Autoacetylation Induced Specific Structural Changes in Histone Acetyltransferase Domain of p300:  Probed by Surface Enhanced Raman Spectroscopy

2007 ◽  
Vol 111 (41) ◽  
pp. 11877-11879 ◽  
Author(s):  
Mohammed Arif ◽  
G. V. Pavan Kumar ◽  
Chandrabhas Narayana ◽  
Tapas K. Kundu
1992 ◽  
Vol 271 ◽  
Author(s):  
Beatrice A. Van Vlierberge-Torgerson ◽  
Dilum Dunuwila ◽  
Kris A. Berglund

ABSTRACTPorous stable metal-organic films can be processed under mild conditions by the hydrolysis of carboxylic acid and titanium isopropoxide mixtures. It is of importance to establish the structure of such materials. Raman spectroscopy is a useful technique in determining structural changes in titanium isopropoxide carboxylate solutions, but weak scattering does not allow for study of thin films unless surface enhancement is used. In an attempt to elucidate the relationship between coating solutions and the final structure of a cast film, we discuss Raman spectra of precursor solutions in a variety of conditions.


2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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