Development of a Fitting Model Suitable for the Isothermal Titration Calorimetric Curve of DNA with Cationic Ligands

2006 ◽  
Vol 110 (22) ◽  
pp. 10919-10925 ◽  
Author(s):  
Wankee Kim ◽  
Yuichi Yamasaki ◽  
Kazunori Kataoka
Keyword(s):  
Fitting Model ◽  
Calorimetric Curve

scholarly journals 1/f Noise Modelling and Characterization for CMOS Quanta Image Sensors

Sensors ◽  
2019 ◽  
Vol 19 (24) ◽  
pp. 5459
Author(s):  
Wei Deng ◽  
Eric R. Fossum
Keyword(s):  
Analog Circuits ◽  
Image Sensor ◽  
Image Sensors ◽  
Correlated Double Sampling ◽  
Cmos Image Sensors ◽  
Source Follower ◽  
Cmos Analog Circuits ◽  
Different Origins ◽  
Noise Models ◽  
Fitting Model

This work fits the measured in-pixel source-follower noise in a CMOS Quanta Image Sensor (QIS) prototype chip using physics-based 1/f noise models, rather than the widely-used fitting model for analog designers. This paper discusses the different origins of 1/f noise in QIS devices and includes correlated double sampling (CDS). The modelling results based on the Hooge mobility fluctuation, which uses one adjustable parameter, match the experimental measurements, including the variation in noise from room temperature to –70 °C. This work provides useful information for the implementation of QIS in scientific applications and suggests that even lower read noise is attainable by further cooling and may be applicable to other CMOS analog circuits and CMOS image sensors.

165 Effects of Digestible Lysine Level on Growth Performance and Economics of Grow-finish Pigs

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 58-59
Author(s):  
Larissa L Becker ◽  
Emily E Scholtz ◽  
Joel M DeRouchey ◽  
Mike D Tokach ◽  
Jason C Woodworth ◽  
...  
Keyword(s):  
Phase 1 ◽  
Information Criterion ◽  
Response Curves ◽  
Phase 3 ◽  
Ileal Digestibility ◽  
Distillers Dried Grains ◽  
Feed Cost ◽  
Best Fitting ◽  
Dietary Treatments ◽  
Fitting Model

Abstract A total of 2,124 barrows and gilts (PIC 1050′DNA 600, initially 48.9 kg) were used in a 32-d study to determine the optimal dietary standardized ileal digestibility (SID) Lys level in a commercial setting. Pigs were randomly allotted to 1 of 5 dietary treatments with 24 to 27 pigs/pen and 16 replications/treatment. Similar number of barrows and gilts were placed in each pen. Diets were fed over 3 phases (48.9 to 58.6, 58.6 to 70.9, and 70.9 to 80.8 kg respectively). Dietary treatments were corn-soybean meal-based and contained 10 (phase 1 and 2) or 5% (phase 3) distillers dried grains with solubles. Diets were formulated to 85, 95, 103, 110, or 120% of the current Pig Improvement Company (PIC, Hendersonville, TN) SID Lys gilt recommendations with phase 1 SID Lys levels of 0.90, 1.01, 1.09, 1.17 and 1.27%, phase 2 levels of 0.79, 0.87, 0.94, 1.03, and 1.10%, and phase 3 levels of 0.71, 0.78, 0.85, 0.92, and 0.99%, respectively. Dose response curves were evaluated using linear (LM), quadratic polynomial (QP), broken-line linear (BLL), and broken-line quadratic (BLQ) models. For each response variable, the best-fitting model was selected using the Bayesian information criterion. Overall (d 0 to 32), increasing SID Lys increased (linear, P< 0.001) BW, ADG, G:F, Lys intake/d, and Lys intake/kg of gain. Modeling margin over feed cost (MOFC), BLL and QP estimated the requirement at 105.8% and 113.7% respectively. In summary, while growth increased linearly up to 120% of the PIC current feeding level, the optimal MOFC was 106% to 114% depending on the model used.

Genetic and Environmental Influences of Dietary Indices in a UK Female Twin Cohort

2020 ◽  
Vol 23 (6) ◽  
pp. 330-337
Author(s):  
Olatz Mompeo ◽  
Rachel Gibson ◽  
Paraskevi Christofidou ◽  
Tim D. Spector ◽  
Cristina Menni ◽  
...  
Keyword(s):  
Healthy Eating ◽  
Menopausal Status ◽  
Healthy Eating Index ◽  
Healthy Diet ◽  
Nutritional Epidemiology ◽  
Best Fitting ◽  
Heritability Estimates ◽  
Fitting Model ◽  
Dietary Indices ◽  
Health Parameters

