scholarly journals Novel Methodology for Predicting the Critical Salt Concentration of Bubble Coalescence Inhibition

2014 ◽  
Vol 118 (2) ◽  
pp. 1021-1026 ◽  
Author(s):  
Mahshid Firouzi ◽  
Anh V. Nguyen
Keyword(s):  
Salt Concentration ◽  
Bubble Coalescence ◽  
Critical Salt Concentration

scholarly journals Multiphase Complex Coacervate Droplets

2020 ◽  
Author(s):  
Tie-Mei Lu ◽  
Evan Spruijt
Keyword(s):  
Liquid Phase ◽  
Salt Concentration ◽  
Condensed Phases ◽  
Cellular Organization ◽  
Guest Molecules ◽  
Interfacial Tensions ◽  
Hierarchical Arrangement ◽  
Self Organized ◽  
Critical Salt Concentration ◽  
Liquid Liquid Phase Separation

Liquid-liquid phase separation plays an important role in cellular organization. Many subcellular condensed bodies are hierarchically organized into multiple coexisting domains or layers. However, our molecular understanding of the assembly and internal organization of these multicomponent droplets is still incomplete, and rules for the coexistence of condensed phases are lacking. Here, we show that the formation of hierarchically organized multiphase droplets with up to three coexisting layers is a generic phenomenon in mixtures of complex coacervates, which serve as models of charge-driven liquid-liquid phase separated systems. We present simple theoretical guidelines to explain both the hierarchical arrangement and the demixing transition in multiphase droplets using the interfacial tensions and critical salt concentration as inputs. Multiple coacervates can coexist if they differ sufficiently in macromolecular density, and we show that the associated differences in critical salt concentration can be used to predict multiphase droplet formation. We also show that the coexisting coacervates present distinct chemical environments that can concentrate guest molecules to different extents. Our findings suggest that condensate immiscibility may be a very general feature in biological systems, which could be exploited to design self-organized synthetic compartments to control biomolecular processes.<br>

scholarly journals Multiphase Complex Coacervate Droplets

2020 ◽  
Author(s):  
Tie-Mei Lu ◽  
Evan Spruijt
Keyword(s):  
Liquid Phase ◽  
Salt Concentration ◽  
Condensed Phases ◽  
Cellular Organization ◽  
Guest Molecules ◽  
Interfacial Tensions ◽  
Hierarchical Arrangement ◽  
Self Organized ◽  
Critical Salt Concentration ◽  
Liquid Liquid Phase Separation

Liquid-liquid phase separation plays an important role in cellular organization. Many subcellular condensed bodies are hierarchically organized into multiple coexisting domains or layers. However, our molecular understanding of the assembly and internal organization of these multicomponent droplets is still incomplete, and rules for the coexistence of condensed phases are lacking. Here, we show that the formation of hierarchically organized multiphase droplets with up to three coexisting layers is a generic phenomenon in mixtures of complex coacervates, which serve as models of charge-driven liquid-liquid phase separated systems. We present simple theoretical guidelines to explain both the hierarchical arrangement and the demixing transition in multiphase droplets using the interfacial tensions and critical salt concentration as inputs. Multiple coacervates can coexist if they differ sufficiently in macromolecular density, and we show that the associated differences in critical salt concentration can be used to predict multiphase droplet formation. We also show that the coexisting coacervates present distinct chemical environments that can concentrate guest molecules to different extents. Our findings suggest that condensate immiscibility may be a very general feature in biological systems, which could be exploited to design self-organized synthetic compartments to control biomolecular processes.<br>

Proteins in Fish Muscle. IV. Denaturation by Salt

1952 ◽  
Vol 8c (5) ◽  
pp. 325-331 ◽  
Author(s):  
J. D. Duerr ◽  
W. J. Dyer
Keyword(s):  
Sodium Chloride ◽  
Salt Concentration ◽  
Fish Muscle ◽  
Moisture Loss ◽  
Sudden Increase ◽  
Muscle Proteins ◽  
Salt Uptake ◽  
Critical Salt Concentration

Study of the denaturation of cod muscle proteins by sodium chloride shows that the myosin fraction is denatured when a critical salt concentration, about 8 to 10 per cent in the muscle, is reached. Paralleling the rapid denaturation, a sudden increase of salt uptake and of moisture loss occurs.

Inhibition of bubble coalescence: Effects of salt concentration and speed of approach

2011 ◽  
Vol 356 (1) ◽  
pp. 316-324 ◽  
Author(s):  
Lorena A. Del Castillo ◽  
Satomi Ohnishi ◽  
Roger G. Horn
Keyword(s):  
Salt Concentration ◽  
Bubble Coalescence

Self-diffusion study of bile salt-monoolein micelles determination of the intermicellar bile salt concentration

1983 ◽  
Vol 80 ◽  
pp. 315-323 ◽  
Author(s):  
Marc Lindheimer ◽  
Jean-Claude Montet ◽  
Roselyne Bontemps ◽  
Jacques Rouviere ◽  
Bernard Brun
Keyword(s):  
Bile Salt ◽  
Salt Concentration ◽  
Diffusion Study ◽  
Bile Salt Concentration ◽  
Self Diffusion
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