ph ◽  
Human Transferrin ◽  
Kinetics Of

scholarly journals Preparation, Characterization, and Release Kinetics of Chitosan-Coated Nanoliposomes Encapsulating Curcumin in Simulated Environments

Molecules ◽  
2019 ◽  
Vol 24 (10) ◽  
pp. 2023 ◽  
Author(s):  
Mahmoud Hasan ◽  
Kamil Elkhoury ◽  
Cyril J. F. Kahn ◽  
Elmira Arab-Tehrany ◽  
Michel Linder
Keyword(s):  
Release Kinetics ◽  
Physicochemical Characteristics ◽  
Biological Properties ◽  
Lipophilic Compounds ◽  
Simulated Environments ◽  
Natural Polyphenol ◽  
Poorly Soluble ◽  
The Stability ◽  
Kinetics Of ◽  
Low Solubility

Curcumin, a natural polyphenol, has many biological properties, such as anti-inflammatory, antioxidant, and anti-carcinogenic properties, yet, its sensitivity to light, oxygen, and heat, and its low solubility in water renders its preservation and bioavailability challenging. To increase its bioaccessibility, we fabricated nanoliposomes and chitosan-coated nanoliposomes encapsulating curcumin, and we evaluated the systems in terms of their physicochemical characteristics and release profiles in simulated gastrointestinal mediums. Chitosan-coating enhanced the stability of nanoliposomes and slowed the release of curcumin in the simulated gastrointestinal (GI) environment. This study demonstrates that nanoliposomes and chitosan-coated nanoliposomes are promising carriers for poorly soluble lipophilic compounds with low oral bioavailability, such as curcumin.

scholarly journals Pectin-Based Nanomaterials: Synthesis, Toxicity and Applications

2021 ◽  
Vol 33 (11) ◽  
pp. 2579-2588
Author(s):  
Mandeep Kaur ◽  
Aditya Wadhwa ◽  
Vineet Kumar
Keyword(s):  
Drug Delivery ◽  
Human Body ◽  
Release Kinetics ◽  
Drug Carrier ◽  
Biological Origin ◽  
Nanomaterials Synthesis ◽  
The Stability ◽  
Kinetics Of

Nanomaterials of biological origin are very useful for drug delivery applications. The stability, biodegradability and biocompatibility of pectin nanomaterials in the human body make them an effective drug carrier. This review focus on different aspect of synthesis, drug encapsulation, drug release and safety of pectin-based nanomaterials. The nanomaterials can be used for the delivery of different hydrophilic and hydrophobic drugs to various organs. The release kinetics of drug loaded pectin-based nanoparticles can be studied in vitro as well as in vivo. The pectin-based nanomaterials have good pharmaco-kinetics and can ensure controlled drug delivery. However, the toxicity of pectin-based nanomaterials to human body needs to be evaluated carefully before industrial scale application.

Sign in / Sign up

Export Citation Format

Share Document