AbstractA healthy diet is associated with the improvement or maintenance of health parameters, and several indices have been proposed to assess diet quality comprehensively. Twin studies have found that some specific foods, nutrients and food patterns have a heritable component; however, the heritability of overall dietary intake has not yet been estimated. Here, we compute heritability estimates of the nine most common dietary indices utilized in nutritional epidemiology. We analyzed 2590 female twins from TwinsUK (653 monozygotic [MZ] and 642 dizygotic [DZ] pairs) who completed a 131-item food frequency questionnaire (FFQ). Heritability estimates were computed using structural equation models (SEM) adjusting for body mass index (BMI), smoking status, Index of Multiple Deprivation (IMD), physical activity, menopausal status, energy and alcohol intake. The AE model was the best-fitting model for most of the analyzed dietary scores (seven out of nine), with heritability estimates ranging from 10.1% (95% CI [.02, .18]) for the Dietary Reference Values (DRV) to 42.7% (95% CI [.36, .49]) for the Alternative Healthy Eating Index (A-HEI). The ACE model was the best-fitting model for the Healthy Diet Indicator (HDI) and Healthy Eating Index 2010 (HEI-2010) with heritability estimates of 5.4% (95% CI [−.17, .28]) and 25.4% (95% CI [.05, .46]), respectively. Here, we find that all analyzed dietary indices have a heritable component, suggesting that there is a genetic predisposition regulating what you eat. Future studies should explore genes underlying dietary indices to further understand the genetic disposition toward diet-related health parameters.

Comparing productive vocabulary measures from the CDI and a systematic diary study

1999 ◽  
Vol 26 (1) ◽  
pp. 177-185 ◽  
Author(s):  
BYRON F. ROBINSON ◽  
CAROLYN B. MERVIS
Keyword(s):  
Growth Curves ◽  
Diary Study ◽  
Expressive Vocabulary ◽  
Early Language ◽  
Vocabulary Size ◽  
Early Language Development ◽  
Closed Class ◽  
Communicative Development ◽  
Best Fitting ◽  
Fitting Model

Expressive vocabulary data gathered during a systematic diary study of one male child's early language development are compared to data that would have resulted from longitudinal administration of the MacArthur Communicative Development Inventories spoken vocabulary checklist (CDI). Comparisons are made for (1) the number of words at monthly intervals (9;10.15 to 2;0.15), (2) proportion of words by lexical class (i.e. noun, predicate, closed class, ‘other’), (3) growth curves. The CDI underestimates the number of words in the diary study, with the underestimation increasing as vocabulary size increases. The proportion of diary study words appearing on the CDI differed as a function of lexical class. Finally, despite the differences in vocabulary size, logistic curves proved to be the best fitting model to characterize vocabulary development as measured by both the diary study and the CDI. Implications for the longitudinal use of the CDI are discussed.

scholarly journals Developing Practical Models of Complex Salts for Molten Salt Reactors

Thermo ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 168-178
Author(s):  
Theodore M. Besmann ◽  
Juliano Schorne-Pinto
Keyword(s):  
Molten Salt ◽  
Nearest Neighbor ◽  
System Modeling ◽  
Model Parameters ◽  
Calphad Approach ◽  
Coordination Numbers ◽  
Regression Methods ◽  
Complex Salts ◽  
Salt Systems ◽  
Fitting Model

Molten salt reactors (MSRs) utilize salts as coolant or as the fuel and coolant together with fissile isotopes dissolved in the salt. It is necessary to therefore understand the behavior of the salts to effectively design, operate, and regulate such reactors, and thus there is a need for thermodynamic models for the salt systems. Molten salts, however, are difficult to represent as they exhibit short-range order that is dependent on both composition and temperature. A widely useful approach is the modified quasichemical model in the quadruplet approximation that provides for consideration of first- and second-nearest-neighbor coordination and interactions. Its use in the CALPHAD approach to system modeling requires fitting parameters using standard thermodynamic data such as phase equilibria, heat capacity, and others. A shortcoming of the model is its inability to directly vary coordination numbers with composition or temperature. Another issue is the difficulty in fitting model parameters using regression methods without already having very good initial values. The proposed paper will discuss these issues and note some practical methods for the effective generation of useful models.

Data Analysis and Forecast for Aircraft Structure Impact Damage Based on GP Symbolic Fitting Method

2011 ◽  
Vol 217-218 ◽  
pp. 701-705
Author(s):  
Man Yi Hou ◽  
Hui Lin Fan ◽  
Wu Lin Zhu
Keyword(s):  
Impact Damage ◽  
Aircraft Structure ◽  
Matlab Program ◽  
Fitting Method ◽  
Sample Data ◽  
Damage Data ◽  
Impact Parameters ◽  
The Times ◽  
The Impact ◽  
Fitting Model

In order to research the aircraft impact damage, one symbolic fitting method for analyzing and forecasting the damage data is proposed based on genetic programming (GP). The method can be used to forecast the impact damage by recognizing the rule in some groups of actual data including impact parameters and damage hole size. The principle of GP symbolic fitting method is briefly introduced. The fitting model is created with some sample data respectively for training and testing from Sorenson experiential equation. The computation with Matlab program indicates the model has a good performance to fit and forecast the damage data with avoiding the noise. The application of GP symbolic fitting method can help to decrease the times of fire experiments. Since the method can recognize the complicated nonlinear relationship between the impact parameters and damage data, it is more applicable than theoretical analysis and experiential equation to forecast the aircraft impact damage.

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